Institute for Chemistry and Biochemistry
Petra Knaus has not added Biography.
If you are Petra Knaus and would like to personalize this page please email our Author Liaison for assistance.
Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2.
The Journal of clinical investigation Sep, 2005 | Pubmed ID: 16127465
Monomeric and dimeric GDF-5 show equal type I receptor binding and oligomerization capability and have the same biological activity.
Biological chemistry Apr, 2006 | Pubmed ID: 16606344
Recent advances in BMP receptor signaling.
Cytokine & growth factor reviews Oct-Dec, 2009 | Pubmed ID: 19897402
Quantitative analysis of TGFBR2 mutations in Marfan-syndrome-related disorders suggests a correlation between phenotypic severity and Smad signaling activity.
Journal of cell science Dec, 2010 | Pubmed ID: 21098638
Noggin.
The international journal of biochemistry & cell biology Apr, 2011 | Pubmed ID: 21256973
MicroRNAs differentially expressed in postnatal aortic development downregulate elastin via 3' UTR and coding-sequence binding sites.
PloS one Jan, 2011 | Pubmed ID: 21305018
Comprehensive analysis of TGF-β and BMP receptor interactomes.
European journal of cell biology Apr, 2012 | Pubmed ID: 21715044
A portrait of Transforming Growth Factor β superfamily signalling: Background matters.
The international journal of biochemistry & cell biology Mar, 2012 | Pubmed ID: 22226817
BMPs are mediators in tissue crosstalk of the regenerating musculoskeletal system.
Cell and tissue research Mar, 2012 | Pubmed ID: 22327483
SMAD versus non-SMAD signaling is determined by lateral mobility of bone morphogenetic protein (BMP) receptors.
The Journal of biological chemistry Nov, 2012 | Pubmed ID: 22961979
Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva.
The Journal of biological chemistry Oct, 2012 | Pubmed ID: 22977237
Constitutively active ALK2 receptor mutants require type II receptor cooperation.
Molecular and cellular biology Jun, 2013 | Pubmed ID: 23572558
Growth and differentiation factor 3 induces expression of genes related to differentiation in a model of cancer stem cells and protects them from retinoic acid-induced apoptosis.
PloS one , 2013 | Pubmed ID: 23950971
BMP10 as a potent inducer of trophoblast differentiation in human embryonic and induced pluripotent stem cells.
Biomaterials Dec, 2013 | Pubmed ID: 24070570
Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation.
The Journal of biological chemistry Feb, 2015 | Pubmed ID: 25368322
Bone morphogenetic protein signaling in bone homeostasis.
Bone Nov, 2015 | Pubmed ID: 26051467
VE-cadherin facilitates BMP-induced endothelial cell permeability and signaling.
Journal of cell science Jan, 2016 | Pubmed ID: 26598555
Actions from head to toe: An update on Bone/Body Morphogenetic Proteins in health and disease.
Cytokine & growth factor reviews Feb, 2016 | Pubmed ID: 26803465
Emerging regulators of BMP bioavailability.
Bone Dec, 2016 | Pubmed ID: 26825814
YAP-Mediated Mechanotransduction in Skeletal Muscle.
Frontiers in physiology , 2016 | Pubmed ID: 26909043
Dynamin-dependent endocytosis of Bone Morphogenetic Protein2 (BMP2) and its receptors is dispensable for the initiation of Smad signaling.
The international journal of biochemistry & cell biology 07, 2016 | Pubmed ID: 27113717
The Role of Titanium Surface Nanostructuring on Preosteoblast Morphology, Adhesion, and Migration.
Advanced healthcare materials Aug, 2017 | Pubmed ID: 28371540
Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk tip cell competence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 11, 2017 | Pubmed ID: 28733457
IRS4, a novel modulator of BMP/Smad and Akt signalling during early muscle differentiation.
Scientific reports 08, 2017 | Pubmed ID: 28821740
Correction for Bagarova et al., "Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation".
Molecular and cellular biology 10, 2017 | Pubmed ID: 28899999
Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels.
Molecular systems biology 01, 2018 | Pubmed ID: 29371237
Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica.
PLoS genetics 03, 2018 | Pubmed ID: 29561836
Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation.
Human molecular genetics 09, 2018 | Pubmed ID: 29878125
Load-induced osteogenic differentiation of mesenchymal stromal cells is caused by mechano-regulated autocrine signaling.
Journal of tissue engineering and regenerative medicine 11, 2019 | Pubmed ID: 31359634
Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling.
Cells 10, 2019 | Pubmed ID: 31635347
Lessons from LIMK1 enzymology and their impact on inhibitor design.
The Biochemical journal 11, 2019 | Pubmed ID: 31652302
Sex-specific metabolic and functional differences in human umbilical vein endothelial cells from twin pairs.
Atherosclerosis 12, 2019 | Pubmed ID: 31706078
AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells.
Molecular biology of the cell 01, 2020 | Pubmed ID: 31800378
BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics.
PLoS biology 12, 2019 | Pubmed ID: 31826007
Biomechanical stress provides a second hit in the establishment of BMP/TGFβ-related vascular disorders.
Cell stress Jan, 2020 | Pubmed ID: 32043077
BMP signalling in a mechanical context - Implications for bone biology.
Bone 08, 2020 | Pubmed ID: 32422297
Enhanced Biological Activity of BMP-2 Bound to Surface-Grafted Heparan Sulfate.
Advanced biosystems Apr, 2017 | Pubmed ID: 32646162
Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis.
Cell reports 07, 2020 | Pubmed ID: 32668254
ActivinA Induced SMAD1/5 Signaling in an iPSC Derived EC Model of Fibrodysplasia Ossificans Progressiva (FOP) Can Be Rescued by the Drug Candidate Saracatinib.
Stem cell reviews and reports Jun, 2021 | Pubmed ID: 33410098
Optimized expression and purification of a soluble BMP2 variant based on in-silico design.
Protein expression and purification Oct, 2021 | Pubmed ID: 34044133
ACERCA DE JoVE
Copyright © 2024 MyJoVE Corporation. Todos los derechos reservados