Henri Xhaard

Impact of probe compound in MRP2 vesicular transport assays.

Study of interaction between PEG carrier and three relevant drug molecules: piroxicam, paclitaxel, and hematoporphyrin.

Systematic structure-activity study on potential chaperone lead compounds for acid α-glucosidase.

Applying linear and non-linear methods for parallel prediction of volume of distribution and fraction of unbound drug.

SVM classification and CoMSIA modeling of UGT1A6 interacting molecules.

OX1 and OX2 orexin/hypocretin receptor pharmacogenetics.

Nostosins, Trypsin Inhibitors Isolated from the Terrestrial Cyanobacterium Nostoc sp. Strain FSN.

Integrated in vitro-in silico screening strategy for the discovery of antibacterial compounds.

Exploring the structure-activity relationships of ABCC2 modulators using a screening approach.

Modeling of the OX1R-orexin-A complex suggests two alternative binding modes.

IDAAPM: integrated database of ADMET and adverse effects of predictive modeling based on FDA approved drug data.

Pharmacophore Model To Discover OX1 and OX2 Orexin Receptor Ligands.

Predictive Modeling of Ocular Pharmacokinetics and Adverse Effects.

A structure-activity relationship study of ABCC2 inhibitors.

Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity.

Stapled truncated orexin peptides as orexin receptor agonists.

Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors.

Azulene-based compounds for targeting orexin receptors.

Predictive classification models and targets identification for betulin derivatives as Leishmania donovani inhibitors.

Pharmacological characterization of the orexin/hypocretin receptor agonist Nag 26.

Determinants of Orexin Receptor Binding and Activation-A Molecular Dynamics Study.

Structure-Activity Relationships of 1-Benzoylazulenes at the OX and OX Orexin Receptors.

Cartography of rhodopsin-like G protein-coupled receptors across vertebrate genomes.

Asymmetry in catalysis by membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor.

Characterization of Ionizable Groups' Environments in Proteins and Protein-Ligand Complexes through a Statistical Analysis of the Protein Data Bank.

Modeling membrane proteins: The importance of cysteine amino-acids.