Department of Biochemistry and Molecular Biology and Molecular,
Cellular and Integrated Neuroscience Program,
Department of Biochemistry and Molecular Biology and Molecular, Cellular and Integrated Neuroscience Program
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ADF/cofilin.
Current biology : CB Apr, 2008 | Pubmed ID: 18397729
Xenopus actin depolymerizing factor/cofilin (XAC) is responsible for the turnover of actin filaments in Listeria monocytogenes tails.
The Journal of cell biology Mar, 1997 | Pubmed ID: 9087446
Caffeine eliminates gamma-ray-induced G2-phase delay in human tumor cells but not in normal cells.
Radiation research Jan, 2002 | Pubmed ID: 11754638
Xenopus actin-interacting protein 1 (XAip1) enhances cofilin fragmentation of filaments by capping filament ends.
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12055192
Head, neck, and spines: a role for LIMK-1 in the hippocampus.
Neuron Jul, 2002 | Pubmed ID: 12123600
ADF/cofilin and actin dynamics in disease.
Trends in cell biology Dec, 2002 | Pubmed ID: 12495849
Actin-ATP hydrolysis is a major energy drain for neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2003 | Pubmed ID: 12514193
Specification of actin filament function and molecular composition by tropomyosin isoforms.
Molecular biology of the cell Mar, 2003 | Pubmed ID: 12631719
Introduction to cytoskeletal dynamics and pathfinding of neuronal growth cones.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society Apr, 2003 | Pubmed ID: 12642618
Regulation of growth cone actin dynamics by ADF/cofilin.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society Apr, 2003 | Pubmed ID: 12642619
Production and use of replication-deficient adenovirus for transgene expression in neurons.
Methods in cell biology , 2003 | Pubmed ID: 12884701
Regulation of the neuronal actin cytoskeleton by ADF/cofilin.
Journal of neurobiology Jan, 2004 | Pubmed ID: 14598374
A proposed mechanism for cell polarization with no external cues.
Cell motility and the cytoskeleton Jun, 2004 | Pubmed ID: 15083531
In vitro activity differences between proteins of the ADF/cofilin family define two distinct subgroups.
Biochemistry Jun, 2004 | Pubmed ID: 15170350
Cross-reactivity of antibodies to actin- depolymerizing factor/cofilin family proteins and identification of the major epitope recognized by a mammalian actin-depolymerizing factor/cofilin antibody.
Electrophoresis Aug, 2004 | Pubmed ID: 15300782
Regulating filopodial dynamics through actin-depolymerizing factor/cofilin.
Anatomical science international Dec, 2004 | Pubmed ID: 15633455
Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.
The EMBO journal Feb, 2005 | Pubmed ID: 15660133
Gelsolin mediates calcium-dependent disassembly of Listeria actin tails.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2005 | Pubmed ID: 15671163
Regulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets.
Blood Jan, 2006 | Pubmed ID: 16219803
Beta-secretase-cleaved amyloid precursor protein accumulates at actin inclusions induced in neurons by stress or amyloid beta: a feedforward mechanism for Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2005 | Pubmed ID: 16339026
Essential requirement for Rho family GTPase signaling in Pax3 induced mesenchymal-epithelial transition.
Cellular signalling Sep, 2006 | Pubmed ID: 16442263
Formation of actin-ADF/cofilin rods transiently retards decline of mitochondrial potential and ATP in stressed neurons.
American journal of physiology. Cell physiology Nov, 2006 | Pubmed ID: 16738008
Association of gag multimers with filamentous actin during equine infectious anemia virus assembly.
Current HIV research May, 2007 | Pubmed ID: 17504173
Cofilin-mediated neurodegeneration in Alzheimer's disease and other amyloidopathies.
Molecular neurobiology Feb, 2007 | Pubmed ID: 17519504
BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin.
The Journal of cell biology Jul, 2007 | Pubmed ID: 17606869
Actin-binding proteins take the reins in growth cones.
Nature reviews. Neuroscience Feb, 2008 | Pubmed ID: 18209731
Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation.
Developmental cell Nov, 2008 | Pubmed ID: 19000834
Cytoskeletal pathologies of Alzheimer disease.
Cell motility and the cytoskeleton Aug, 2009 | Pubmed ID: 19479823
Regulation of acetylcholine receptor clustering by ADF/cofilin-directed vesicular trafficking.
Nature neuroscience Jul, 2009 | Pubmed ID: 19483689
Growth cone-like waves transport actin and promote axonogenesis and neurite branching.
Developmental neurobiology Oct, 2009 | Pubmed ID: 19513994
Mapping cofilin-actin rods in stressed hippocampal slices and the role of cdc42 in amyloid-beta-induced rods.
Journal of Alzheimer's disease : JAD , 2009 | Pubmed ID: 19542631
Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2009 | Pubmed ID: 19828813
Isolation and characterization of cytoplasmic cofilin-actin rods.
The Journal of biological chemistry Feb, 2010 | Pubmed ID: 20022956
ADF/cofilin: a functional node in cell biology.
Trends in cell biology Apr, 2010 | Pubmed ID: 20133134
Activation of ADF/cofilin mediates attractive growth cone turning toward nerve growth factor and netrin-1.
Developmental neurobiology Jul, 2010 | Pubmed ID: 20506164
Luteinizing hormone receptor-stimulated progesterone production by preovulatory granulosa cells requires protein kinase A-dependent activation/dephosphorylation of the actin dynamizing protein cofilin.
Molecular endocrinology (Baltimore, Md.) Sep, 2010 | Pubmed ID: 20610540
Arp2/3- and cofilin-coordinated actin dynamics is required for insulin-mediated GLUT4 translocation to the surface of muscle cells.
Molecular biology of the cell Oct, 2010 | Pubmed ID: 20739464
ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity.
Nature neuroscience Oct, 2010 | Pubmed ID: 20835250
Roles of ADF/cofilin in actin polymerization and beyond.
F1000 biology reports Aug, 2010 | Pubmed ID: 21173851
Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation.
Molecular neurodegeneration Jan, 2011 | Pubmed ID: 21261978
Amyloid-β-induced amyloid-β secretion: a possible feed-forward mechanism in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD , 2011 | Pubmed ID: 21297255
Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease.
Human molecular genetics May, 2011 | Pubmed ID: 21355047
Rapid changes in phospho-MAP/tau epitopes during neuronal stress: cofilin-actin rods primarily recruit microtubule binding domain epitopes.
PloS one , 2011 | Pubmed ID: 21738590
Neuronal guidance: a redox signal involving Mical.
Current biology : CB Apr, 2010 | Pubmed ID: 21749956
Listeria monocytogenes cell invasion: a new role for cofilin in co-ordinating actin dynamics and membrane lipids.
Molecular microbiology Aug, 2011 | Pubmed ID: 21762221
ADF/cofilin regulates actomyosin assembly through competitive inhibition of myosin II binding to F-actin.
Developmental cell Mar, 2012 | Pubmed ID: 22421043
Incorporation of cofilin into rods depends on disulfide intermolecular bonds: implications for actin regulation and neurodegenerative disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2012 | Pubmed ID: 22573689
Instantaneous inactivation of cofilin reveals its function of F-actin disassembly in lamellipodia.
Molecular biology of the cell Jul, 2013 | Pubmed ID: 23676663
Non-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cells.
BMC cell biology Oct, 2013 | Pubmed ID: 24093776
A genetically encoded reporter for real-time imaging of cofilin-actin rods in living neurons.
PloS one , 2013 | Pubmed ID: 24391794
Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons.
PloS one , 2014 | Pubmed ID: 24760020
Cellular prion protein: A co-receptor mediating neuronal cofilin-actin rod formation induced by β-amyloid and proinflammatory cytokines.
Prion , 2014 | Pubmed ID: 25426519
Cofilin-2 phosphorylation and sequestration in myocardial aggregates: novel pathogenetic mechanisms for idiopathic dilated cardiomyopathy.
Journal of the American College of Cardiology Mar, 2015 | Pubmed ID: 25814227
Actin dynamics and cofilin-actin rods in alzheimer disease.
Cytoskeleton (Hoboken, N.J.) Sep, 2016 | Pubmed ID: 26873625
Cofilin Regulates Nuclear Architecture through a Myosin-II Dependent Mechanotransduction Module.
Scientific reports Jan, 2017 | Pubmed ID: 28102353
Peptide regulation of cofilin activity in the CNS: A novel therapeutic approach for treatment of multiple neurological disorders.
Pharmacology & therapeutics Jul, 2017 | Pubmed ID: 28232023
Cephalostatin 1 analogues activate apoptosis via the endoplasmic reticulum stress signaling pathway.
European journal of pharmacology Nov, 2017 | Pubmed ID: 29154934
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