Drug Research Program,
Division of Pharmaceutical Chemistry and Technology,
Faculty of Pharmacy,
Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy
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Impact of probe compound in MRP2 vesicular transport assays.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences May, 2012 | Pubmed ID: 22406294
Study of interaction between PEG carrier and three relevant drug molecules: piroxicam, paclitaxel, and hematoporphyrin.
The journal of physical chemistry. B Jun, 2012 | Pubmed ID: 22587534
Systematic structure-activity study on potential chaperone lead compounds for acid α-glucosidase.
ChemMedChem Nov, 2012 | Pubmed ID: 22969039
Applying linear and non-linear methods for parallel prediction of volume of distribution and fraction of unbound drug.
PloS one , 2013 | Pubmed ID: 24116008
SVM classification and CoMSIA modeling of UGT1A6 interacting molecules.
Journal of chemical information and modeling Apr, 2014 | Pubmed ID: 24588678
OX1 and OX2 orexin/hypocretin receptor pharmacogenetics.
Frontiers in neuroscience , 2014 | Pubmed ID: 24834023
Nostosins, Trypsin Inhibitors Isolated from the Terrestrial Cyanobacterium Nostoc sp. Strain FSN.
Journal of natural products Aug, 2014 | Pubmed ID: 25069058
Integrated in vitro-in silico screening strategy for the discovery of antibacterial compounds.
Assay and drug development technologies Jan-Feb, 2015 | Pubmed ID: 25710544
Exploring the structure-activity relationships of ABCC2 modulators using a screening approach.
Bioorganic & medicinal chemistry Jul, 2015 | Pubmed ID: 25935289
Modeling of the OX1R-orexin-A complex suggests two alternative binding modes.
BMC structural biology May, 2015 | Pubmed ID: 25957175
IDAAPM: integrated database of ADMET and adverse effects of predictive modeling based on FDA approved drug data.
Journal of cheminformatics , 2016 | Pubmed ID: 27303447
Pharmacophore Model To Discover OX1 and OX2 Orexin Receptor Ligands.
Journal of medicinal chemistry Sep, 2016 | Pubmed ID: 27546834
Predictive Modeling of Ocular Pharmacokinetics and Adverse Effects.
Current pharmaceutical design , 2016 | Pubmed ID: 27669964
A structure-activity relationship study of ABCC2 inhibitors.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences May, 2017 | Pubmed ID: 28185990
Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity.
PloS one , 2017 | Pubmed ID: 28575023
Stapled truncated orexin peptides as orexin receptor agonists.
Peptides 04, 2018 | Pubmed ID: 29475074
Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors.
European journal of medicinal chemistry May, 2018 | Pubmed ID: 29649744
Azulene-based compounds for targeting orexin receptors.
European journal of medicinal chemistry Sep, 2018 | Pubmed ID: 30077889
Predictive classification models and targets identification for betulin derivatives as Leishmania donovani inhibitors.
Journal of cheminformatics Aug, 2018 | Pubmed ID: 30120601
Pharmacological characterization of the orexin/hypocretin receptor agonist Nag 26.
European journal of pharmacology Oct, 2018 | Pubmed ID: 30194937
Determinants of Orexin Receptor Binding and Activation-A Molecular Dynamics Study.
The journal of physical chemistry. B Mar, 2019 | Pubmed ID: 30786708
Structure-Activity Relationships of 1-Benzoylazulenes at the OX and OX Orexin Receptors.
ChemMedChem May, 2019 | Pubmed ID: 30892823
Cartography of rhodopsin-like G protein-coupled receptors across vertebrate genomes.
Scientific reports May, 2019 | Pubmed ID: 31064998
Asymmetry in catalysis by membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor.
Science advances May, 2019 | Pubmed ID: 31131322
Characterization of Ionizable Groups' Environments in Proteins and Protein-Ligand Complexes through a Statistical Analysis of the Protein Data Bank.
ACS omega Oct, 2017 | Pubmed ID: 31457307
Modeling membrane proteins: The importance of cysteine amino-acids.
Journal of structural biology Oct, 2019 | Pubmed ID: 31593760
Keni Vidilaseris*,1,
Niklas G. Johansson*,2,
Ainoleena Turku2,
Alexandros Kiriazis2,
Gustav Boije af Gennäs2,
Jari Yli-Kauhaluoma2,
Henri Xhaard2,
Adrian Goldman1,3
1Research Program in Molecular and Integrative Biosciences, University of Helsinki,
2Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki,
3School of Biomedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds
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