Christopher L. Mendias

Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice.

Muscle fibers are injured at the time of acute and chronic rotator cuff repair.

Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion.

Contractile properties of EDL and soleus muscles of myostatin-deficient mice.

Tendons of myostatin-deficient mice are small, brittle, and hypocellular.

The aging of elite male athletes: age-related changes in performance and skeletal muscle structure and function.

Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation.

Physiological loading of tendons induces scleraxis expression in epitenon fibroblasts.

Transforming growth factor-beta induces skeletal muscle atrophy and fibrosis through the induction of atrogin-1 and scleraxis.

TGF-β1 enhances contractility in engineered skeletal muscle.

Mechanical loading and TGF-β change the expression of multiple miRNAs in tendon fibroblasts.

Rotator cuff tear reduces muscle fiber specific force production and induces macrophage accumulation and autophagy.

Hyaluronic acid, HAS1, and HAS2 are significantly upregulated during muscle hypertrophy.

Atrogin-1, MuRF-1, and sarcopenia.

MMP inhibition as a potential method to augment the healing of skeletal muscle and tendon extracellular matrix.

Changes in circulating biomarkers of muscle atrophy, inflammation, and cartilage turnover in patients undergoing anterior cruciate ligament reconstruction and rehabilitation.

Targeted inhibition of TGF-β results in an initial improvement but long term deficit in force production after contraction-induced skeletal muscle injury.

Aging-associated exacerbation in fatty degeneration and infiltration after rotator cuff tear.

Elevation in circulating biomarkers of cartilage damage and inflammation in athletes with femoroacetabular impingement.

Changes in macrophage phenotype and induction of epithelial-to-mesenchymal transition genes following acute Achilles tenotomy and repair.

Reduced muscle fiber force production and disrupted myofibril architecture in patients with chronic rotator cuff tears.

Simvastatin reduces fibrosis and protects against muscle weakness after massive rotator cuff tear.

Inhibition of 5-LOX, COX-1, and COX-2 increases tendon healing and reduces muscle fibrosis and lipid accumulation after rotator cuff repair.

Synergist ablation induces rapid tendon growth through the synthesis of a neotendon matrix.

Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia.

TGF-β superfamily signaling in muscle and tendon adaptation to resistance exercise.

Changes in skeletal muscle and tendon structure and function following genetic inactivation of myostatin in rats.

Mouse forepaw lumbrical muscles are resistant to age-related declines in force production.

p38 MAPK signaling in postnatal tendon growth and remodeling.

Haploinsufficiency of myostatin protects against aging-related declines in muscle function and enhances the longevity of mice.

Ex Situ Limb Perfusion System to Extend Vascularized Composite Tissue Allograft Survival in Swine.