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Department of Pathology,
Erasmus MC Cancer Institute,
Department of Pathology, Erasmus MC Cancer Institute
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Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.
American journal of human genetics May, 2003 | Pubmed ID: 12658575
APC dosage effects in tumorigenesis and stem cell differentiation.
The International journal of developmental biology , 2004 | Pubmed ID: 15349813
Genomic profiling by DNA amplification of laser capture microdissected tissues and array CGH.
Nucleic acids research Oct, 2004 | Pubmed ID: 15514107
Stem cells and metastatic cancer: fatal attraction?
PLoS medicine Dec, 2006 | Pubmed ID: 17194186
Aneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and human.
The American journal of pathology Jan, 2007 | Pubmed ID: 17200209
Wnt/beta-catenin signaling in cancer stemness and malignant behavior.
Current opinion in cell biology Apr, 2007 | Pubmed ID: 17306971
SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice.
The American journal of pathology Aug, 2007 | Pubmed ID: 17569777
Smad4 haploinsufficiency: a matter of dosage.
PathoGenetics , 2008 | Pubmed ID: 19014666
The stem of cancer.
Cancer cell Feb, 2009 | Pubmed ID: 19185843
Progesterone inhibition of Wnt/beta-catenin signaling in normal endometrium and endometrial cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2009 | Pubmed ID: 19737954
Nuclear beta-catenin expression and Wnt signalling: in defence of the dogma.
The Journal of pathology Jul, 2010 | Pubmed ID: 20527017
Wnt/Β-catenin and sex hormone signaling in endometrial homeostasis and cancer.
Oncotarget Nov, 2010 | Pubmed ID: 21317462
Loss of APC function in mesenchymal cells surrounding the Müllerian duct leads to myometrial defects in adult mice.
Molecular and cellular endocrinology Jul, 2011 | Pubmed ID: 21664244
Familial adenomatous polyposis-associated desmoids display significantly more genetic changes than sporadic desmoids.
PloS one , 2011 | Pubmed ID: 21931686
Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion.
Cell stem cell Oct, 2011 | Pubmed ID: 21982234
CCAT2, a novel non-coding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer.
Genome research Jun, 2013 | Pubmed ID: 23796952
Cancer stem cells, pluripotency, and cellular heterogeneity: a WNTer perspective.
Current topics in developmental biology , 2014 | Pubmed ID: 24439813
Expression of HLA class I antigen, aspirin use, and survival after a diagnosis of colon cancer.
JAMA internal medicine May, 2014 | Pubmed ID: 24687028
IL6/JAK1/STAT3 Signaling Blockade in Endometrial Cancer Affects the ALDHhi/CD126+ Stem-like Component and Reduces Tumor Burden.
Cancer research Sep, 2015 | Pubmed ID: 26130650
Secreted Phospholipases A2 Are Intestinal Stem Cell Niche Factors with Distinct Roles in Homeostasis, Inflammation, and Cancer.
Cell stem cell Jul, 2016 | Pubmed ID: 27292189
The role of S100a4 (Mts1) in Apc- and Smad4-driven tumour onset and progression.
European journal of cancer (Oxford, England : 1990) Nov, 2016 | Pubmed ID: 27750112
Interplay between metabolic identities in the intestinal crypt supports stem cell function.
Nature 03, 2017 | Pubmed ID: 28273069
DOC1-Dependent Recruitment of NURD Reveals Antagonism with SWI/SNF during Epithelial-Mesenchymal Transition in Oral Cancer Cells.
Cell reports Jul, 2017 | Pubmed ID: 28683324
Erasmus University Medical Center
Matthias Schewe1,
Andrea Sacchetti1,
Mark Schmitt1,
Riccardo Fodde1
1Department of Pathology, Erasmus MC Cancer Institute, Erasmus University Medical Center
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