Christian Grillon

Benzodiazepines have no effect on fear-potentiated startle in humans.

Associative learning deficits increase symptoms of anxiety in humans.

Startle reactivity and anxiety disorders: aversive conditioning, context, and neurobiology.

Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans.

Emotional arousal does not affect delay eyeblink conditioning.

A review of the modulation of the startle reflex by affective states and its application in psychiatry.

Effects of the beta-blocker propranolol on cued and contextual fear conditioning in humans.

A neuroimaging method for the study of threat in adolescents.

Adaptive and maladaptive psychobiological responses to severe psychological stress: implications for the discovery of novel pharmacotherapy.

Fear conditioning in virtual reality contexts: a new tool for the study of anxiety.

Anxious responses to predictable and unpredictable aversive events.

Deficits in hippocampus-mediated Pavlovian conditioning in endogenous hypercortisolism.

Airpuff startle probes: an efficacious and less aversive alternative to white-noise.

Families at high and low risk for depression: a 3-generation study.

Electroencephalographic measures of regional hemispheric activity in offspring at risk for depressive disorders.

An investigation of prepulse inhibition in pediatric bipolar disorder.

Families at high and low risk for depression: a three-generation startle study.

Classical fear conditioning in the anxiety disorders: a meta-analysis.

Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder.

Cortisol and DHEA-S are associated with startle potentiation during aversive conditioning in humans.

Hydrocortisone impairs hippocampal-dependent trace eyeblink conditioning in post-traumatic stress disorder.

Anticipation of public speaking in virtual reality reveals a relationship between trait social anxiety and startle reactivity.

The strong situation: a potential impediment to studying the psychobiology and pharmacology of anxiety disorders.

Sensation seeking and the aversive motivational system.

Brainstem correlates of defensive states in humans.

Using affect-modulated startle to study phenotypes of pediatric bipolar disorder.

The benzodiazepine alprazolam dissociates contextual fear from cued fear in humans as assessed by fear-potentiated startle.

Context conditioning and behavioral avoidance in a virtual reality environment: effect of predictability.

Attentional blink and prepulse inhibition of startle are positively correlated.

A single dose of the selective serotonin reuptake inhibitor citalopram exacerbates anxiety in humans: a fear-potentiated startle study.

Reduction of trace but not delay eyeblink conditioning in panic disorder.

Luteal-phase accentuation of acoustic startle response in women with premenstrual dysphoric disorder.

Contextual-specificity of short-delay extinction in humans: renewal of fear-potentiated startle in a virtual environment.

Sensitivity to masked conditioned stimuli predicts conditioned response magnitude under masked conditions.

Acute exposure to stress improves performance in trace eyeblink conditioning and spatial learning tasks in healthy men.

Comments on Fearful and sexual pictures not consciously seen modulate the startle reflex in human beings.

Fear-potentiated startle to threat, and prepulse inhibition among young adult nonsmokers, abstinent smokers, and nonabstinent smokers.

Cerebral blood flow in immediate and sustained anxiety.

Neural responses to auditory stimulus deviance under threat of electric shock revealed by spatially-filtered magnetoencephalography.

Startle potentiation in rapidly alternating conditions of high and low predictability of threat.

Emotion regulation and potentiated startle across affective picture and threat-of-shock paradigms.

Acute stress potentiates anxiety in humans.

Elevated fear conditioning to socially relevant unconditioned stimuli in social anxiety disorder.

Models and mechanisms of anxiety: evidence from startle studies.

Fear conditioning in adolescents with anxiety disorders: results from a novel experimental paradigm.

Increased anxiety during anticipation of unpredictable but not predictable aversive stimuli as a psychophysiologic marker of panic disorder.

It is time to take a stand for medical research and against terrorism targeting medical scientists.

Generalization of conditioned fear-potentiated startle in humans: experimental validation and clinical relevance.

Contextual specificity of extinction of delay but not trace eyeblink conditioning in humans.

Human hippocampal and parahippocampal theta during goal-directed spatial navigation predicts performance on a virtual Morris water maze.

Greater sustained anxiety but not phasic fear in women compared to men.

Contextual fear conditioning in humans: cortical-hippocampal and amygdala contributions.

Modality-specific attention under imminent but not remote threat of shock: evidence from differential prepulse inhibition of startle.

Two-week treatment with the selective serotonin reuptake inhibitor citalopram reduces contextual anxiety but not cued fear in healthy volunteers: a fear-potentiated startle study.

Increased anterior cingulate cortical activity in response to fearful faces: a neurophysiological biomarker that predicts rapid antidepressant response to ketamine.

Evoked amygdala responses to negative faces revealed by adaptive MEG beamformers.

Startle reactivity in children at risk for migraine.

Impaired discriminative fear-conditioning resulting from elevated fear responding to learned safety cues among individuals with panic disorder.

Increased anxiety during anticipation of unpredictable aversive stimuli in posttraumatic stress disorder but not in generalized anxiety disorder.

Working memory performance after acute exposure to the cold pressor stress in healthy volunteers.

Startle response in behaviorally inhibited adolescents with a lifetime occurrence of anxiety disorders.

D-cycloserine facilitation of fear extinction and exposure-based therapy might rely on lower-level, automatic mechanisms.

Impaired spatial navigation in pediatric anxiety.

Phasic vs sustained fear in rats and humans: role of the extended amygdala in fear vs anxiety.

Overgeneralization of conditioned fear as a pathogenic marker of panic disorder.

Anterior cingulate desynchronization and functional connectivity with the amygdala during a working memory task predict rapid antidepressant response to ketamine.

Abnormal hippocampal functioning and impaired spatial navigation in depressed individuals: evidence from whole-head magnetoencephalography.

Effect of acute psychological stress on prefrontal GABA concentration determined by proton magnetic resonance spectroscopy.

Development of anxiety: the role of threat appraisal and fear learning.

Becoming the center of attention in social anxiety disorder: startle reactivity to a virtual audience during speech anticipation.

Phasic and sustained fear in humans elicits distinct patterns of brain activity.

Acute hydrocortisone treatment increases anxiety but not fear in healthy volunteers: a fear-potentiated startle study.

Distinct neural signatures of threat learning in adolescents and adults.

Anxiety overrides the blocking effects of high perceptual load on amygdala reactivity to threat-related distractors.

Measuring anxious responses to predictable and unpredictable threat in children and adolescents.

The effect of induced anxiety on cognition: threat of shock enhances aversive processing in healthy individuals.

In the face of fear: anxiety sensitizes defensive responses to fearful faces.

The adaptive threat bias in anxiety: amygdala-dorsomedial prefrontal cortex coupling and aversive amplification.

Anxiety, a benefit and detriment to cognition: behavioral and magnetoencephalographic evidence from a mixed-saccade task.

Describing the interplay between anxiety and cognition: from impaired performance under low cognitive load to reduced anxiety under high load.

Testing the effects of Δ9-THC and D-cycloserine on extinction of conditioned fear in humans.

Assessing fear and anxiety in humans using the threat of predictable and unpredictable aversive events (the NPU-threat test).

Through the eyes of anxiety: Dissecting threat bias via emotional-binocular rivalry.

Distinct contributions of human hippocampal theta to spatial cognition and anxiety.

Acute tryptophan depletion increases translational indices of anxiety but not fear: serotonergic modulation of the bed nucleus of the stria terminalis?

Synaptic potentiation is critical for rapid antidepressant response to ketamine in treatment-resistant major depression.

Enhanced discrimination between threatening and safe contexts in high-anxious individuals.

Stress increases aversive prediction error signal in the ventral striatum.

Passive avoidance is linked to impaired fear extinction in humans.

The impact of induced anxiety on response inhibition.

The complex interaction between anxiety and cognition: insight from spatial and verbal working memory.

The role of serotonin in the neurocircuitry of negative affective bias: serotonergic modulation of the dorsal medial prefrontal-amygdala 'aversive amplification' circuit.

The impact of anxiety upon cognition: perspectives from human threat of shock studies.

Neural substrates of classically conditioned fear-generalization in humans: a parametric fMRI study.

Response to learned threat: An FMRI study in adolescent and adult anxiety.

Major depression is not associated with blunting of aversive responses; evidence for enhanced anxious anticipation.

Generalized anxiety disorder is associated with overgeneralization of classically conditioned fear.

Developmental investigation of fear-potentiated startle across puberty.

Evidence of MAOA genotype involvement in spatial ability in males.

Increased fear-potentiated startle in major depressive disorder patients with lifetime history of suicide attempt.

Understanding placebo and nocebo responses for pain management.

Sustained anxiety increases amygdala-dorsomedial prefrontal coupling: a mechanism for maintaining an anxious state in healthy adults.

Pain and placebo in pediatrics: a comprehensive review of laboratory and clinical findings.

The CRH1 antagonist GSK561679 increases human fear but not anxiety as assessed by startle.

Oxytocin and vasopressin modulate risk-taking.

fMRI functional connectivity applied to adolescent neurodevelopment.

Mental fatigue impairs emotion regulation.

Towards a mechanistic understanding of pathological anxiety: the dorsal medial prefrontal-amygdala 'aversive amplification' circuit in unmedicated generalized and social anxiety disorders.

Effect of attention control on sustained attention during induced anxiety.

Resting state connectivity of the bed nucleus of the stria terminalis at ultra-high field.

Vasopressin Boosts Placebo Analgesic Effects in Women: A Randomized Trial.

Effect of anxiety on behavioural pattern separation in humans.

Interaction of threat and verbal working memory in adolescents.

Age and Social Context Modulate the Effect of Anxiety on Risk-taking in Pediatric Samples.

Abnormal decision-making in generalized anxiety disorder: Aversion of risk or stimulus-reinforcement impairment?

Induced-anxiety differentially disrupts working memory in generalized anxiety disorder.

Anxiety Patients Show Reduced Working Memory Related dlPFC Activation During Safety and Threat.

Striatum on the anxiety map: Small detours into adolescence.

The neural basis of improved cognitive performance by threat of shock.

Working memory maintenance is sufficient to reduce state anxiety.

The effects of methylphenidate and propranolol on the interplay between induced-anxiety and working memory.

Gain in Translation: Is It Time for Thigmotaxis Studies in Humans?

Prediction Error Representation in Individuals With Generalized Anxiety Disorder During Passive Avoidance.

Altered Pain Perception and Fear-Learning Deficits in Subjects With Posttraumatic Stress Disorder.

Anxiety-mediated facilitation of behavioral inhibition: Threat processing and defensive reactivity during a go/no-go task.

Resting state connectivity of the human habenula at ultra-high field.

Intrinsic functional connectivity of the central nucleus of the amygdala and bed nucleus of the stria terminalis.

Threat of shock increases excitability and connectivity of the intraparietal sulcus.