Charles D. Stiles

Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.

Molecular mechanisms controlling cortical gliogenesis.

High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors.

Basic helix-loop-helix factors in cortical development.

Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.

Lost in space: misregulated positional cues create tripotent neural progenitors in cell culture.

Expression of the guanine nucleotide exchange factor, mr-gef, is regulated during the differentiation of specific subsets of telencephalic neurons.

The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas.

Distinct temporal genetic signatures of neurogenic and gliogenic cues in cortical stem cell cultures.

bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.

Mouse brain organization revealed through direct genome-scale TF expression analysis.

Targeted molecular therapy of malignant gliomas.

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas.

Novel pheochromocytoma susceptibility loci identified by integrative genomics.

Targeted molecular therapy of malignant gliomas.

Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube.

Development of NG2 neural progenitor cells requires Olig gene function.

The bad seed: PDGF receptors link adult neural progenitors to glioma stem cells.

Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.

"Smad"eningly erratic: target gene methylation determines whether TGFbeta promotes or suppresses malignant glioma.

Molecular pathogenesis of adult brain tumors and the role of stem cells.

Glioma stem cells: a midterm exam.

Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08).

A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.

Profiling critical cancer gene mutations in clinical tumor samples.

Phosphorylation state of Olig2 regulates proliferation of neural progenitors.

The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma.

Report from the fifth National Cancer Institute Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop.

Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.

Identification of molecular compartments and genetic circuitry in the developing mammalian kidney.

Prospective, high-throughput molecular profiling of human gliomas.

Asleep at the switch: MEK kinases control transit to gliogenesis in developing cortex.

Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2.

Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.

Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging.

New progenitors NESTIN(g) in the EGL.

Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain.

An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells.

Of Brains and Blood: Developmental Origins of Glioma Diversity?