Chengjin Ye

Development of Reverse Genetics for the Prototype New World Mammarenavirus Tacaribe Virus.

Reverse genetics approaches for the development of mammarenavirus live-attenuated vaccines.

Rescue of SARS-CoV-2 from a Single Bacterial Artificial Chromosome.

Generation of Recombinant SARS-CoV-2 Using a Bacterial Artificial Chromosome.

Rapid in vitro assays for screening neutralizing antibodies and antivirals against SARS-CoV-2.

Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice.

Generation and Characterization of recombinant SARS-CoV-2 expressing reporter genes.

Selection, identification, and characterization of SARS-CoV-2 monoclonal antibody resistant mutants.

The E484K mutation in the SARS-CoV-2 spike protein reduces but does not abolish neutralizing activity of human convalescent and post-vaccination sera.

Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters.

A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike.

SARS-CoV-2 spike E484K mutation reduces antibody neutralisation.

Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice.

A SARS-CoV-2 nucleocapsid protein TR-FRET assay amenable to high-throughput screening.

Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses.