Three-Dimensional Culture Assay to Explore Cancer Cell Invasiveness and Satellite Tumor FormationMarie-France Côté 1, Audrey Turcotte 1,2, Charles Doillon 1,3, Stephane Gobeil 1,2
1CHU de Québec Research Centre, 2Department of Molecular Medicine, Laval University, 3Department of Surgery, Laval University
Cancer cells are embedded in a collagen gel and then sandwiched in an acellular fibrin gel to generate a 3D culture system in which the invasiveness and formation of satellite tumors may be monitored.