USC Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics
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Contributions of Fas-Fas ligand interactions to the pathogenesis of mouse hepatitis virus in the central nervous system.
Journal of virology Mar, 2000 | Pubmed ID: 10666278
Kinetics of cytokine mRNA expression in the central nervous system following lethal and nonlethal coronavirus-induced acute encephalomyelitis.
Virology Jul, 1997 | Pubmed ID: 9217050
Expression of interferon-gamma by a coronavirus defective-interfering RNA vector and its effect on viral replication, spread, and pathogenicity.
Virology Jul, 1997 | Pubmed ID: 9217056
Expression of hemagglutinin/esterase by a mouse hepatitis virus coronavirus defective-interfering RNA alters viral pathogenesis.
Virology Mar, 1998 | Pubmed ID: 9501044
Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis.
The Journal of experimental medicine Mar, 1999 | Pubmed ID: 10075984
Viral induced demyelination.
Brain pathology (Zurich, Switzerland) Jan, 2001 | Pubmed ID: 11145206
Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants.
Current biology : CB Mar, 2002 | Pubmed ID: 11882291
Matrix metalloproteinase expression correlates with virulence following neurotropic mouse hepatitis virus infection.
Journal of virology Aug, 2002 | Pubmed ID: 12097550
Regulation of RPE intercellular junction integrity and function by hepatocyte growth factor.
Investigative ophthalmology & visual science Aug, 2002 | Pubmed ID: 12147616
The art of survival during viral persistence.
Journal of neurovirology Dec, 2002 | Pubmed ID: 12491152
Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2003 | Pubmed ID: 12626593
A role for connective tissue growth factor in the pathogenesis of choroidal neovascularization.
Archives of ophthalmology (Chicago, Ill. : 1960) Sep, 2003 | Pubmed ID: 12963611
Developmental retinal apoptosis in Ku86-/- mice.
DNA repair Dec, 2003 | Pubmed ID: 14642570
Hepatocyte growth factor and its role in the pathogenesis of retinal detachment.
Investigative ophthalmology & visual science Jan, 2004 | Pubmed ID: 14691191
Mouse strain-dependent heterogeneity of resting limbal vasculature.
Investigative ophthalmology & visual science Feb, 2004 | Pubmed ID: 14744883
Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cells.
Journal of virology Feb, 2004 | Pubmed ID: 14747539
Accumulation of NH2-terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy.
Diabetes care Mar, 2004 | Pubmed ID: 14988298
Gene therapy in a murine model for clinical application to multiple sclerosis.
Annals of neurology Mar, 2004 | Pubmed ID: 14991817
Ceramide-induced apoptosis: role of catalase and hepatocyte growth factor.
Free radical biology & medicine Jul, 2004 | Pubmed ID: 15203188
Differential regulation of primary and secondary CD8+ T cells in the central nervous system.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2004 | Pubmed ID: 15528365
Expression of a dominant negative IFN-gammareceptor on mouse oligodendrocytes.
Glia Jul, 2005 | Pubmed ID: 15779088
Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis.
Journal of virology Apr, 2005 | Pubmed ID: 15795262
Maintenance of CD8+ T cells during acute viral infection of the central nervous system requires CD4+ T cells but not interleukin-2.
Viral immunology , 2005 | Pubmed ID: 15802960
Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularization.
Laboratory investigation; a journal of technical methods and pathology Jun, 2005 | Pubmed ID: 15856049
A selective cyclic integrin antagonist blocks the integrin receptors alphavbeta3 and alphavbeta5 and inhibits retinal pigment epithelium cell attachment, migration and invasion.
BMC ophthalmology Jun, 2005 | Pubmed ID: 15987521
Neutrophils promote experimental choroidal neovascularization.
Molecular vision Jun, 2005 | Pubmed ID: 15988410
Protection from oxidative stress by methionine sulfoxide reductases in RPE cells.
Biochemical and biophysical research communications Aug, 2005 | Pubmed ID: 15993845
Astrocyte expression of a dominant-negative interferon-gamma receptor.
Journal of neuroscience research Oct, 2005 | Pubmed ID: 16118798
In vivo expression of GFP transgene delivered via a replicating feline leukemia virus.
Veterinary microbiology Oct, 2005 | Pubmed ID: 16143471
Sequential induction of angiogenic growth factors by TNF-alpha in choroidal endothelial cells.
Journal of neuroimmunology Feb, 2006 | Pubmed ID: 16288810
Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization.
Investigative ophthalmology & visual science Dec, 2005 | Pubmed ID: 16303978
Neuropilin-1 expression by endothelial cells and retinal pigment epithelial cells in choroidal neovascular membranes.
American journal of ophthalmology Dec, 2005 | Pubmed ID: 16376649
Characterization of brimonidine transport in retinal pigment epithelium.
Investigative ophthalmology & visual science Jan, 2006 | Pubmed ID: 16384975
CNS viral infection diverts homing of antibody-secreting cells from lymphoid organs to the CNS.
European journal of immunology Mar, 2006 | Pubmed ID: 16437540
Inhibition of interferon-gamma signaling in oligodendroglia delays coronavirus clearance without altering demyelination.
The American journal of pathology Mar, 2006 | Pubmed ID: 16507895
Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells.
Virology Jun, 2006 | Pubmed ID: 16510164
Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor.
Experimental eye research Jul, 2006 | Pubmed ID: 16563380
MMP-2 and MMP-9 secretion by rpe is stimulated by angiogenic molecules found in choroidal neovascular membranes.
Retina (Philadelphia, Pa.) Apr, 2006 | Pubmed ID: 16603966
Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina.
The American journal of pathology May, 2006 | Pubmed ID: 16651637
Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells.
Biochemical and biophysical research communications Aug, 2006 | Pubmed ID: 16793007
Altered neuroantigen-specific cytokine secretion in a Th2 environment reduces experimental autoimmune encephalomyelitis.
Journal of neuroimmunology Sep, 2006 | Pubmed ID: 16814872
Liver X receptor activation decreases the severity of experimental autoimmune encephalomyelitis.
Journal of neuroscience research Nov, 2006 | Pubmed ID: 16955483
Population-based study of early age-related macular degeneration: role of the complement factor H Y402H polymorphism in bilateral but not unilateral disease.
Ophthalmology Jan, 2007 | Pubmed ID: 17198853
Stimulation of apical and basolateral VEGF-A and VEGF-C secretion by oxidative stress in polarized retinal pigment epithelial cells.
Molecular vision Dec, 2006 | Pubmed ID: 17200665
Thrombospondin-1 expression in RPE and choroidal neovascular membranes.
Yan ke xue bao = Eye science Dec, 2006 | Pubmed ID: 17378161
In vivo models of proliferative vitreoretinopathy.
Nature protocols , 2007 | Pubmed ID: 17401340
alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress.
Molecular vision Apr, 2007 | Pubmed ID: 17438522
Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells.
Journal of virology Jan, 2008 | Pubmed ID: 17928334
CD4 T cells contribute to virus control and pathology following central nervous system infection with neurotropic mouse hepatitis virus.
Journal of virology Mar, 2008 | Pubmed ID: 18094171
Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia.
Experimental eye research Feb, 2008 | Pubmed ID: 18191123
Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie May, 2008 | Pubmed ID: 18278507
N-(4-hydroxyphenyl) retinamide augments laser-induced choroidal neovascularization in mice.
Investigative ophthalmology & visual science Mar, 2008 | Pubmed ID: 18326751
Connective tissue growth factor as a mediator of intraocular fibrosis.
Investigative ophthalmology & visual science Sep, 2008 | Pubmed ID: 18450591
The immune response to herpes simplex virus type 1 infection in susceptible mice is a major cause of central nervous system pathology resulting in fatal encephalitis.
Journal of virology Jul, 2008 | Pubmed ID: 18480436
Paclitaxel Induces Apoptosis in AIDS-Related Kaposi's Sarcoma Cells.
Sarcoma , 2000 | Pubmed ID: 18521433
Toll-like receptor 3 and geographic atrophy in age-related macular degeneration.
The New England journal of medicine Oct, 2008 | Pubmed ID: 18753640
Memory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis.
Journal of virology Dec, 2008 | Pubmed ID: 18842712
Regulation of thioredoxin by ceramide in retinal pigment epithelial cells.
Experimental eye research Mar, 2009 | Pubmed ID: 18996115
Immunocytochemical analysis of retinal neurons under electrical stimulation.
Brain research Feb, 2009 | Pubmed ID: 19103179
BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration.
The Journal of biological chemistry Apr, 2009 | Pubmed ID: 19158083
Regulated secretion of complement factor H by RPE and its role in RPE migration.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie May, 2009 | Pubmed ID: 19214553
A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells.
Nature protocols , 2009 | Pubmed ID: 19373231
Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells.
Investigative ophthalmology & visual science Jan, 2010 | Pubmed ID: 19643969
Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro.
Investigative ophthalmology & visual science Jan, 2010 | Pubmed ID: 19696168
Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration.
Vision research Mar, 2010 | Pubmed ID: 19765607
RNase L mediated protection from virus induced demyelination.
PLoS pathogens Oct, 2009 | Pubmed ID: 19798426
Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis.
Cell death and differentiation Mar, 2010 | Pubmed ID: 19816510
alphaB-crystallin regulation of angiogenesis by modulation of VEGF.
Blood Apr, 2010 | Pubmed ID: 20023214
Gamma interferon signaling in oligodendrocytes is critical for protection from neurotropic coronavirus infection.
Journal of virology Mar, 2010 | Pubmed ID: 20042510
What determines the switch between atrophic and neovascular forms of age related macular degeneration? - the role of BMP4 induced senescence.
Aging Aug, 2009 | Pubmed ID: 20157553
Neutrophils compromise retinal pigment epithelial barrier integrity.
Journal of biomedicine & biotechnology , 2010 | Pubmed ID: 20204129
Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: relevance to age-related macular degeneration.
Aging Dec, 2009 | Pubmed ID: 20228934
Recombinant human VEGF165b inhibits experimental choroidal neovascularization.
Investigative ophthalmology & visual science Aug, 2010 | Pubmed ID: 20237252
Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2010 | Pubmed ID: 20876353
Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species.
Journal of neuroscience research Dec, 2010 | Pubmed ID: 20936703
αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells.
PloS one Oct, 2010 | Pubmed ID: 20949024
Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis.
The American journal of pathology Dec, 2010 | Pubmed ID: 20971738
Vitreal oxygenation in retinal ischemia reperfusion.
Investigative ophthalmology & visual science Feb, 2011 | Pubmed ID: 21051734
Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival.
Investigative ophthalmology & visual science Mar, 2011 | Pubmed ID: 21087957
Factors supporting intrathecal humoral responses following viral encephalomyelitis.
Journal of virology Mar, 2011 | Pubmed ID: 21191015
Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis.
Biochemical and biophysical research communications Feb, 2011 | Pubmed ID: 21219868
Sonoporation enhances chemotherapeutic efficacy in retinoblastoma cells in vitro.
Investigative ophthalmology & visual science May, 2011 | Pubmed ID: 21273549
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.
Nature Mar, 2011 | Pubmed ID: 21297615
Antenatal maternal stress alters functional brain responses in adult offspring during conditioned fear.
Brain research Apr, 2011 | Pubmed ID: 21300034
Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2011 | Pubmed ID: 21411747
CXCR3-dependent plasma blast migration to the central nervous system during viral encephalomyelitis.
Journal of virology Jul, 2011 | Pubmed ID: 21507985
Shifting hierarchies of interleukin-10-producing T cell populations in the central nervous system during acute and persistent viral encephalomyelitis.
Journal of virology Jul, 2011 | Pubmed ID: 21525347
Regulation of fibronectin-EDA through CTGF domain-specific interactions with TGFβ2 and its receptor TGFβRII.
Investigative ophthalmology & visual science Jul, 2011 | Pubmed ID: 21571675
Methionine sulfoxide reductase A: Structure, function and role in ocular pathology.
World journal of biological chemistry Aug, 2011 | Pubmed ID: 21909460
VEGF and PEDF secretion in ARPE-19 and fhRPE cells.
Investigative ophthalmology & visual science Nov, 2011 | Pubmed ID: 22104197
WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.
Cancer cell Dec, 2011 | Pubmed ID: 22172722
CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis.
Journal of virology Mar, 2012 | Pubmed ID: 22205741
Over-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9.
Angiogenesis Jun, 2012 | Pubmed ID: 22392094
Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux.
PloS one , 2012 | Pubmed ID: 22442691
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.
Cell May, 2012 | Pubmed ID: 22541070
IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils.
Journal of neuroinflammation May, 2012 | Pubmed ID: 22642802
Novel roles for α-crystallins in retinal function and disease.
Progress in retinal and eye research Nov, 2012 | Pubmed ID: 22721717
Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction.
Free radical biology & medicine Sep, 2012 | Pubmed ID: 22781655
IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability.
PloS one , 2012 | Pubmed ID: 22848713
A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer.
Ophthalmic research , 2012 | Pubmed ID: 22868580
ERK1/2 activation is a therapeutic target in age-related macular degeneration.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2012 | Pubmed ID: 22869729
Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε.
The Journal of biological chemistry Oct, 2012 | Pubmed ID: 22879598
Angiofibrotic response to vascular endothelial growth factor inhibition in diabetic retinal detachment: report no. 1.
Archives of ophthalmology (Chicago, Ill. : 1960) Sep, 2012 | Pubmed ID: 22965588
GRP78 plays an essential role in adipogenesis and postnatal growth in mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Mar, 2013 | Pubmed ID: 23180827
Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis.
Journal of neuroinflammation Dec, 2012 | Pubmed ID: 23237504
Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis.
Journal of virology Mar, 2013 | Pubmed ID: 23302888
Antiapoptotic properties of α-crystallin-derived peptide chaperones and characterization of their uptake transporters in human RPE cells.
Investigative ophthalmology & visual science Apr, 2013 | Pubmed ID: 23532520
Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer.
Investigative ophthalmology & visual science Jul, 2013 | Pubmed ID: 23833067
IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis.
Journal of neuroimmunology Oct, 2013 | Pubmed ID: 23992866
TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy.
Investigative ophthalmology & visual science Nov, 2013 | Pubmed ID: 24114535
MMP-independent role of TIMP-1 at the blood brain barrier during viral encephalomyelitis.
ASN neuro Nov, 2013 | Pubmed ID: 24156369
Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages.
Journal of virology Jan, 2014 | Pubmed ID: 24198415
Role of CD25(+) CD4(+) T cells in acute and persistent coronavirus infection of the central nervous system.
Virology Dec, 2013 | Pubmed ID: 24210105
PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis.
Journal of neuroimmunology May, 2014 | Pubmed ID: 24642385
Ceramide inhibits connective tissue growth factor expression by human retinal pigment epithelial cells.
Cytokine Aug, 2014 | Pubmed ID: 24758915
Protein polymer nanoparticles engineered as chaperones protect against apoptosis in human retinal pigment epithelial cells.
Journal of controlled release : official journal of the Controlled Release Society Oct, 2014 | Pubmed ID: 24780268
Protection of retina by αB crystallin in sodium iodate induced retinal degeneration.
PloS one , 2014 | Pubmed ID: 24874187
IL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2014 | Pubmed ID: 24890725
Distinct CD4 T-cell effects on primary versus recall CD8 T-cell responses during viral encephalomyelitis.
Immunology Mar, 2015 | Pubmed ID: 25187405
DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2014 | Pubmed ID: 25349431
Pharmacological protection of retinal pigmented epithelial cells by sulindac involves PPAR-α.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2014 | Pubmed ID: 25385631
Polarized human embryonic stem cell-derived retinal pigment epithelial cell monolayers have higher resistance to oxidative stress-induced cell death than nonpolarized cultures.
Stem cells translational medicine Jan, 2015 | Pubmed ID: 25411476
Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity.
Science (New York, N.Y.) Nov, 2014 | Pubmed ID: 25414314
IL-18 is not therapeutic for neovascular age-related macular degeneration.
Nature medicine Dec, 2014 | Pubmed ID: 25473914
TGF-β2 secretion from RPE decreases with polarization and becomes apically oriented.
Cytokine Feb, 2015 | Pubmed ID: 25496702
Sodium iodate induced retinal degeneration: new insights from an old model.
Neural regeneration research Dec, 2014 | Pubmed ID: 25657718
Molecular mechanisms of subretinal fibrosis in age-related macular degeneration.
Experimental eye research Jan, 2016 | Pubmed ID: 25773985
Attenuation of choroidal neovascularization by histone deacetylase inhibitor.
PloS one , 2015 | Pubmed ID: 25807249
Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis.
Journal of neuroinflammation Apr, 2015 | Pubmed ID: 25896970
Alpha crystallins in the retinal pigment epithelium and implications for the pathogenesis and treatment of age-related macular degeneration.
Biochimica et biophysica acta Jan, 2016 | Pubmed ID: 26026469
Stem cell based therapies for age-related macular degeneration: The promises and the challenges.
Progress in retinal and eye research Sep, 2015 | Pubmed ID: 26113213
Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination.
Glia Nov, 2015 | Pubmed ID: 26132901
Myd88 Initiates Early Innate Immune Responses and Promotes CD4 T Cells during Coronavirus Encephalomyelitis.
Journal of virology Sep, 2015 | Pubmed ID: 26136579
SIRT1 mediated inhibition of VEGF/VEGFR2 signaling by Resveratrol and its relevance to choroidal neovascularization.
Cytokine Dec, 2015 | Pubmed ID: 26174951
Inhibition of DNA Methylation and Methyl-CpG-Binding Protein 2 Suppresses RPE Transdifferentiation: Relevance to Proliferative Vitreoretinopathy.
Investigative ophthalmology & visual science Aug, 2015 | Pubmed ID: 26305530
Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy.
Scientific reports Nov, 2015 | Pubmed ID: 26552368
Aqueous Angiography: Real-Time and Physiologic Aqueous Humor Outflow Imaging.
PloS one , 2016 | Pubmed ID: 26807586
αB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition.
The American journal of pathology Apr, 2016 | Pubmed ID: 26878210
Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis.
Journal of neuroinflammation Feb, 2016 | Pubmed ID: 26906225
The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction.
Investigative ophthalmology & visual science Mar, 2016 | Pubmed ID: 26990160
Targeting of exon VI-skipping human RGR-opsin to the plasma membrane of pigment epithelium and co-localization with terminal complement complex C5b-9.
Molecular vision , 2016 | Pubmed ID: 27011730
Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats.
Investigative ophthalmology & visual science 05, 2016 | Pubmed ID: 27233037
Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Aug, 2016 | Pubmed ID: 27335025
Aqueous Angiography-Mediated Guidance of Trabecular Bypass Improves Angiographic Outflow in Human Enucleated Eyes.
Investigative ophthalmology & visual science 09, 2016 | Pubmed ID: 27588614
Differential Regulation of Self-reactive CD4 T Cells in Cervical Lymph Nodes and Central Nervous System during Viral Encephalomyelitis.
Frontiers in immunology , 2016 | Pubmed ID: 27708643
Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione.
PloS one , 2016 | Pubmed ID: 27783653
Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes.
Translational vision science & technology Nov, 2016 | Pubmed ID: 27847692
Endoplasmic reticulum-mitochondrial crosstalk: a novel role for the mitochondrial peptide humanin.
Neural regeneration research Jan, 2017 | Pubmed ID: 28250736
Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer's disease.
JCI insight Aug, 2017 | Pubmed ID: 28814675
Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells.
Oxidative medicine and cellular longevity , 2017 | Pubmed ID: 28814984
Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models.
Stem cells international , 2017 | Pubmed ID: 28928775
Development of a new tissue injector for subretinal transplantation of human embryonic stem cell derived retinal pigmented epithelium.
International journal of retina and vitreous , 2017 | Pubmed ID: 29093829
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.
Nature medicine Jan, 2018 | Pubmed ID: 29176737
APOPTOSIS AND ANGIOFIBROSIS IN DIABETIC TRACTIONAL MEMBRANES AFTER VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITION: Results of a Prospective Trial. Report No. 2.
Retina (Philadelphia, Pa.) Feb, 2019 | Pubmed ID: 29190236
A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.
Science translational medicine 04, 2018 | Pubmed ID: 29618560
Intra-vitreal αB crystallin fused to elastin-like polypeptide provides neuroprotection in a mouse model of age-related macular degeneration.
Journal of controlled release : official journal of the Controlled Release Society Aug, 2018 | Pubmed ID: 29778783
Mechanism of cytokinesis failure in ovarian cystadenomas with defective BRCA1 and P53 pathways.
International journal of cancer Dec, 2018 | Pubmed ID: 29978915
A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Nov, 2018 | Pubmed ID: 30215097
Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells.
Investigative ophthalmology & visual science Feb, 2019 | Pubmed ID: 30707752
Histopathologic Assessment of Optic Nerves and Retina From a Patient With Chronically Implanted Argus II Retinal Prosthesis System.
Translational vision science & technology May, 2019 | Pubmed ID: 31171998
A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration.
International journal of molecular sciences Sep, 2019 | Pubmed ID: 31569695
Sympathetic Effects of Internal Carotid Nerve Manipulation on Choroidal Vascularity and Related Measures.
Investigative ophthalmology & visual science Oct, 2019 | Pubmed ID: 31618767
The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress.
Nanomedicine : nanotechnology, biology, and medicine Feb, 2020 | Pubmed ID: 31655204
Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study.
Ophthalmology. Retina Mar, 2020 | Pubmed ID: 31786135
Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina.
Acta neuropathologica May, 2020 | Pubmed ID: 32043162
The Emerging Role of Senescence in Ocular Disease.
Oxidative medicine and cellular longevity , 2020 | Pubmed ID: 32215170
Cytoplasmic synthesis of endogenous complementary DNA via reverse transcription and implications in age-related macular degeneration.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2021 | Pubmed ID: 33526699
Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.
Scientific reports 03, 2021 | Pubmed ID: 33737600
complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity.
Science advances Oct, 2021 | Pubmed ID: 34586848
One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration.
Translational vision science & technology Aug, 2021 | Pubmed ID: 34613357
Long-Term Transplant Effects of iPSC-RPE Monolayer in Immunodeficient RCS Rats.
Cells 10, 2021 | Pubmed ID: 34831174
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.
Science immunology Dec, 2021 | Pubmed ID: 34860583
Mechanisms of RPE senescence and potential role of αB crystallin peptide as a senolytic agent in experimental AMD.
Experimental eye research Feb, 2022 | Pubmed ID: 34986369
Blocking Ocular Sympathetic Activity Inhibits Choroidal Neovascularization.
Frontiers in neuroscience , 2021 | Pubmed ID: 35082594
Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration.
Stem cell reports Mar, 2022 | Pubmed ID: 35120620
Juan Carlos Martinez Camarillo1,2,
Yuntao Hu1,5,
Biju B. Thomas1,2,
Danhong Zhu3,
David R. Hinton2,3,
Debbie Mitra1,2,
Jose Miguel Mora Correa2,
Deepthi S. Rajendran Nair1,2,
Jane Lebkowski4,
Mark S. Humayun1,2
1USC Roski Eye Institute, Keck School of Medicine of the University of Southern California,
2USC Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics, University of Southern California,
3Department of Pathology, Keck School of Medicine of the University of Southern California,
4, Regenerative Patch Technologies LLC,
5Eye center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University
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