Department of Orthopaedic Surgery,
Department of Molecular & Integrative Physiology
Christopher L. Mendias has not added Biography.
If you are Christopher L. Mendias and would like to personalize this page please email our Author Liaison for assistance.
Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice.
Journal of applied physiology (Bethesda, Md. : 1985) Aug, 2014 | Pubmed ID: 24994884
Muscle fibers are injured at the time of acute and chronic rotator cuff repair.
Clinical orthopaedics and related research Jan, 2015 | Pubmed ID: 25113269
Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion.
Muscle & nerve Oct, 2004 | Pubmed ID: 15372441
Contractile properties of EDL and soleus muscles of myostatin-deficient mice.
Journal of applied physiology (Bethesda, Md. : 1985) Sep, 2006 | Pubmed ID: 16709649
Tendons of myostatin-deficient mice are small, brittle, and hypocellular.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2008 | Pubmed ID: 18162552
The aging of elite male athletes: age-related changes in performance and skeletal muscle structure and function.
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine Nov, 2008 | Pubmed ID: 19001883
Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation.
Journal of applied physiology (Bethesda, Md. : 1985) Jul, 2011 | Pubmed ID: 21565991
Physiological loading of tendons induces scleraxis expression in epitenon fibroblasts.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Apr, 2012 | Pubmed ID: 21913219
Transforming growth factor-beta induces skeletal muscle atrophy and fibrosis through the induction of atrogin-1 and scleraxis.
Muscle & nerve Jan, 2012 | Pubmed ID: 22190307
TGF-β1 enhances contractility in engineered skeletal muscle.
Journal of tissue engineering and regenerative medicine Jul, 2013 | Pubmed ID: 22371337
Mechanical loading and TGF-β change the expression of multiple miRNAs in tendon fibroblasts.
Journal of applied physiology (Bethesda, Md. : 1985) Jul, 2012 | Pubmed ID: 22539168
Rotator cuff tear reduces muscle fiber specific force production and induces macrophage accumulation and autophagy.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Dec, 2012 | Pubmed ID: 22696414
Hyaluronic acid, HAS1, and HAS2 are significantly upregulated during muscle hypertrophy.
American journal of physiology. Cell physiology Sep, 2012 | Pubmed ID: 22785117
Atrogin-1, MuRF-1, and sarcopenia.
Endocrine Feb, 2013 | Pubmed ID: 22815045
MMP inhibition as a potential method to augment the healing of skeletal muscle and tendon extracellular matrix.
Journal of applied physiology (Bethesda, Md. : 1985) Sep, 2013 | Pubmed ID: 23640595
Changes in circulating biomarkers of muscle atrophy, inflammation, and cartilage turnover in patients undergoing anterior cruciate ligament reconstruction and rehabilitation.
The American journal of sports medicine Aug, 2013 | Pubmed ID: 23739685
Targeted inhibition of TGF-β results in an initial improvement but long term deficit in force production after contraction-induced skeletal muscle injury.
Journal of applied physiology (Bethesda, Md. : 1985) Jun, 2013 | Pubmed ID: 23766498
Aging-associated exacerbation in fatty degeneration and infiltration after rotator cuff tear.
Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.] Jun, 2013 | Pubmed ID: 23790676
Elevation in circulating biomarkers of cartilage damage and inflammation in athletes with femoroacetabular impingement.
The American journal of sports medicine Nov, 2013 | Pubmed ID: 23959964
Changes in macrophage phenotype and induction of epithelial-to-mesenchymal transition genes following acute Achilles tenotomy and repair.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Jul, 2014 | Pubmed ID: 24700411
Reduced muscle fiber force production and disrupted myofibril architecture in patients with chronic rotator cuff tears.
Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.] Jan, 2015 | Pubmed ID: 25193488
Simvastatin reduces fibrosis and protects against muscle weakness after massive rotator cuff tear.
Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.] Feb, 2015 | Pubmed ID: 25213828
Inhibition of 5-LOX, COX-1, and COX-2 increases tendon healing and reduces muscle fibrosis and lipid accumulation after rotator cuff repair.
The American journal of sports medicine Dec, 2014 | Pubmed ID: 25245131
Synergist ablation induces rapid tendon growth through the synthesis of a neotendon matrix.
Journal of applied physiology (Bethesda, Md. : 1985) Dec, 2014 | Pubmed ID: 25277742
Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia.
Nature medicine Jan, 2015 | Pubmed ID: 25501907
TGF-β superfamily signaling in muscle and tendon adaptation to resistance exercise.
Exercise and sport sciences reviews Apr, 2015 | Pubmed ID: 25607281
Changes in skeletal muscle and tendon structure and function following genetic inactivation of myostatin in rats.
The Journal of physiology Apr, 2015 | Pubmed ID: 25640143
Mouse forepaw lumbrical muscles are resistant to age-related declines in force production.
Experimental gerontology May, 2015 | Pubmed ID: 25762422
p38 MAPK signaling in postnatal tendon growth and remodeling.
PloS one , 2015 | Pubmed ID: 25768932
Haploinsufficiency of myostatin protects against aging-related declines in muscle function and enhances the longevity of mice.
Aging cell Mar, 2015 | Pubmed ID: 25808276
Ex Situ Limb Perfusion System to Extend Vascularized Composite Tissue Allograft Survival in Swine.
Transplantation Apr, 2015 | Pubmed ID: 25929606
Stuart M. Roche1,
Jonathan P. Gumucio1,2,
Susan V. Brooks2,3,
Christopher L. Mendias1,2,
Dennis R. Claflin3,4
1Department of Orthopaedic Surgery, University of Michigan Medical School,
2Department of Molecular & Integrative Physiology, University of Michigan Medical School,
3Department of Biomedical Engineering, University of Michigan Medical School,
4Department of Surgery, Section of Plastic Surgery, University of Michigan Medical School
ACERCA DE JoVE
Copyright © 2024 MyJoVE Corporation. Todos los derechos reservados