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Biju B. Thomas

Roski Eye Institute,
Department of Ophthalmology,
Keck School of Medicine,
USC Ginsburg Institute for Biomedical Therapeutics,
USC Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics,
Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine

University of Southern California

BIOGRAPHY

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PUBLICATIONS

Superior colliculus responses to light - preserved by transplantation in a slow degeneration rat model.

Experimental eye research Jul, 2004 | Pubmed ID: 15183098

Optokinetic test to evaluate visual acuity of each eye independently.

Journal of neuroscience methods Sep, 2004 | Pubmed ID: 15325106

Light response differences in the superior colliculus of albino and pigmented rats.

Neuroscience letters Sep, 2005 | Pubmed ID: 15950381

Retinal transplants evaluated by optical coherence tomography in photoreceptor degenerate rats.

Journal of neuroscience methods Mar, 2006 | Pubmed ID: 16129495

Visual functional effects of constant blue light in a retinal degenerate rat model.

Photochemistry and photobiology May-Jun, 2007 | Pubmed ID: 17115798

Retinal transplantation. A treatment strategy for retinal degenerative diseases.

Advances in experimental medicine and biology , 2006 | Pubmed ID: 17249598

Behavioral evaluation of visual function of rats using a visual discrimination apparatus.

Journal of neuroscience methods May, 2007 | Pubmed ID: 17289151

Revisiting nestin expression in retinal progenitor cells in vitro and after transplantation in vivo.

Experimental eye research Jun, 2007 | Pubmed ID: 17451684

Modulatory influence of stimulus parameters on optokinetic head-tracking response.

Neuroscience letters Jul, 2010 | Pubmed ID: 20488227

Successful amelioration of mitochondrial optic neuropathy using the yeast NDI1 gene in a rat animal model.

PloS one Jul, 2010 | Pubmed ID: 20628600

A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer.

Ophthalmic research , 2012 | Pubmed ID: 22868580

Long-term evaluation of Leber's hereditary optic neuropathy-like symptoms in rotenone administered rats.

Neuroscience letters Jan, 2015 | Pubmed ID: 25481764

Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats.

Investigative ophthalmology & visual science 05, 2016 | Pubmed ID: 27233037

Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Aug, 2016 | Pubmed ID: 27335025

Vision Recovery and Connectivity by Fetal Retinal Sheet Transplantation in an Immunodeficient Retinal Degenerate Rat Model.

Investigative ophthalmology & visual science 01, 2017 | Pubmed ID: 28129425

Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models.

Stem cells international , 2017 | Pubmed ID: 28928775

A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.

Science translational medicine 04, 2018 | Pubmed ID: 29618560

Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats.

Investigative ophthalmology & visual science 05, 2018 | Pubmed ID: 29847666

A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Nov, 2018 | Pubmed ID: 30215097

Transcranial Focused Ultrasound for Noninvasive Neuromodulation of the Visual Cortex.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control 01, 2021 | Pubmed ID: 32746196

Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE Dysfunction.

Investigative ophthalmology & visual science 09, 2020 | Pubmed ID: 32945842

Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.

Scientific reports 03, 2021 | Pubmed ID: 33737600

Stem Cell-based Treatment Strategies for Degenerative Diseases of the Retina.

Current stem cell research & therapy , 2022 | Pubmed ID: 34348629

Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats.

Frontiers in neuroscience , 2021 | Pubmed ID: 34764853

Long-Term Transplant Effects of iPSC-RPE Monolayer in Immunodeficient RCS Rats.

Cells 10, 2021 | Pubmed ID: 34831174

Tissue Engineering Strategies for Retina Regeneration.

Applied sciences (Basel, Switzerland) Mar, 2021 | Pubmed ID: 35251703

INSTITUTIONS

University of Southern California

Keck School of Medicine of the University of Southern California

JOVE ARTICLES

Development of a Surgical Technique for Subretinal Implants in Rats

Juan Carlos Martinez Camarillo^1,2,

Yuntao Hu^1,5,

Biju B. Thomas^1,2,

Danhong Zhu³,

David R. Hinton^2,3,

Debbie Mitra^1,2,

Jose Miguel Mora Correa²,

Deepthi S. Rajendran Nair^1,2,

Jane Lebkowski⁴,

Mark S. Humayun^1,2

¹USC Roski Eye Institute, Keck School of Medicine of the University of Southern California,

²USC Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics, University of Southern California,

³Department of Pathology, Keck School of Medicine of the University of Southern California,

⁴, Regenerative Patch Technologies LLC,

⁵Eye center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University

Medicine

A New Optokinetic Testing Method to Measure Rat Vision

Faizah Ahmed^*,1,

Deepthi S. Rajendran Nair^*,1,

Biju B. Thomas^1,2

¹Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California,

²USC Ginsburg Institute for Biomedical Therapeutics, University of Southern California

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Biju B. Thomas

Roski Eye Institute,Department of Ophthalmology,Keck School of Medicine,USC Ginsburg Institute for Biomedical Therapeutics,USC Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics,Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine

University of Southern California

Development of a Surgical Technique for Subretinal Implants in Rats

A New Optokinetic Testing Method to Measure Rat Vision

Roski Eye Institute,
Department of Ophthalmology,
Keck School of Medicine,
USC Ginsburg Institute for Biomedical Therapeutics,
USC Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics,
Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine