Sander Granneman

Building ribosomes: even more expensive than expected?

Identification of protein binding sites on U3 snoRNA and pre-rRNA by UV cross-linking and high-throughput analysis of cDNAs.

Prp43 bound at different sites on the pre-rRNA performs distinct functions in ribosome synthesis.

Cracking pre-40S ribosomal subunit structure by systematic analyses of RNA-protein cross-linking.

The nuclear RNA polymerase II surveillance system targets polymerase III transcripts.

Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing.

Cross-linking, ligation, and sequencing of hybrids reveals RNA-RNA interactions in yeast.

A cluster of ribosome synthesis factors regulate pre-rRNA folding and 5.8S rRNA maturation by the Rat1 exonuclease.

Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits.

Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel.

Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome.

Spliceosome-mediated decay (SMD) regulates expression of nonintronic genes in budding yeast.

Rrp5 binding at multiple sites coordinates pre-rRNA processing and assembly.

Coupled GTPase and remodelling ATPase activities form a checkpoint for ribosome export.

PAR-CLIP data indicate that Nrd1-Nab3-dependent transcription termination regulates expression of hundreds of protein coding genes in yeast.

Identification of bacteriophage-encoded anti-sRNAs in pathogenic Escherichia coli.

Snapshots of pre-rRNA structural flexibility reveal eukaryotic 40S assembly dynamics at nucleotide resolution.

Rio1 mediates ATP-dependent final maturation of 40S ribosomal subunits.

A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation.

The DEAH-box helicase Dhr1 dissociates U3 from the pre-rRNA to promote formation of the central pseudoknot.

A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation.

Cell populations can use aneuploidy to survive telomerase insufficiency.

Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling.

Loss of the Yeast SR Protein Npl3 Alters Gene Expression Due to Transcription Readthrough.

The Nrd1-like protein Seb1 coordinates cotranscriptional 3' end processing and polyadenylation site selection.

Robust statistical modeling improves sensitivity of high-throughput RNA structure probing experiments.

Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress.

Specialized box C/D snoRNPs act as antisense guides to target RNA base acetylation.

High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination.

Maturation of the 90S pre-ribosome requires Mrd1 dependent U3 snoRNA and 35S pre-rRNA structural rearrangements.

An RNA-dependent mechanism for transient expression of bacterial translocation filaments.

High-Resolution, High-Throughput Analysis of Hfq-Binding Sites Using UV Crosslinking and Analysis of cDNA (CRAC).

Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.

Probing the RNA-Binding Proteome from Yeast to Man: Major Advances and Challenges.

Hfq CLASH uncovers sRNA-target interaction networks linked to nutrient availability adaptation.