Fiona Oakley

NF-kappaB is a critical regulator of the survival of rodent and human hepatic myofibroblasts.

Nuclear factor-kappaB1: regulation and function.

Angiotensin II activates I kappaB kinase phosphorylation of RelA at Ser 536 to promote myofibroblast survival and liver fibrosis.

MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis.

The c-Rel subunit of nuclear factor-kappaB regulates murine liver inflammation, wound-healing, and hepatocyte proliferation.

The NF-kappaB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes.

BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis.

Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.

The NF-κB subunit c-Rel stimulates cardiac hypertrophy and fibrosis.

Roles of c-Rel signalling in inflammation and disease.

Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation.

Mechanisms and biomarkers of apoptosis in liver disease and fibrosis.

Multigenerational epigenetic adaptation of the hepatic wound-healing response.

Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response.

Serotonin paracrine signaling in tissue fibrosis.

Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor-induced TIMP-1 gene transcription in hepatic stellate cells in mice.

The c-Rel subunit of NF-κB regulates epidermal homeostasis and promotes skin fibrosis in mice.

Utility of B-13 progenitor-derived hepatocytes in hepatotoxicity and genotoxicity studies.

Noninvasive in vivo magnetic resonance measures of glutathione synthesis in human and rat liver as an oxidative stress biomarker.

A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse.

Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3.

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.

Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease.

Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation.

Histone Demethylation and Toll-like Receptor 8-Dependent Cross-Talk in Monocytes Promotes Transdifferentiation of Fibroblasts in Systemic Sclerosis Via Fra-2.

Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease.

Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum.

TPL2 Kinase Is a Crucial Signaling Factor and Mediator of NKT Effector Cytokine Expression in Immune-Mediated Liver Injury.

A new fluorescence-based optical imaging method to non-invasively monitor hepatic myofibroblasts in vivo.

A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A.

The NF-κB1 is a key regulator of acute but not chronic renal injury.

Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage.

The new-generation pan-peroxisome proliferator-activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis.

Identification of a novel TIF-IA-NF-κB nucleolar stress response pathway.

Rapamycin improves healthspan but not inflammaging in nfκb1 mice.

Phosphatidylglycerols are induced by gut dysbiosis and inflammation, and favorably modulate adipose tissue remodeling in obesity.

Enhanced in vivo Optical Imaging of the Inflammatory Response to Acute Liver Injury in C57BL/6 Mice Using a Highly Bright Near-Infrared BODIPY Dye.

A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision-Cut Liver Slices.

Sinusoidal and pericellular fibrosis in adult post-transplant liver biopsies: association with hepatic stellate cell activation and patient outcome.

Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells.

Ammonia Scavenging Prevents Progression of Fibrosis in Experimental Nonalcoholic Fatty Liver Disease.

Editorial overview: Fibrosis.

Implementation of pre-clinical methodologies to study fibrosis and test anti-fibrotic therapy.

Loss of ELK1 has differential effects on age-dependent organ fibrosis.

FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis.

Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis.

Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma.

Long noncoding RNA H19X is a key mediator of TGF-β-driven fibrosis.

Renal injury and hepatic effects from the methylimidazolium ionic liquid M8OI in mouse.

Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis.

cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis.

TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms.

Anti-inflammatory treatment rescues memory deficits during aging in nfkb1 mice.

Age-associated mitochondrial DNA mutations cause metabolic remodelling that contributes to accelerated intestinal tumorigenesis.

c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis.

RNA sequencing reveals changes in the microRNAome of transdifferentiating hepatic stellate cells that are conserved between human and rat.

Author Correction: c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis.

Non-invasive synchronous monitoring of neutrophil migration using whole body near-infrared fluorescence-based imaging.

Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression.

Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner.

A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis.

Key features of the environment promoting liver cancer in the absence of cirrhosis.