Scott K. Durum

IL-7 withdrawal induces a stress pathway activating p38 and Jun N-terminal kinases.

Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax.

The role of cytokines in lymphocyte homeostasis.

Lymphocide: cytokines and the control of lymphoid homeostasis.

Bax deficiency partially corrects interleukin-7 receptor alpha deficiency.

Characterization of an interleukin-7-dependent thymic cell line derived from a p53(-/-) mouse.

Interleukin-7 induces MUC1.

Death and Baxes: mechanisms of lymphotrophic cytokines.

Bcl11: sibling rivalry in lymphoid development.

IL-7 induces tyrosine phosphorylation of clathrin heavy chain.

Interleukin-7 inactivates the pro-apoptotic protein Bad promoting T cell survival.

Distinct regions of the interleukin-7 receptor regulate different Bcl2 family members.

Cytokine-driven cell cycling is mediated through Cdc25A.

Cell biology of IL-7, a key lymphotrophin.

The adaptive immune response in neonatal cerebral white matter damage.

Stat5a/b are essential for normal lymphoid development and differentiation.

IL-7 promotes T cell proliferation through destabilization of p27Kip1.

Inflammatory processes triggered by TCR engagement or by local cytokine expression: differences in profiles of gene expression and infiltrating cell populations.

Role of the intracellular domain of IL-7 receptor in T cell development.

IL-7 induces myelopoiesis and erythropoiesis.

Interleukin-7 receptor expression: intelligent design.

The influence of IL-2 family cytokines on activation and function of naturally occurring regulatory T cells.

Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.

Live from the liver: hepatocyte IL-7.

Visualization and identification of IL-7 producing cells in reporter mice.

Synergy of IL-23 and Th17 cytokines: new light on inflammatory bowel disease.

Interleukin-7 regulates Bim proapoptotic activity in peripheral T-cell survival.

Cdc25A-driven proliferation regulates CD62L levels and lymphocyte movement in response to interleukin-7.

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.

Detection of nuclear and membrane antigens by liquid-based cytology following long-term storage of d1 cells, karpas cells, and peripheral blood mononuclear cells.

Th17 cells are long lived and retain a stem cell-like molecular signature.

The human IL-7 receptor gene: deletions, polymorphisms and mutations.

The major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes.

Regulation of in vitro human T cell development through interleukin-7 deprivation and anti-CD3 stimulation.

Oral Delivery of IL27 Recombinant Bacteria Attenuates Immune Colitis in Mice.

Stemness of T cells and the hematopoietic stem cells: fate, memory, niche, cytokines.

Targeting interleukins for the treatment of inflammatory bowel disease-what lies beyond anti-TNF therapy?

Chronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis.

IL-7 and TSLP receptors: twisted sisters.

Adaptive immunity to murine skin commensals.

Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets.

IL-22-Expressing Murine Lymphocytes Display Plasticity and Pathogenicity in Reporter Mice.

Development and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases.

Interleukin-27 as a Novel Therapy for Inflammatory Bowel Disease: A Critical Review of the Literature.

Therapeutic targeting of IL-7Rα signaling pathways in ALL treatment.

Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity.

The promise of Janus kinase inhibitors in the treatment of hematological malignancies.

Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia.

The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn's Disease-Like Ileitis.

Inhibiting Janus Kinase 1 and BCL-2 to treat T cell acute lymphoblastic leukemia with IL7-Rα mutations.

Cytokine Tuning of Intestinal Epithelial Function.

Can We Target Endogenous Anti-inflammatory Responses as a Therapeutic Strategy for Inflammatory Bowel Disease?

Clonal Vγ6Vδ4 T cells promote IL-17-mediated immunity against skin infection.

IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis.

New anti-IL-7Rα monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.

NRARP displays either pro- or anti-tumoral roles in T-cell acute lymphoblastic leukemia depending on Notch and Wnt signaling.

Mutations that collaborate with IL-7Ra signaling pathways to drive ALL.

Trained ILC3 responses promote intestinal defense.

Joost J. Oppenheim (1934-2022).

IL-7: Comprehensive review.

A Focused Review of Ras Guanine Nucleotide-Releasing Protein 1 in Immune Cells and Cancer.

IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium.