Department of Bioengineering
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Stability of the hybrid epithelial/mesenchymal phenotype.
Oncotarget Mar, 2016 | Pubmed ID: 27008704
Establishing direction during chemotaxis in eukaryotic cells.
Biophysical journal Sep, 2002 | Pubmed ID: 12202361
Mode-I fracture in a nonlinear lattice with viscoelastic forces.
Physical review. E, Statistical, nonlinear, and soft matter physics Jul, 2002 | Pubmed ID: 12241445
Spectral mixing of rhythmic neuronal signals in sensory cortex.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2002 | Pubmed ID: 12403828
Comment on "dynamics of HIV infection: a cellular automata approach".
Physical review letters Nov, 2002 | Pubmed ID: 12443459
Dynamics of competitive evolution on a smooth landscape.
Physical review letters Feb, 2003 | Pubmed ID: 12633464
Coupled map lattice techniques for simulating interfacial phenomena in reaction-diffusion systems.
Chaos (Woodbury, N.Y.) Jul, 1992 | Pubmed ID: 12779983
Modeling spatial patterns in Dictyostelium.
Chaos (Woodbury, N.Y.) Sep, 1994 | Pubmed ID: 12780133
Wave nucleation rate in excitable systems in the low noise limit.
Physical review. E, Statistical, nonlinear, and soft matter physics Sep, 2003 | Pubmed ID: 14524810
Does the continuum theory of dynamic fracture work?
Physical review. E, Statistical, nonlinear, and soft matter physics Sep, 2003 | Pubmed ID: 14524843
Shunting inhibition controls the gain modulation mediated by asynchronous neurotransmitter release in early development.
PLoS computational biology Nov, 2010 | Pubmed ID: 21079676
Computational approach for modeling intra- and extracellular dynamics.
Physical review. E, Statistical, nonlinear, and soft matter physics Sep, 2003 | Pubmed ID: 14524934
Analytical study of the effect of recombination on evolution via DNA shuffling.
Physical review. E, Statistical, nonlinear, and soft matter physics May, 2004 | Pubmed ID: 15244851
Bacterial linguistic communication and social intelligence.
Trends in microbiology Aug, 2004 | Pubmed ID: 15276612
Domain swapping is a consequence of minimal frustration.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2004 | Pubmed ID: 15361578
Dynamic instabilities of fracture under biaxial strain using a phase field model.
Physical review letters Sep, 2004 | Pubmed ID: 15447417
Recombination dramatically speeds up evolution of finite populations.
Physical review letters Mar, 2005 | Pubmed ID: 15784005
Fluctuation-regularized front propagation dynamics in reaction-diffusion systems.
Physical review letters Apr, 2005 | Pubmed ID: 15904196
Protein oligomerization through domain swapping: role of inter-molecular interactions and protein concentration.
Journal of molecular biology Sep, 2005 | Pubmed ID: 16061250
Excitation-contraction coupling gain and cooperativity of the cardiac ryanodine receptor: a modeling approach.
Biophysical journal Nov, 2005 | Pubmed ID: 16126827
Physical schemata underlying biological pattern formation-examples, issues and strategies.
Physical biology Jun, 2004 | Pubmed ID: 16204813
Cooperativity can reduce stochasticity in intracellular calcium dynamics.
Physical biology Jun, 2004 | Pubmed ID: 16204819
Structure of infectious prions: stabilization by domain swapping.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov, 2005 | Pubmed ID: 16260647
Division accuracy in a stochastic model of Min oscillations in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2006 | Pubmed ID: 16387859
Membrane-bound Turing patterns.
Physical review. E, Statistical, nonlinear, and soft matter physics Dec, 2005 | Pubmed ID: 16485979
Front propagation up a reaction rate gradient.
Physical review. E, Statistical, nonlinear, and soft matter physics Dec, 2005 | Pubmed ID: 16486029
Analytic approach to the evolutionary effects of genetic exchange.
Physical review. E, Statistical, nonlinear, and soft matter physics Jan, 2006 | Pubmed ID: 16486222
Directional sensing in eukaryotic chemotaxis: a balanced inactivation model.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2006 | Pubmed ID: 16782813
Embryonic pattern scaling achieved by oppositely directed morphogen gradients.
Physical biology May, 2006 | Pubmed ID: 16829697
Self-engineering capabilities of bacteria.
Journal of the Royal Society, Interface / the Royal Society Feb, 2006 | Pubmed ID: 16849231
Fluctuation-induced instabilities in front propagation up a comoving reaction gradient in two dimensions.
Physical review. E, Statistical, nonlinear, and soft matter physics Jul, 2006 | Pubmed ID: 16907163
Effective stochastic dynamics on a protein folding energy landscape.
The Journal of chemical physics Aug, 2006 | Pubmed ID: 16942260
The astrocyte as a gatekeeper of synaptic information transfer.
Neural computation Feb, 2007 | Pubmed ID: 17206866
Quantifying noise levels of intercellular signals.
Physical review. E, Statistical, nonlinear, and soft matter physics Jun, 2007 | Pubmed ID: 17677298
Folding time predictions from all-atom replica exchange simulations.
Journal of molecular biology Sep, 2007 | Pubmed ID: 17681536
Target-specific and global effectors in gene regulation by MicroRNA.
Biophysical journal Dec, 2007 | Pubmed ID: 17872959
Correlated phenotypic transitions to competence in bacterial colonies.
Physical review. E, Statistical, nonlinear, and soft matter physics Oct, 2007 | Pubmed ID: 17994927
Small regulatory RNAs may sharpen spatial expression patterns.
PLoS computational biology Nov, 2007 | Pubmed ID: 18052540
Astrocytes optimize the synaptic transmission of information.
PLoS computational biology May, 2008 | Pubmed ID: 18516277
Coexistence of amplitude and frequency modulations in intracellular calcium dynamics.
Physical review. E, Statistical, nonlinear, and soft matter physics Mar, 2008 | Pubmed ID: 18517322
Activity-dependent stochastic resonance in recurrent neuronal networks.
Physical review. E, Statistical, nonlinear, and soft matter physics Jun, 2008 | Pubmed ID: 18643209
Receptor noise and directional sensing in eukaryotic chemotaxis.
Physical review letters Jun, 2008 | Pubmed ID: 18643461
Multimodal encoding in a simplified model of intracellular calcium signaling.
Cognitive processing Feb, 2009 | Pubmed ID: 19030904
Receptor noise limitations on chemotactic sensing.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2008 | Pubmed ID: 19064934
A mathematical analysis of second messenger compartmentalization.
Physical biology Dec, 2008 | Pubmed ID: 19075354
The fixation probability of rare mutators in finite asexual populations.
Genetics Apr, 2009 | Pubmed ID: 19153261
Determining the scale of the Bicoid morphogen gradient.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2009 | Pubmed ID: 19190186
Mechanisms and constraints on yeast MAPK signaling specificity.
Biophysical journal Jun, 2009 | Pubmed ID: 19527636
Locally balanced dendritic integration by short-term synaptic plasticity and active dendritic conductances.
Journal of neurophysiology Dec, 2009 | Pubmed ID: 19759328
Signal processing in local neuronal circuits based on activity-dependent noise and competition.
Chaos (Woodbury, N.Y.) Sep, 2009 | Pubmed ID: 19791987
Compartmentalization of second messengers in neurons: a mathematical analysis.
Physical review. E, Statistical, nonlinear, and soft matter physics Oct, 2009 | Pubmed ID: 19905336
Phenomenological approach to eukaryotic chemotactic efficiency.
Physical review. E, Statistical, nonlinear, and soft matter physics Mar, 2010 | Pubmed ID: 20365769
External and internal constraints on eukaryotic chemotaxis.
Proceedings of the National Academy of Sciences of the United States of America May, 2010 | Pubmed ID: 20457897
Transient localized patterns in noise-driven reaction-diffusion systems.
Physical review letters Apr, 2010 | Pubmed ID: 20482022
A comparison of deterministic and stochastic simulations of neuronal vesicle release models.
Physical biology May, 2010 | Pubmed ID: 20505227
The role of cell contraction and adhesion in dictyostelium motility.
Biophysical journal Jul, 2010 | Pubmed ID: 20655832
Optimal strategy for competence differentiation in bacteria.
PLoS genetics Sep, 2010 | Pubmed ID: 20838595
Computational model for cell morphodynamics.
Physical review letters Sep, 2010 | Pubmed ID: 20867552
Physical limits on cellular sensing of spatial gradients.
Physical review letters Jul, 2010 | Pubmed ID: 20867888
Gradient sensing in defined chemotactic fields.
Integrative biology : quantitative biosciences from nano to macro Nov, 2010 | Pubmed ID: 20882228
Modelling vesicular release at hippocampal synapses.
PLoS computational biology Nov, 2010 | Pubmed ID: 21085682
Design principles and specificity in biological networks with cross activation.
Physical biology Apr, 2011 | Pubmed ID: 21263168
How geometry and internal bias affect the accuracy of eukaryotic gradient sensing.
Physical review. E, Statistical, nonlinear, and soft matter physics Feb, 2011 | Pubmed ID: 21405873
Quantifying information transmission in eukaryotic gradient sensing and chemotactic response.
Journal of statistical physics Apr, 2011 | Pubmed ID: 21643513
Activated membrane patches guide chemotactic cell motility.
PLoS computational biology Jun, 2011 | Pubmed ID: 21738453
"Self-assisted" amoeboid navigation in complex environments.
PloS one , 2011 | Pubmed ID: 21829602
Propagating mode-I fracture in amorphous materials using the continuous random network model.
Physical review. E, Statistical, nonlinear, and soft matter physics Aug, 2011 | Pubmed ID: 21929059
Effects of input noise on a simple biochemical switch.
Physical review letters Sep, 2011 | Pubmed ID: 22107236
Incoherent feedforward control governs adaptation of activated ras in a eukaryotic chemotaxis pathway.
Science signaling Jan, 2012 | Pubmed ID: 22215733
Noise effects in nonlinear biochemical signaling.
Physical review. E, Statistical, nonlinear, and soft matter physics Jan, 2012 | Pubmed ID: 22400585
Coupling actin flow, adhesion, and morphology in a computational cell motility model.
Proceedings of the National Academy of Sciences of the United States of America May, 2012 | Pubmed ID: 22493219
Bacterial survival strategies suggest rethinking cancer cooperativity.
Trends in microbiology Sep, 2012 | Pubmed ID: 22750098
Short-term plasticity constrains spatial organization of a hippocampal presynaptic terminal.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2012 | Pubmed ID: 22908295
Alignment of cellular motility forces with tissue flow as a mechanism for efficient wound healing.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2013 | Pubmed ID: 23345440
How input fluctuations reshape the dynamics of a biological switching system.
Physical review. E, Statistical, nonlinear, and soft matter physics Dec, 2012 | Pubmed ID: 23367979
Large population solution of the stochastic Luria-Delbruck evolution model.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2013 | Pubmed ID: 23818583
Energy evaluation of β-strand packing in a fibril-forming SH3 domain.
The journal of physical chemistry. B Oct, 2013 | Pubmed ID: 23819485
We need theoretical physics approaches to study living systems.
Physical biology Aug, 2013 | Pubmed ID: 23883648
Scientific priorities for the BRAIN Initiative.
Nature methods Aug, 2013 | Pubmed ID: 23900253
MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2013 | Pubmed ID: 24154725
Periodic migration in a physical model of cells on micropatterns.
Physical review letters Oct, 2013 | Pubmed ID: 24160631
Modeling cell-death patterning during biofilm formation.
Physical biology Dec, 2013 | Pubmed ID: 24275528
Growth feedback as a basis for persister bistability.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2014 | Pubmed ID: 24344277
The physics of eukaryotic chemotaxis.
Physics today Feb, 2013 | Pubmed ID: 24363460
Toward rationally redesigning bacterial two-component signaling systems using coevolutionary information.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2014 | Pubmed ID: 24449878
Physical Biology : challenges for our second decade.
Physical biology Jun, 2014 | Pubmed ID: 24732666
Intercellular stress reconstitution from traction force data.
Biophysical journal Aug, 2014 | Pubmed ID: 25099794
Introduction to physics in cancer research.
Cancer research Sep, 2014 | Pubmed ID: 25183782
Resistance to chemotherapy: patient variability and cellular heterogeneity.
Cancer research Sep, 2014 | Pubmed ID: 25183790
Cellular memory in eukaryotic chemotaxis.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2014 | Pubmed ID: 25249632
Polarity mechanisms such as contact inhibition of locomotion regulate persistent rotational motion of mammalian cells on micropatterns.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2014 | Pubmed ID: 25258412
Learning physics of living systems from Dictyostelium.
Physical biology Oct, 2014 | Pubmed ID: 25294248
How input noise limits biochemical sensing in ultrasensitive systems.
Physical review. E, Statistical, nonlinear, and soft matter physics Sep, 2014 | Pubmed ID: 25314468
Towards elucidating the connection between epithelial-mesenchymal transitions and stemness.
Journal of the Royal Society, Interface / the Royal Society Dec, 2014 | Pubmed ID: 25339690
Connecting thermal and mechanical protein (un)folding landscapes.
Biophysical journal Dec, 2014 | Pubmed ID: 25517160
Mechanically-driven phase separation in a growing bacterial colony.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2015 | Pubmed ID: 25870260
OVOL guides the epithelial-hybrid-mesenchymal transition.
Oncotarget Jun, 2015 | Pubmed ID: 25944618
Alignment and nonlinear elasticity in biopolymer gels.
Physical review. E, Statistical, nonlinear, and soft matter physics Apr, 2015 | Pubmed ID: 25974530
Properties of cooperatively induced phases in sensing models.
Physical review. E, Statistical, nonlinear, and soft matter physics May, 2015 | Pubmed ID: 26066199
Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis.
Frontiers in oncology , 2015 | Pubmed ID: 26258068
Coupling the modules of EMT and stemness: A tunable 'stemness window' model.
Oncotarget Sep, 2015 | Pubmed ID: 26317796
Micromechanics of cellularized biopolymer networks.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2015 | Pubmed ID: 26324923
The motility-proliferation-metabolism interplay during metastatic invasion.
Scientific reports Sep, 2015 | Pubmed ID: 26337223
Nonlinear elasticity of disordered fiber networks.
Soft matter Feb, 2016 | Pubmed ID: 26616428
Excitable waves and direction-sensing in Dictyostelium discoideum: steps towards a chemotaxis model.
Physical biology Jan, 2016 | Pubmed ID: 26824302
Modeling closure of circular wounds through coordinated collective motion.
Physical biology Feb, 2016 | Pubmed ID: 26871883
Scaling solution in the large population limit of the general asymmetric stochastic Luria-Delbrück evolution process.
Journal of statistical physics Feb, 2015 | Pubmed ID: 26900175
Contact inhibition of locomotion determines cell-cell and cell-substrate forces in tissues.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2016 | Pubmed ID: 26903658
Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2016 | Pubmed ID: 26929325
Emergent Collective Chemotaxis without Single-Cell Gradient Sensing.
Physical review letters Mar, 2016 | Pubmed ID: 26991203
Tumor Budding: The Name is EMT. Partial EMT.
Journal of clinical medicine Apr, 2016 | Pubmed ID: 27136592
Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype.
Journal of the Royal Society, Interface May, 2016 | Pubmed ID: 27170649
Collective Signal Processing in Cluster Chemotaxis: Roles of Adaptation, Amplification, and Co-attraction in Collective Guidance.
PLoS computational biology Jul, 2016 | Pubmed ID: 27367541
Mesenchymal-Epithelial Transition in Sarcomas Is Controlled by the Combinatorial Expression of MicroRNA 200s and GRHL2.
Molecular and cellular biology Oct, 2016 | Pubmed ID: 27402864
Phenotypic plasticity in prostate cancer: role of intrinsically disordered proteins.
Asian journal of andrology Sep-Oct, 2016 | Pubmed ID: 27427552
Expanding the scale of molecular biophysics.
Physical biology Oct, 2016 | Pubmed ID: 27716638
Modeling delayed processes in biological systems.
Physical review. E Sep, 2016 | Pubmed ID: 27739721
Mechanical bounds to transcriptional noise.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2016 | Pubmed ID: 27911801
Modeling the Genetic Regulation of Cancer Metabolism: Interplay between Glycolysis and Oxidative Phosphorylation.
Cancer research Feb, 2017 | Pubmed ID: 28202516
Crawling and turning in a minimal reaction-diffusion cell motility model: Coupling cell shape and biochemistry.
Physical review. E Jan, 2017 | Pubmed ID: 28208438
The GRHL2/ZEB Feedback Loop - A Key Axis in the Regulation of EMT in Breast Cancer.
Journal of cellular biochemistry Mar, 2017 | Pubmed ID: 28266048
Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2017 | Pubmed ID: 28289210
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