Chang Won is an Assistant Professor of Department of Medicine and Division of Cardiology at the Icahn School of Medicine at Mount Sinai, New York since 2015. In the last decade, his research has been focused on identifying and characterizing novel molecular pathways in heart failure. One area of particular interest to him is the role of post-translational modification of key proteins involved in cardiac dysfunction. He designed a multi-faceted approach to profile proteins in cardiomyocytes that interact with sarcoplasmic reticulum calcium ATPase (SERCA2a) pump. His efforts have led to the identification of Small Ubiquitin-like Modifier type 1 (SUMO1) as a potentially important target for heart failure therapy.
