Stephane Gobeil

Intracellular sequestration of hetero-oligomers formed by wild-type and glaucoma-causing myocilin mutants.

Novel myocilin mutation in a Chinese family with juvenile-onset open-angle glaucoma.

Functional analysis of the glaucoma-causing TIGR/myocilin protein: integrity of amino-terminal coiled-coil regions and olfactomedin homology domain is essential for extracellular adhesion and secretion.

An elaborate pathway required for Ras-mediated epigenetic silencing.

A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene.

Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression.

RNA interference in mammals: behind the screen.

The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy.

A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.

Inhibition of RUNX2 transcriptional activity blocks the proliferation, migration and invasion of epithelial ovarian carcinoma cells.

MicroRNA-196a promotes an oncogenic effect in head and neck cancer cells by suppressing annexin A1 and enhancing radioresistance.

Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages.

BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism.

The mannose receptor LY75 (DEC205/CD205) modulates cellular phenotype and metastatic potential of ovarian cancer cells.

ABRAXAS (FAM175A) and Breast Cancer Susceptibility: No Evidence of Association in the Breast Cancer Family Registry.

Hypoxia-inducible factor-1 plays a role in phosphate-induced vascular smooth muscle cell calcification.

The histone H3K9 demethylase KDM3A promotes anoikis by transcriptionally activating pro-apoptotic genes BNIP3 and BNIP3L.