Centre for Biological Signalling Studies (bioss) and Biology III,
Faculty of Biology,
Centre for Biological Signalling Studies (bioss) and Biology III, Faculty of Biology
Wolfgang W. A. Schamel has not added Biography.
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Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation.
Cell Jun, 2002 | Pubmed ID: 12110186
Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop.
Molecular cell Nov, 2002 | Pubmed ID: 12453414
Initiation of TCR signaling: regulation within CD3 dimers.
Immunological reviews Feb, 2003 | Pubmed ID: 12614350
A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2003 | Pubmed ID: 12886015
Two-dimensional Blue native/SDS gel electrophoresis of multi-protein complexes from whole cellular lysates: a proteomics approach.
Molecular & cellular proteomics : MCP Feb, 2004 | Pubmed ID: 14665681
Biochemical differences in the alphabeta T cell receptor.CD3 surface complex between CD8+ and CD4+ human mature T lymphocytes.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15060077
Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors.
European journal of immunology Jan, 2005 | Pubmed ID: 15580656
Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response.
The Journal of experimental medicine Aug, 2005 | Pubmed ID: 16087711
Subproteomic analysis of metal-interacting proteins in human B cells.
Proteomics Sep, 2005 | Pubmed ID: 16097032
Differences in pairing and cluster formation of T cell receptor alpha- and beta-chains in T cell clones and fusion hybridomas.
Immunobiology , 2005 | Pubmed ID: 16323705
Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes.
Immunology letters Apr, 2006 | Pubmed ID: 16356554
A conformation- and avidity-based proofreading mechanism for the TCR-CD3 complex.
Trends in immunology Apr, 2006 | Pubmed ID: 16527543
T-cell antigen-receptor stoichiometry: pre-clustering for sensitivity.
EMBO reports May, 2006 | Pubmed ID: 16670682
Blue native polyacrylamide gel electrophoresis (BN-PAGE) for the identification and analysis of multiprotein complexes.
Science's STKE : signal transduction knowledge environment Jul, 2006 | Pubmed ID: 16868305
Identification of disulfide bonds in the Ig-alpha/Ig-beta component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system.
International immunology Sep, 2006 | Pubmed ID: 16877534
Overlapping functions of human CD3delta and mouse CD3gamma in alphabeta T-cell development revealed in a humanized CD3gamma-mouse.
Blood Nov, 2006 | Pubmed ID: 16888097
Full activation of the T cell receptor requires both clustering and conformational changes at CD3.
Immunity Jan, 2007 | Pubmed ID: 17188005
High-sensitivity detection and quantitative analysis of native protein-protein interactions and multiprotein complexes by flow cytometry.
Science's STKE : signal transduction knowledge environment Jun, 2007 | Pubmed ID: 17551170
A native antibody-based mobility-shift technique (NAMOS-assay) to determine the stoichiometry of multiprotein complexes.
Journal of immunological methods Jul, 2007 | Pubmed ID: 17568608
Different composition of the human and the mouse gammadelta T cell receptor explains different phenotypes of CD3gamma and CD3delta immunodeficiencies.
The Journal of experimental medicine Oct, 2007 | Pubmed ID: 17923503
The TCR binding site does move.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2007 | Pubmed ID: 17925433
A permissive geometry model for TCR-CD3 activation.
Trends in biochemical sciences Feb, 2008 | Pubmed ID: 18201888
The short length of the extracellular domain of zeta is crucial for T cell antigen receptor function.
Immunology letters Mar, 2008 | Pubmed ID: 18207249
The extracellular part of zeta is buried in the T cell antigen receptor complex.
Immunology letters Mar, 2008 | Pubmed ID: 18215426
T cell receptor engagement triggers its CD3epsilon and CD3zeta subunits to adopt a compact, locked conformation.
PloS one , 2008 | Pubmed ID: 18320063
Two-dimensional blue native polyacrylamide gel electrophoresis.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] Mar, 2008 | Pubmed ID: 18360818
Differential antibody binding to the surface alphabetaTCR.CD3 complex of CD4+ and CD8+ T lymphocytes is conserved in mammals and associated with differential glycosylation.
International immunology Oct, 2008 | Pubmed ID: 18653700
Purification of the T cell antigen receptor and analysis by blue-native PAGE.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19048218
Clustering models.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 19065784
Segregation models.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 19065785
Permissive geometry model.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 19065789
Detection of protein complex interactions via a Blue Native-PAGE retardation assay.
Analytical biochemistry Sep, 2009 | Pubmed ID: 19482002
Target-dependent T-cell activation by coligation with a PSMA x CD3 diabody induces lysis of prostate cancer cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) Jul-Aug, 2009 | Pubmed ID: 19483653
Models of antigen receptor activation in the design of vaccines.
Current pharmaceutical design , 2009 | Pubmed ID: 19860673
Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling.
Immunology letters May, 2010 | Pubmed ID: 20005895
Detection of phosphorylated T and B cell antigen receptor species by Phos-tag SDS- and Blue Native-PAGE.
Immunology letters May, 2010 | Pubmed ID: 20005898
Low-valency, but not monovalent, antigens trigger the B-cell antigen receptor (BCR).
International immunology Mar, 2010 | Pubmed ID: 20145007
Innate, antigen-independent role for T cells in the activation of the immune system by Propionibacterium acnes.
European journal of immunology Sep, 2010 | Pubmed ID: 20690177
Pre-clustered TCR complexes.
FEBS letters Dec, 2010 | Pubmed ID: 20828560
Quantitative analysis of protein phosphorylations and interactions by multi-colour IP-FCM as an input for kinetic modelling of signalling networks.
PloS one , 2011 | Pubmed ID: 21829558
A new vampire saga: the molecular mechanism of T cell trogocytosis.
Immunity Aug, 2011 | Pubmed ID: 21867922
Increased sensitivity of antigen-experienced T cells through the enrichment of oligomeric T cell receptor complexes.
Immunity Sep, 2011 | Pubmed ID: 21903423
A leaky mutation in CD3D differentially affects αβ and γδ T cells and leads to a Tαβ-Tγδ+B+NK+ human SCID.
The Journal of clinical investigation Oct, 2011 | Pubmed ID: 21926461
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