Ihor R. Lemischka

Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells.

Cells for repair: breakout session summary.

A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover.

A molecular profile of a hematopoietic stem cell niche.

A stem cell molecular signature.

Stem cells: interactive niches.

"Tie-ing" down the hematopoietic niche.

Stem cell biology: a view toward the future.

Diversification of stem cell molecular repertoire by alternative splicing.

Alternative splicing increases complexity of stem cell transcriptome.

Stem cells and their niches.

Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells.

Delivery of short hairpin RNAs--triggers of gene silencing--into mouse embryonic stem cells.

The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells.

Dissecting self-renewal in stem cells with RNA interference.

shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development.

A genomewide functional network for the laboratory mouse.

Alternative induced pluripotent stem cell characterization criteria for in vitro applications.

Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain.

Systems biology of stem cell fate and cellular reprogramming.

Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells.

Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2.

GATE: software for the analysis and visualization of high-dimensional time series expression data.

Systems-level dynamic analyses of fate change in murine embryonic stem cells.

Hooking up with Oct4.

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome.

Exploration of self-renewal and pluripotency in ES cells using RNAi.

Toward a complete in silico, multi-layered embryonic stem cell regulatory network.

SVM classifier to predict genes important for self-renewal and pluripotency of mouse embryonic stem cells.

Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells.

Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation.

Prdm16 is a physiologic regulator of hematopoietic stem cells.

Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells.

Induced pluripotent stem cell-derived cardiomyocytes as models for genetic cardiovascular disorders.

Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network.

Stem cells and reprogramming: breaking the epigenetic barrier?

Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells.

KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.

Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency.

Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling.

Reprogramming cell fates: insights from combinatorial approaches.

Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming.

Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity.

SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal.

Induction of a hemogenic program in mouse fibroblasts.

ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells.

Patterning pluripotency in embryonic stem cells.

Statistical mechanics of pluripotency.

Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm.

Epigenetic roles of MLL oncoproteins are dependent on NF-κB.

"There will be blood" from fibroblasts.

'From blood to blood': de-differentiation of hematopoietic progenitors to stem cells.

Genomic editing tools to model human diseases with isogenic pluripotent stem cells.

Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells.

A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming.

NetExplore: a web server for modeling small network motifs.

Modeling familial cancer with induced pluripotent stem cells.

Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming.

Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm.

Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen.

Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal.

Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia.

Making a Hematopoietic Stem Cell.

Converting cell fates: generating hematopoietic stem cells de novo via transcription factor reprogramming.

Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells.

Emerging Modeling Concepts and Solutions in Stem Cell Research.

A dual molecular analogue tuner for dissecting protein function in mammalian cells.

Modeling Cancer with Pluripotent Stem Cells.