Team "Signal Division Regulation"
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The Yersinia pseudotuberculosis Yut protein, a new type of urea transporter homologous to eukaryotic channels and functionally interchangeable in vitro with the Helicobacter pylori UreI protein.
Molecular microbiology Aug, 2002 | Pubmed ID: 12180933
The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta.
Molecular and cellular biology Oct, 2002 | Pubmed ID: 12242277
Inhibition of FGF receptor signalling in Xenopus oocytes: differential effect of Grb7, Grb10 and Grb14.
FEBS letters Jul, 2003 | Pubmed ID: 12885405
The PIR domain of Grb14 is an intrinsically unstructured protein: implication in insulin signaling.
FEBS letters Nov, 2003 | Pubmed ID: 14623073
Conservation of epidermal growth factor receptor function in the human parasitic helminth Schistosoma mansoni.
The Journal of biological chemistry Sep, 2004 | Pubmed ID: 15231836
ERK2 is required for FGF1-induced JNK1 phosphorylation in Xenopus oocyte expressing FGF receptor 1.
Biochimica et biophysica acta Mar, 2005 | Pubmed ID: 15777834
The Ste20-like kinase SLK is required for cell cycle progression through G2.
The Journal of biological chemistry Dec, 2005 | Pubmed ID: 16236704
FGF receptor phosphotyrosine 766 is a target for Grb14 to inhibit MDA-MB-231 human breast cancer cell signaling.
Anticancer research Nov-Dec, 2005 | Pubmed ID: 16309174
Characterization of Schistosoma mansoni Sds homologue, a leucine-rich repeat protein that interacts with protein phosphatase type 1 and interrupts a G2/M cell-cycle checkpoint.
The Biochemical journal Apr, 2006 | Pubmed ID: 16411888
Regulation of protein phosphatase type 1 and cell cycle progression by PfLRR1, a novel leucine-rich repeat protein of the human malaria parasite Plasmodium falciparum.
Molecular microbiology May, 2006 | Pubmed ID: 16629662
The alphavirus 6K protein activates endogenous ionic conductances when expressed in Xenopus oocytes.
The Journal of membrane biology Jan, 2007 | Pubmed ID: 17483865
Molecular cloning and characterisation of SmSLK, a novel Ste20-like kinase in Schistosoma mansoni.
International journal for parasitology Dec, 2007 | Pubmed ID: 17651740
A Toxoplasma gondii leucine-rich repeat protein binds phosphatase type 1 protein and negatively regulates its activity.
Eukaryotic cell Sep, 2007 | Pubmed ID: 17660360
A non-canonical Grb2-PLC-gamma1-Sos cascade triggered by lipovitellin 1, an apolipoprotein B homologue.
Cellular signalling Dec, 2007 | Pubmed ID: 17869481
A microinjectable biological system, the Xenopus oocyte, as an approach to understanding signal transduction protein function.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19085133
Molecular determinants of Grb14-mediated inhibition of insulin signaling.
Molecular endocrinology (Baltimore, Md.) Jul, 2009 | Pubmed ID: 19359342
Akt interaction with PLC(gamma) regulates the G(2)/M transition triggered by FGF receptors from MDA-MB-231 breast cancer cells.
Anticancer research Dec, 2009 | Pubmed ID: 20044603
Schistosoma mansoni Polo-like kinase 1: A mitotic kinase with key functions in parasite reproduction.
International journal for parasitology Aug, 2010 | Pubmed ID: 20350550
Calcium dynamics during physiological acidification in Xenopus oocyte.
The Journal of membrane biology Aug, 2010 | Pubmed ID: 20717657
Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation.
FEBS letters Nov, 2010 | Pubmed ID: 20932831
Schistosoma mansoni: structural and biochemical characterization of two distinct Venus Kinase Receptors.
Experimental parasitology Sep, 2012 | Pubmed ID: 21616067
Characterization of the Src/Abl hybrid kinase SmTK6 of Schistosoma mansoni.
The Journal of biological chemistry Dec, 2011 | Pubmed ID: 22013071
SmSak, the second Polo-like kinase of the helminth parasite Schistosoma mansoni: conserved and unexpected roles in meiosis.
PloS one , 2012 | Pubmed ID: 22768216
Discovery of platyhelminth-specific α/β-integrin families and evidence for their role in reproduction in Schistosoma mansoni.
PloS one , 2012 | Pubmed ID: 23300694
Dual targeting of insulin and venus kinase Receptors of Schistosoma mansoni for novel anti-schistosome therapy.
PLoS neglected tropical diseases , 2013 | Pubmed ID: 23696913
Transcriptome Analyses of Inhibitor-treated Schistosome Females Provide Evidence for Cooperating Src-kinase and TGFβ Receptor Pathways Controlling Mitosis and Eggshell Formation.
PLoS pathogens Jun, 2013 | Pubmed ID: 23785292
PhosphoTyrosyl phosphatase activator of Plasmodium falciparum: identification of its residues involved in binding to and activation of PP2A.
International journal of molecular sciences , 2014 | Pubmed ID: 24521882
Venus kinase receptors control reproduction in the platyhelminth parasite Schistosoma mansoni.
PLoS pathogens May, 2014 | Pubmed ID: 24875530
Targeting Echinococcus multilocularis stem cells by inhibition of the Polo-like kinase EmPlk1.
PLoS neglected tropical diseases Jun, 2014 | Pubmed ID: 24901228
Imatinib treatment causes substantial transcriptional changes in adult Schistosoma mansoni in vitro exhibiting pleiotropic effects.
PLoS neglected tropical diseases Jun, 2014 | Pubmed ID: 24921634
Gonad RNA-specific qRT-PCR analyses identify genes with potential functions in schistosome reproduction such as SmFz1 and SmFGFRs.
Frontiers in genetics , 2014 | Pubmed ID: 24959172
Compound library screening identified Akt/PKB kinase pathway inhibitors as potential key molecules for the development of new chemotherapeutics against schistosomiasis.
International journal for parasitology. Drugs and drug resistance Dec, 2014 | Pubmed ID: 25516836
Insulin-induced cell division is controlled by the adaptor Grb14 in a Chfr-dependent manner.
Cellular signalling Apr, 2015 | Pubmed ID: 25578860
Nitric Oxide Donor s-Nitroso-n-Acetyl Penicillamine (SNAP) Alters Meiotic Spindle Morphogenesis in Xenopus Oocytes.
Journal of cellular biochemistry Nov, 2015 | Pubmed ID: 25923058
RasGAP Shields Akt from Deactivating Phosphatases in Fibroblast Growth Factor Signaling but Loses This Ability Once Cleaved by Caspase-3.
The Journal of biological chemistry Aug, 2015 | Pubmed ID: 26109071
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