Yifan Dai

Disabling of nephrogenesis in porcine embryos via CRISPR/Cas9-mediated SIX1 and SIX4 gene targeting.

Cellular production of n-3 PUFAs and reduction of n-6-to-n-3 ratios in the pancreatic beta-cells and islets enhance insulin secretion and confer protection against cytokine-induced cell death.

Human dominant-negative class II transactivator transgenic pigs - effect on the human anti-pig T-cell immune response and immune status.

The potential of genetically-engineered pigs in providing an alternative source of organs and cells for transplantation.

Transgenic overproduction of omega-3 polyunsaturated fatty acids provides neuroprotection and enhances endogenous neurogenesis after stroke.

Unbalanced omega-6/omega-3 ratio in red meat products in China.

Inhibition of endometrial cancer by n-3 polyunsaturated fatty acids in preclinical models.

Genome-wide screen for serum microRNA expression profile in mfat-1 transgenic mice.

Endogenous ω-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice.

The potential of the combination of CRISPR/Cas9 and pluripotent stem cells to provide human organs from chimaeric pigs.

[Preparation of monoclonal antibody against bovine phosphoenolpyruvate carboxykinase].

Potential alternative approaches to xenotransplantation.

Generation of B cell-deficient pigs by highly efficient CRISPR/Cas9-mediated gene targeting.

Generation of monoclonal antibodies against n-3 fatty acid desaturase.

Endothelin-1-induced mini-stroke in the dorsal hippocampus or lateral amygdala results in deficits in learning and memory.

Dominant-negative inhibition of glucose-dependent insulinotropic polypeptide impairs function of β cells in transgenic pigs.

Highly conserved epigenetic regulation of BOULE and DAZL is associated with human fertility.

Circulating Organ-Specific MicroRNAs Serve as Biomarkers in Organ-Specific Diseases: Implications for Organ Allo- and Xeno-Transplantation.

Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning.

Elevation of n-3/n-6 PUFAs ratio suppresses mTORC1 and prevents colorectal carcinogenesis associated with APC mutation.

Initial study of α1,3-galactosyltransferase gene-knockout/CD46 pig full-thickness corneal xenografts in rhesus monkeys.

Klotho attenuated antibody-mediated porcine endothelial cell activation and injury.

Pig-to-Primate Islet Xenotransplantation: Past, Present, and Future.

Enhancement of porcine intramuscular fat content by overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase in skeletal muscle.

ω-3 polyunsaturated fatty acids ameliorate type 1 diabetes and autoimmunity.

Omega-3 Polyunsaturated Fatty Acids Attenuate Fibroblast Activation and Kidney Fibrosis Involving MTORC2 Signaling Suppression.

Altered expression of eNOS, prostacyclin synthase, prostaglandin G/H synthase, and thromboxane synthase in porcine aortic endothelial cells after exposure to human serum-relevance to xenotransplantation.

mfat-1 transgene protects cultured adult neural stem cells against cobalt chloride-mediated hypoxic injury by activating Nrf2/ARE pathways.

Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting.

DNA demethylation pattern of in-vitro fertilized and cloned porcine pronuclear stage embryos.

Potential Antigens Involved in Delayed Xenograft Rejection in a Ggta1/Cmah Dko Pig-to-Monkey Model.

Identification of novel diagnostic biomarkers for thyroid carcinoma.

Ptrf transgenic mice exhibit obesity and fatty liver.

The Sda and Cad glycan antigens and their glycosyltransferase, β1,4GalNAcT-II, in xenotransplantation.

Overexpressing dominant-negative FGFR2-IIIb impedes lung branching morphogenesis in pigs.

Reducing immunoreactivity of porcine bioprosthetic heart valves by genetically-deleting three major glycan antigens, GGTA1/β4GalNT2/CMAH.

Spermine Alleviates Acute Liver Injury by Inhibiting Liver-Resident Macrophage Pro-Inflammatory Response Through ATG5-Dependent Autophagy.

Transplant Tolerance: Current Insights and Strategies for Long-Term Survival of Xenografts.

Antigenicity of tissues and organs from GGTA1/CMAH/β4GalNT2 triple gene knockout pigs.

Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs.

Whole transcriptome sequencing analyses of DHA treated glioblastoma cells.

Circulating pig-specific DNA as a novel biomarker for monitoring xenograft rejection.

Derivation of novel naive-like porcine embryonic stem cells by a reprogramming factor-assisted strategy.

Downregulation of Gabarapl1 significantly attenuates antibody binding to porcine aortic endothelial cells.

OSBPL2-disrupted pigs recapitulate dual features of human hearing loss and hypercholesterolaemia.

Induction of diabetes in cynomolgus monkey with one shot of analytical grade streptozotocin.