Petra Knaus

Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2.

Monomeric and dimeric GDF-5 show equal type I receptor binding and oligomerization capability and have the same biological activity.

Recent advances in BMP receptor signaling.

Quantitative analysis of TGFBR2 mutations in Marfan-syndrome-related disorders suggests a correlation between phenotypic severity and Smad signaling activity.

Noggin.

MicroRNAs differentially expressed in postnatal aortic development downregulate elastin via 3' UTR and coding-sequence binding sites.

Comprehensive analysis of TGF-β and BMP receptor interactomes.

A portrait of Transforming Growth Factor β superfamily signalling: Background matters.

BMPs are mediators in tissue crosstalk of the regenerating musculoskeletal system.

SMAD versus non-SMAD signaling is determined by lateral mobility of bone morphogenetic protein (BMP) receptors.

Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva.

Constitutively active ALK2 receptor mutants require type II receptor cooperation.

Growth and differentiation factor 3 induces expression of genes related to differentiation in a model of cancer stem cells and protects them from retinoic acid-induced apoptosis.

BMP10 as a potent inducer of trophoblast differentiation in human embryonic and induced pluripotent stem cells.

Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation.

Bone morphogenetic protein signaling in bone homeostasis.

VE-cadherin facilitates BMP-induced endothelial cell permeability and signaling.

Actions from head to toe: An update on Bone/Body Morphogenetic Proteins in health and disease.

Emerging regulators of BMP bioavailability.

YAP-Mediated Mechanotransduction in Skeletal Muscle.

Dynamin-dependent endocytosis of Bone Morphogenetic Protein2 (BMP2) and its receptors is dispensable for the initiation of Smad signaling.

The Role of Titanium Surface Nanostructuring on Preosteoblast Morphology, Adhesion, and Migration.

Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk tip cell competence.

IRS4, a novel modulator of BMP/Smad and Akt signalling during early muscle differentiation.

Correction for Bagarova et al., "Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation".

Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels.

Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica.

Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation.

Load-induced osteogenic differentiation of mesenchymal stromal cells is caused by mechano-regulated autocrine signaling.

Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling.

Lessons from LIMK1 enzymology and their impact on inhibitor design.

Sex-specific metabolic and functional differences in human umbilical vein endothelial cells from twin pairs.

AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells.

BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics.

Biomechanical stress provides a second hit in the establishment of BMP/TGFβ-related vascular disorders.

BMP signalling in a mechanical context - Implications for bone biology.

Enhanced Biological Activity of BMP-2 Bound to Surface-Grafted Heparan Sulfate.

Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis.

ActivinA Induced SMAD1/5 Signaling in an iPSC Derived EC Model of Fibrodysplasia Ossificans Progressiva (FOP) Can Be Rescued by the Drug Candidate Saracatinib.

Optimized expression and purification of a soluble BMP2 variant based on in-silico design.