James R. Bamburg

ADF/cofilin.

Xenopus actin depolymerizing factor/cofilin (XAC) is responsible for the turnover of actin filaments in Listeria monocytogenes tails.

Caffeine eliminates gamma-ray-induced G2-phase delay in human tumor cells but not in normal cells.

Xenopus actin-interacting protein 1 (XAip1) enhances cofilin fragmentation of filaments by capping filament ends.

Head, neck, and spines: a role for LIMK-1 in the hippocampus.

ADF/cofilin and actin dynamics in disease.

Actin-ATP hydrolysis is a major energy drain for neurons.

Specification of actin filament function and molecular composition by tropomyosin isoforms.

Introduction to cytoskeletal dynamics and pathfinding of neuronal growth cones.

Regulation of growth cone actin dynamics by ADF/cofilin.

Production and use of replication-deficient adenovirus for transgene expression in neurons.

Regulation of the neuronal actin cytoskeleton by ADF/cofilin.

A proposed mechanism for cell polarization with no external cues.

In vitro activity differences between proteins of the ADF/cofilin family define two distinct subgroups.

Cross-reactivity of antibodies to actin- depolymerizing factor/cofilin family proteins and identification of the major epitope recognized by a mammalian actin-depolymerizing factor/cofilin antibody.

Regulating filopodial dynamics through actin-depolymerizing factor/cofilin.

Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.

Gelsolin mediates calcium-dependent disassembly of Listeria actin tails.

Regulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets.

Beta-secretase-cleaved amyloid precursor protein accumulates at actin inclusions induced in neurons by stress or amyloid beta: a feedforward mechanism for Alzheimer's disease.

Essential requirement for Rho family GTPase signaling in Pax3 induced mesenchymal-epithelial transition.

Formation of actin-ADF/cofilin rods transiently retards decline of mitochondrial potential and ATP in stressed neurons.

Association of gag multimers with filamentous actin during equine infectious anemia virus assembly.

Cofilin-mediated neurodegeneration in Alzheimer's disease and other amyloidopathies.

BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin.

Actin-binding proteins take the reins in growth cones.

Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation.

Cytoskeletal pathologies of Alzheimer disease.

Regulation of acetylcholine receptor clustering by ADF/cofilin-directed vesicular trafficking.

Growth cone-like waves transport actin and promote axonogenesis and neurite branching.

Mapping cofilin-actin rods in stressed hippocampal slices and the role of cdc42 in amyloid-beta-induced rods.

Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations.

Isolation and characterization of cytoplasmic cofilin-actin rods.

ADF/cofilin: a functional node in cell biology.

Activation of ADF/cofilin mediates attractive growth cone turning toward nerve growth factor and netrin-1.

Luteinizing hormone receptor-stimulated progesterone production by preovulatory granulosa cells requires protein kinase A-dependent activation/dephosphorylation of the actin dynamizing protein cofilin.

Arp2/3- and cofilin-coordinated actin dynamics is required for insulin-mediated GLUT4 translocation to the surface of muscle cells.

ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity.

Roles of ADF/cofilin in actin polymerization and beyond.

Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation.

Amyloid-β-induced amyloid-β secretion: a possible feed-forward mechanism in Alzheimer's Disease.

Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease.

Rapid changes in phospho-MAP/tau epitopes during neuronal stress: cofilin-actin rods primarily recruit microtubule binding domain epitopes.

Neuronal guidance: a redox signal involving Mical.

Listeria monocytogenes cell invasion: a new role for cofilin in co-ordinating actin dynamics and membrane lipids.

ADF/cofilin regulates actomyosin assembly through competitive inhibition of myosin II binding to F-actin.

Incorporation of cofilin into rods depends on disulfide intermolecular bonds: implications for actin regulation and neurodegenerative disease.

Instantaneous inactivation of cofilin reveals its function of F-actin disassembly in lamellipodia.

Non-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cells.

A genetically encoded reporter for real-time imaging of cofilin-actin rods in living neurons.

Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons.

Cellular prion protein: A co-receptor mediating neuronal cofilin-actin rod formation induced by β-amyloid and proinflammatory cytokines.

Cofilin-2 phosphorylation and sequestration in myocardial aggregates: novel pathogenetic mechanisms for idiopathic dilated cardiomyopathy.

Actin dynamics and cofilin-actin rods in alzheimer disease.

Cofilin Regulates Nuclear Architecture through a Myosin-II Dependent Mechanotransduction Module.

Peptide regulation of cofilin activity in the CNS: A novel therapeutic approach for treatment of multiple neurological disorders.

Cephalostatin 1 analogues activate apoptosis via the endoplasmic reticulum stress signaling pathway.