Lisa Bouchier-Hayes

A unified model of mammalian BCL-2 protein family interactions at the mitochondria.

PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling.

Armed oncolytic virus enhances immune functions of chimeric antigen receptor-modified T cells in solid tumors.

Bortezomib sensitizes non-small cell lung cancer to mesenchymal stromal cell-delivered inducible caspase-9-mediated cytotoxicity.

Measuring initiator caspase activation by bimolecular fluorescence complementation.

Measuring caspase activity by Förster resonance energy transfer.

Imaging-based methods for assessing caspase activity in single cells.

Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death.

Mesenchymal Stromal Cells for Linked Delivery of Oncolytic and Apoptotic Adenoviruses to Non-small-cell Lung Cancers.

Induction of cell death by the novel proteasome inhibitor marizomib in glioblastoma in vitro and in vivo.

Detection of Initiator Caspase Induced Proximity in Single Cells by Caspase Bimolecular Fluorescence Complementation.

NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus.

The nucleolus: A new home for the PIDDosome.

Direct pro-apoptotic role for NPM1 as a regulator of PIDDosome formation.

Inflammatory caspase regulation: maintaining balance between inflammation and cell death in health and disease.

Targeting apoptotic caspases in cancer.

Caspase-2 Substrates: To Apoptosis, Cell Cycle Control, and Beyond.

Noncanonical Roles of Caspase-4 and Caspase-5 in Heme-Driven IL-1β Release and Cell Death.

Caspase-2 regulates S-phase cell cycle events to protect from DNA damage accumulation independent of apoptosis.

Cellular autophagy, an unbidden effect of caspase inhibition by zVAD-fmk.