Paul S. Pagel

Isoflurane protects against myocardial infarction during early reperfusion by activation of phosphatidylinositol-3-kinase signal transduction: evidence for anesthetic-induced postconditioning in rabbits.

Role of endothelial nitric oxide synthase as a trigger and mediator of isoflurane-induced delayed preconditioning in rabbit myocardium.

Intraoperative iatrogenic acute pericardial tamponade: use of rescue transesophageal echocardiography in a patient undergoing orthotopic liver transplantation.

Morphine enhances isoflurane-induced postconditioning against myocardial infarction: the role of phosphatidylinositol-3-kinase and opioid receptors in rabbits.

Aggressive control of intraoperative blood glucose concentration: a shifting paradigm?

Isoflurane inhibits cardiac myocyte apoptosis during oxidative and inflammatory stress by activating Akt and enhancing Bcl-2 expression.

Axial stent strut angle influences wall shear stress after stent implantation: analysis using 3D computational fluid dynamics models of stent foreshortening.

Ischemia-reperfusion injury changes the dynamics of Ca2+-contraction coupling due to inotropic drugs in isolated hearts.

Inhibition of mitochondrial permeability transition enhances isoflurane-induced cardioprotection during early reperfusion: the role of mitochondrial KATP channels.

Role of Erk1/2, p70s6K, and eNOS in isoflurane-induced cardioprotection during early reperfusion in vivo.

Ischemia reperfusion dysfunction changes model-estimated kinetics of myofilament interaction due to inotropic drugs in isolated hearts.

Inhibition of glycogen synthase kinase enhances isoflurane-induced protection against myocardial infarction during early reperfusion in vivo.

The influence of B-cell lymphoma 2 protein, an antiapoptotic regulator of mitochondrial permeability transition, on isoflurane-induced and ischemic postconditioning in rabbits.

A circular structure in the aortic outflow tract during diastole: an unusual complication of cocaine abuse.

Alterations in regional vascular geometry produced by theoretical stent implantation influence distributions of wall shear stress: analysis of a curved coronary artery using 3D computational fluid dynamics modeling.

Cardioprotection by volatile anesthetics: new applications for old drugs?

Gender-specificity of delayed preconditioning by isoflurane in rabbits: potential role of endothelial nitric oxide synthase.

Extracellular signal-regulated kinases trigger isoflurane preconditioning concomitant with upregulation of hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in rats.

Nitrous oxide and preconditioning.

Inhibition of apoptotic protein p53 lowers the threshold of isoflurane-induced cardioprotection during early reperfusion in rabbits.

An unusual right atrial structure in a patient with a new diastolic murmur.

Levosimendan in cardiac surgery: a unique drug for the treatment of perioperative left ventricular dysfunction or just another inodilator searching for a clinical application?

Anesthetics and echocardiographic assessment of left ventricular function: lessons learned from invasive analysis of cardiovascular mechanics.

A widened mediastinum in a patient with a left parasternal stab wound.

A triple-lumen aorta: an unusual manifestation of complex aortic pathology associated with crack cocaine abuse.

Repetitive generalized seizure-like activity during emergence from sevoflurane anesthesia.

Perioperative implications of charcot-marie-tooth disease during coronary artery bypass graft surgery.

Case 4-2007. Aprotinin-induced cardiovascular collapse after a negative test dose in a patient scheduled for repeat mitral valve surgery.

Near total eclipse of the aortic valve: an echocardiographic penumbra caused by a mechanical mitral valve prosthesis and its clinical implications.

Noble gases without anesthetic properties protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo.

Electroconvulsive therapy-induced asystole: occurrence after 39 previous uneventful treatments.

Management of ileostomy trauma produced by a dog bite in a patient with thoracic paraplegia.

An unusual complication of lumbar subarachnoid drainage catheter placement in a patient undergoing endovascular stent repair of a thoracic aortic aneurysm.

When lack of addition really does add up.

A rare cause of subtotal airway obstruction during anesthetic induction in a patient with facial trauma.

Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection.

[Pseudomembranous supraglottitis with airway compromise in a patient with recurrent tonsillar carcinoma].

Acute pericardial tamponade as a remote complication of a CardioSEAL atrial septal defect closure device.

Progressive dyspnea and exercise intolerance in an adult with a persistent childhood murmur.

Management of hereditary angioedema during off-pump coronary arterial surgery.

Massive retrograde acute type B aortic dissection in a postpartum woman with a family history of Marfan syndrome.

Simvastatin restores ischemic preconditioning in the presence of hyperglycemia through a nitric oxide-mediated mechanism.

Remote right ventricular rupture after coronary artery bypass graft surgery: a catastrophic complication of occult right ventricular infarction in a patient with a sternal infection.

A large, spherical echogenic object appearing in the left atrium during early left ventricular ejection.

An Intracardiac UFO.

Additive cardioprotection by ethanol and sevoflurane: are sarcolemmal K ATP channels also involved?

Intracardiac masses associated with permanent endocardial pacemaker lead erosion through the skin.

Anesthesiology, its mission, and 2007's "best" articles.

Reactive oxygen species and mitochondrial adenosine triphosphate-regulated potassium channels mediate helium-induced preconditioning against myocardial infarction in vivo.

Pretty intraventricular rainbow or convincing evidence for a primary cause of heart failure?

Induction of heat shock protein 70 and preconditioning by sevoflurane: a potent protective interaction against myocardial ischemia-reperfusion injury.

The mechanism of helium-induced preconditioning: a direct role for nitric oxide in rabbits.

Inhibition of glycogen synthase kinase or the apoptotic protein p53 lowers the threshold of helium cardioprotection in vivo: the role of mitochondrial permeability transition.

Gradual development of unilateral Horner's syndrome in an otherwise asymptomatic elderly man. Diagnosis: right upper posterior mediastinal thoracic schwannoma.

Why the "Y"? A peculiar intraventricular structure associated with a posterior basal aneurysm. Diagnosis: isolated calcification of the distal posterior medial papillary muscle.

Progressive dyspnea on exertion in a patient with known coronary artery disease and a remote history of Hodgkin's lymphoma.

A patient with chronic hemodialysis-dependent end-stage renal disease presenting with mild dyspnea on exertion and a harsh systolic murmur.

New rocking motion of a prosthetic aortic valve: an unexpected echocardiographic finding 1 month after implantation.

Recurrent chest pain and dyspnea on exertion in an elderly man: just another case of coronary artery disease or a more unusual cause for "angina"?

Atrial septal thickening in a patient with syncope: variant of lipomatous hypertrophy or cardiac neoplasm?

Sudden onset of sharp left-sided chest pain and hemoptysis in a young man with a history of childhood aortic coarctation repair.

A 2-day history of shortness of breath and intermittent dull substernal chest pain in a 42-year-old man: a case of acute insecticide toxicity or something more ominous?

A mobile threadlike structure in the left atrium: cor triatriatum, artifact, or thrombus?

Incidental discovery of a large right atrial mass in a patient during evaluation for upper abdominal pain.

Case report: delayed presentation of postural headache in an adolescent girl after microscopic lumbar discectomy.

Postconditioning by volatile anesthetics: salvaging ischemic myocardium at reperfusion by activation of prosurvival signaling.

To flow or not to flow: that is the question in this chronic aortic dissection.

Remote exposure to xenon produces delayed preconditioning against myocardial infarction in vivo: additional evidence that noble gases are not biologically inert.

A rare cause of mitral regurgitation in an elderly man undergoing aortic valve replacement.

Perioperative implications of Morquio syndrome in a 31-year-old woman undergoing aortic valve replacement.

Xenon preconditioning: the role of prosurvival signaling, mitochondrial permeability transition and bioenergetics in rats.

Morphine reduces the threshold of helium preconditioning against myocardial infarction: the role of opioid receptors in rabbits.

An object in the proximal left ventricular outflow tract during late diastole: aortic valve prolapse, mass, or normal anatomy?

Ketamine attenuates delirium after cardiac surgery with cardiopulmonary bypass.

A cavity in the left ventricular outflow tract: a disastrous consequence of tooth decay?

Transient metabolic alkalosis during early reperfusion abolishes helium preconditioning against myocardial infarction: restoration of cardioprotection by cyclosporin A in rabbits.

Surgical repair of long-standing mitral valve prolapse: a case report and brief review of the literature.

Severe allergic contact dermatitis resulting from occupational exposure to tincture of benzoin aerosol spray in an anesthesiologist.

Cardioprotection by noble gases.

Case 4--2009. Severe reexpansion pulmonary edema after minimally invasive aortic valve replacement: management using extracorporeal membrane oxygenation.

Anterior chest discomfort and right neck pain in a young woman 2 days after an appendectomy.

Perioperative implications of hereditary spherocytosis in coronary artery surgery.

An elongated oval-shaped echolucent structure centered in the transverse aortic arch: evidence of a vascular disaster or a lucky break?

A simple method for obtaining a "ramped" laryngoscopy position after anesthetic induction.

Neuroprotection by ketamine: a review of the experimental and clinical evidence.

The rings of Saturn in the aortic arch? An unusual consequence of cardiopulmonary bypass in an acute type-A aortic dissection.

Use of ECMO to temporize circulatory instability during severe Brugada electrical storm.

A duplicate middle scallop of the anterior mitral leaflet: benign curiosity, imaging artifact, or important pathology?

Cardioprotection by volatile anesthetics: established scientific principle or lingering clinical uncertainty?

The poppies of Afghanistan.

A rare cause of severe aortic insufficiency without stenosis: certainly not one of the usual suspects.

Cardiac football or cause of severe tricuspid regurgitation?

A history of alcohol dependence increases the incidence and severity of postoperative cognitive dysfunction in cardiac surgical patients.

Successful use of spinal anesthesia in a patient with severe Klippel-Trénaunay syndrome associated with upper airway abnormalities and chronic Kasabach-Merritt coagulopathy.

Another potential anesthetic implication of body piercing.

Postoperative delirium is associated with postoperative cognitive dysfunction at one week after cardiac surgery with cardiopulmonary bypass.

Preoperative dispositional optimism correlates with a reduced incidence of postoperative delirium and recovery of postoperative cognitive function in cardiac surgical patients.

An image from the dark side of the stomach.

Tricuspid regurgitation of varying severity: leaflet prolapse or pacemaker lead-induced obstruction?

History of post-traumatic stress disorder is associated with impaired neuropsychometric performance after coronary artery surgery.

CASE 3-2010 Dynamic partial obstruction of the tricuspid valve inlet produced by anterior mediastinal aspergillosis invading the right atrium.

Facilitating the transition to practice: a weekend retreat curriculum for business-of-medicine education of United States anesthesiology residents.

Feeling the pressure? Anterior mitral leaflet immobility in a patient with bicuspid aortic valve disease.

Postoperative delirium and short-term cognitive dysfunction occur more frequently in patients undergoing valve surgery with or without coronary artery bypass graft surgery compared with coronary artery bypass graft surgery alone: results of a pilot study.

Metabolic syndrome exacerbates short-term postoperative cognitive dysfunction in patients undergoing cardiac surgery: results of a pilot study.

A double-orifice, severely stenotic aortic valve: is leaflet perforation or extensive central calcification with near fusion the culprit?

Dizziness in a patient with a right atrial mass.

A large mass on a newly implanted pulmonary artery catheter: thrombus, vegetation, or an anatomic explanation?

Elevated postoperative inflammatory biomarkers are associated with short- and medium-term cognitive dysfunction after coronary artery surgery.

Delayed cardioprotection by inhaled anesthetics.

Attitudes, patterns of recommendation, and communication of pediatric providers about complementary and alternative medicine in a large metropolitan children's hospital.

A thin structure attached to the atrial septum: what is propping up the tent?

Abnormal fibrillin-1 expression and chronic oxidative stress mediate endothelial mesenchymal transition in a murine model of systemic sclerosis.

Sudden onset of atrial flutter during continuous venovenous hemodialysis.

Persistent chest pain in a polysubstance abuser: an unusual consequence.

Working the angles: continuous cardiac output through Doppler independence.

Sudden cardiac death resulting from acute coronary artery aneurysm occlusion: successful resuscitation and treatment of an adolescent boy with previously unrecognized Kawasaki disease.

Management of labor and delivery of a patient with Von Willebrand disease type 2A.

Postoperative cognitive dysfunction after noncardiac surgery: effects of metabolic syndrome.

Scholarly productivity of united states academic cardiothoracic anesthesiologists: influence of fellowship accreditation and transesophageal echocardiographic credentials on h-index and other citation bibliometrics.

Anterior mitral leaflet injury after debridement?

Who teaches surgical airway management and how do they teach it? A survey of United States anesthesiology training programs.

The mysterious case of an absent true lumen in a patient with a type-A aortic dissection.

Posterior glenohumeral joint dislocation: a rare complication of central venous cannulation in a patient undergoing coronary artery surgery.

Case report: Severe vasospasm mimics hypotension after high-dose intrauterine vasopressin.

Potential adverse ultrasound-related biological effects: a critical review.

Cardiopulmonary bypass transiently inhibits intraventricular vortex ring formation in patients undergoing coronary artery bypass graft surgery.

Bilateral interhemispheric subdural hematoma after inadvertent lumbar puncture in a parturient.

A small circular structure in the right atrium: a cause for right atrial and ventricular dilatation?

A large artery exiting the proximal aortic root: anatomic variation or physiologic compensatory response?

Recent trends in publication of basic science and clinical research by United States investigators in anesthesia journals.

Dizziness leads to an unexpected diagnosis.

Comparison of pre-existing cognitive impairment, amnesic mild cognitive impairment, and multiple domain mild cognitive impairment in men scheduled for coronary artery surgery.

Recurrent polymorphic ventricular tachycardia: the real thing or a soapy explanation?

A bibliometric analysis of geographic publication variations in the Journal of Cardiothoracic and Vascular Anesthesia from 1990 to 2011.

Transient repetitive exposure to low level light therapy enhances collateral blood vessel growth in the ischemic hindlimb of the tight skin mouse.

4F decreases IRF5 expression and activation in hearts of tight skin mice.

An echogenic object in the left atrium: a consequence of end-stage renal disease?

Myocardial protection by volatile anesthetics in patients undergoing cardiac surgery: a critical review of the laboratory and clinical evidence.

The ascending thoracic aorta stages a vanishing act?

Massive pulmonary thromboembolism complicating acute type-a aortic dissection or another explanation for right ventricular dilatation?

Chronic pressure-overload hypertrophy attenuates vortex formation time in patients with severe aortic stenosis and preserved left ventricular systolic function undergoing aortic valve replacement.

Hematemesis and free air under the diaphragm: just another perforated duodenal ulcer or something more unusual?

Anesthetic implications of emergent Cesarean section in a parturient with Noonan syndrome and bacterial endocarditis.

Is a dissection in the middle of the aortic arch complicating this large ascending thoracic aortic aneurysm?

Left ventricular "masses" in a patient with protein S deficiency and a recent myocardial infarction: evidence of intraventricular thrombi or a benign observation?

A heart with six chambers: a remarkable anomaly or a late complication after cardiac surgery?

Mechanism of torrential regurgitation in mitral valve endocarditis: the usual chordal rupture-leaflet flail or another more dramatic structural defect?

New regurgitation after aortic valve replacement with a stented bovine pericardial prosthesis: is the leak paravalvular or non-paravalvular?

A heart in the heart.

Safety, tolerability, and short-term efficacy of intravenous lidocaine infusions for the treatment of chronic pain in adolescents and young adults: a preliminary report.

An unusual cause of severe mitral regurgitation in a patient with aortic valve endocarditis.

A widened mediastinum in an asymptomatic man with a remote history of repaired type-A aortic dissection.

New complex mitral regurgitation after aortic valve replacement: iatrogenic injury or simple explanation?

Why the new severe aortic insufficiency after mitral and tricuspid valve repair?

The Prevention of Delirium and Complications Associated with Surgical Treatments (PODCAST) study: protocol for an international multicentre randomised controlled trial.

Aortic valve replacement reduces valvuloarterial impedance but does not affect systemic arterial compliance in elderly men with degenerative calcific trileaflet aortic valve stenosis.

Use of multimodal imaging in the management of tumor embolism from the inferior vena cava through the right heart in a patient with renal cell carcinoma.

Double-barrel proximal thoracic aorta or horrific complication of endocarditis?

Utility of preoperative anesthesia clinic videoendoscopy for airway management planning.

Remote ischemic preconditioning prevents deterioration of short-term postoperative cognitive function after cardiac surgery using cardiopulmonary bypass: results of a pilot investigation.

"Air" in the aortic arch after cannulation for cardiopulmonary bypass: devastating complication or benign explanation?

"Unicuspid" aortic valve bioprosthesis: a complication of surgery for a left hip Morel-Lavallée lesion?

Edible model of mitral valve leaflet surface geometry.

How Can a Large Left Atrial Myxoma Cause a Selective Mid-Diastolic Right-to-Left Atrial Shunt?

An unlikely cause of a new diastolic murmur heard during a routine employment physical exam.

"Robo-tripping": dextromethorphan abuse and its anesthetic implications.

Pneumonia and Inflammatory Arthritis Caused by Unusual Occupational Exposure or a Life-Threatening Infection Resulting From a More Commonly Encountered Mechanism?

Scholarly productivity and national institutes of health funding of foundation for anesthesia education and research grant recipients: insights from a bibliometric analysis.

Narrow, Highly Mobile Structure in the Right Atrium: Large Eustachian Valve, Prominent Chiari Network, Thrombus, Vegetation, or Flail Tricuspid Chordae Tendineae?

Anesthesia Preoperative Clinic Referral for Elevated Hba1c Reduces Complication Rate in Diabetic Patients Undergoing Total Joint Arthroplasty.

Mechanism of Torrential Aortic Valve Insufficiency in Endocarditis: Leaflet Destruction, Restriction, Prolapse, or Perforation?

A Highly Mobile Mass in the Anterior Left Ventricular Outflow Tract Immediately Beneath a Heavily Calcified, Stenotic Aortic Valve: Vegetation, Thrombus, or Neoplasm?

Response to Proposed Mechanism for "Air" in the Aorta.

Anesthetic "Conditioning:" A Continuing Question of Clinical Relevance.

Letter in Reply.

Unusual Flap-Like Linear Echogenic Structure in the Posterior Right Atrium Above the Tricuspid Valve Septal Leaflet.

An Unusual Cause for New Right Bundle-Branch Block.

A Scientist-Skeptic-Agnostic's View of the Church of Anesthetic Cardioprotection.

Acute, Severe Chest Pain in the Presence of Known Coronary Artery Disease: New Myocardial Ischemia, Aortic Dissection, or Some Other Evolving Cardiovascular Catastrophe?

An IRF5 Decoy Peptide Reduces Myocardial Inflammation and Fibrosis and Improves Endothelial Cell Function in Tight-Skin Mice.

Preoperative Troponin in Patients Undergoing Noncardiac Surgery: Is Timing Everything?

Use of Oral Droxidopa to Improve Arterial Pressure and Reduce Vasoactive Drug Requirements During Persistent Vasoplegic Syndrome After Cardiac Transplantation.

Rare Cause of Chest Discomfort and Modest Exercise Intolerance in an Athlete.

Anesthetic Considerations of Sporadic Inclusion Body Myositis in an Elderly Man With Orthopedic Trauma.

Response to Letter about the Thebesian Valve.

Acute, Severe Pulmonary Arterial Hypertension During Off-Pump Coronary Artery Surgery: Is New Myocardial Ischemia, Cardiac Repositioning, or External Mitral Valve Compression the Culprit?

Moderate Aortic Valvular Insufficiency Invalidates Vortex Formation Time as an Index of Left Ventricular Filling Efficiency in Patients With Severe Degenerative Calcific Aortic Stenosis Undergoing Aortic Valve Replacement.

Noninvasively Measured Hemoglobin Concentration Reflects Arterial Hemoglobin Concentration Before but Not After Cardiopulmonary Bypass in Patients Undergoing Coronary Artery or Valve Surgery.

Demographics and Scholarly Productivity of American Board of Anesthesiology Volunteers: Results of an Internet-Based Bibliometric Analysis.

A Pulmonary Venous Blood Flow Problem During Left Upper Lobectomy.

A Rare Cause of Exercise Intolerance and Progressive Dyspnea in an Elderly Woman.

A Rare Complication of Cardiopulmonary Resuscitation After Mitral Valve Replacement.

Short-Term Angiotensin Subtype 1 Receptor Blockade Does Not Alter the Circulatory Responses to Sympathetic Nervous System Modulation in Healthy Volunteers Before and During Sevoflurane Anesthesia: Results of a Pilot Study.

Serotonin Syndrome Resulting From Acute Decompensation of Nonalcoholic Steatohepatitis Cirrhosis in a Patient Chronically Treated With Citalopram and Tramadol.

Hydroxocobalamin as a Rescue Treatment for Refractory Vasoplegic Syndrome After Prolonged Cardiopulmonary Bypass.

Acute Severe Thrombocytopenia Occurring After Administration of Eptifibatide Postpones Emergent Coronary Artery Surgery.

Treatment of Vasoplegic Syndrome With Intravenous Hydroxocobalamin During Liver Transplantation: A Report of 2 Cases.

A Rare Complication of Metastatic Osteosarcoma.

Profound Hypotension After Anesthetic Induction in an Elderly Man With a Large Ascending Aortic Aneurysm: The Usual Anesthetic-Induced Vasodilation or a More Uncommon Mechanism?

Moderate, Short-Term, Local Hyperglycemia Attenuates Forearm Endothelium-Dependent Vasodilation After Transient Ischemia-Reperfusion in Human Volunteers.

An Unanticipated Airway Problem in a Man Undergoing Femoral-Popliteal Bypass.

Continuous Blood Flow in the Distal Right Sinus of Valsalva After Aortic Valve Replacement: Bioprosthetic Valve Dysfunction, Paravalvular Leak, Iatrogenic Damage, or Another Cause?

Persistent Hypotension and Cerebral Swelling Resulting From Mesenteric Traction Syndrome After Omental-to-Pial Pedicle Flap Transfer in a Young Woman With Refractory Moyamoya Disease: A Case Report.

An Unexpected Finding During Repair of An Ascending Aortic Aneurysm.

An Unusual Finding in a Woman Undergoing Resection of a Large Anterior Mediastinal Mass.

Hydroxocobalamin With or Without Methylene Blue May Improve Fluid Balance in Critically Ill Patients With Vasoplegic Syndrome After Cardiac Surgery: A Report of Two Cases.

An Unusual Cause of an Isolated Transient Ischemic Attack in an Otherwise Healthy Elderly Man.

Progressive Dyspnea in a Man With Recently Treated Presumed Endocarditis: The Usual Onset of Valvular Incompetence or More Complex Pathology?

Right Ventricular Perfusion: Physiology and Clinical Implications.

A Rare Cause of Intermittent Dyspnea, Occasional Palpitations, and Atypical Chest Discomfort.

Unexpected Findings in a Man with a Repaired Type A Aortic Dissection and a New Stroke.

The Discovery of Myocardial Preconditioning Using Volatile Anesthetics: A History and Contemporary Clinical Perspective.

An Alternative Technique for Radial Arterial Catheterization.

Advanced Age Attenuates Left Ventricular Filling Efficiency Quantified Using Vortex Formation Time: A Study of Octogenarians With Normal Left Ventricular Systolic Function Undergoing Coronary Artery Surgery.

Acute Onset of Severe Chest Pain Associated With Strenuous Sexual Activity.

An Unexpected Finding During Aortic Valve Replacement and Coronary Artery Surgery.

Anesthesia Preoperative Clinic Evaluation of Obstructive Sleep Apnea Using Nasal Fiberoptic Videoendoscopy: A Pilot Study Comparison with Polysomnography.

Propofol and Remote Ischemic Preconditioning: Possible Implications for Studies of Clinical Myocardial Protection Using Volatile Anesthetics in Cardiac Surgery Patients?

Perioperative Management of a Large Idiopathic Pulmonary Artery Aneurysm Without Pulmonary Arterial Hypertension.

Selective Partial Obstruction of Inferior Vena Cava Blood Flow During Diastole: Cor Triatriatum Dexter, Large Eustachian Valve, or Chiari Network?

An Unanticipated Airway Finding After Orotracheal Intubation With a GlideScope Videolaryngoscope.

A Rare Cause of Stroke FourWeeks After Ascending Aortic Aneurysm Repair.

Progressive Increase in Scholarly Productivity of New American Board of Anesthesiology Diplomates From 2006 to 2016: A Bibliometric Analysis.

Larson's Maneuver to Facilitate Endotracheal Intubation Using Videolaryngoscopy.