Clive N. May

Direct cardiac and vascular actions of adrenomedullin in conscious sheep.

Aldosterone acts on the kidney, not the brain, to cause mineralocorticoid hypertension in sheep.

Urotensin II acts centrally to increase epinephrine and ACTH release and cause potent inotropic and chronotropic actions.

Stimulation of cardiac sympathetic nerve activity by central angiotensinergic mechanisms in conscious sheep.

Selective vasodilator and chronotropic actions of 3',4'-dihydroxyflavonol in conscious sheep.

3',4'-Dihydroxyflavonol reduces infarct size and injury associated with myocardial ischaemia and reperfusion in sheep.

Oxytocinase/insulin-regulated aminopeptidase is distributed throughout the sheep, female reproductive tract and is regulated by oestrogen in the uterus.

Urotensin II, a novel peptide in central and peripheral cardiovascular control.

The haemodynamic and metabolic effects of epinephrine in experimental hyperdynamic septic shock.

Differential regional haemodynamic changes during mineralocorticoid hypertension.

Renal vascular resistance in sepsis.

The effect of normal saline resuscitation on vital organ blood flow in septic sheep.

Urinary biomarkers in septic acute kidney injury.

The histopathology of septic acute kidney injury: a systematic review.

Responses of cardiac sympathetic nerve activity to changes in circulating volume differ in normal and heart failure sheep.

Basis for the preferential activation of cardiac sympathetic nerve activity in heart failure.

Septic shock induces distinct changes in sympathetic nerve activity to the heart and kidney in conscious sheep.

3',4'-Dihydroxyflavonol improves post-ischaemic coronary endothelial function following 7days reperfusion in sheep.

Frontiers in research series: Neural, hormonal and renal interactions in long-term blood pressure control II. Introduction.

Angiotensin II in experimental hyperdynamic sepsis.

The impact of experimental hypoperfusion on subsequent kidney function.

Response of cardiac sympathetic nerve activity to intravenous irbesartan in heart failure.

Early and sustained systemic and renal hemodynamic effects of intravenous radiocontrast.

Hypertonic sodium resuscitation after hemorrhage improves hemodynamic function by stimulating cardiac, but not renal, sympathetic nerve activity.

The impact of intrarenal nitric oxide synthase inhibition on renal blood flow and function in mild and severe hyperdynamic sepsis.

Cardioprotection from ischaemia-reperfusion injury by a novel flavonol that reduces activation of p38 MAPK.

Renal bioenergetics during early gram-negative mammalian sepsis and angiotensin II infusion.

Central angiotensin type 1 receptor blockade decreases cardiac but not renal sympathetic nerve activity in heart failure.

The effects of terlipressin on regional hemodynamics and kidney function in experimental hyperdynamic sepsis.

The role of the paraventricular nucleus of the hypothalamus in the regulation of cardiac and renal sympathetic nerve activity in conscious normal and heart failure sheep.

Effect of selective inhibition of renal inducible nitric oxide synthase on renal blood flow and function in experimental hyperdynamic sepsis.

Pulmonary Artery Catheter (PAC) Accuracy and Efficacy Compared with Flow Probe and Transcutaneous Doppler (USCOM): An Ovine Cardiac Output Validation.

Novel targets for sepsis-induced kidney injury: the glomerular arterioles and the sympathetic nervous system.

Cardiac sympathoexcitation in heart failure.

Organ selective regulation of sympathetic outflow by the brain Angiotensin system.

Cardioprotective 3',4'-dihydroxyflavonol attenuation of JNK and p38(MAPK) signalling involves CaMKII inhibition.

Renal histopathology during experimental septic acute kidney injury and recovery.

Intracarotid hypertonic sodium chloride differentially modulates sympathetic nerve activity to the heart and kidney.

Systemic and renal haemodynamic effects of fluid bolus therapy: sodium chloride versus sodium octanoate-balanced solution.

Glomerular haemodynamics, the renal sympathetic nervous system and sepsis-induced acute kidney injury.

Effects of renal denervation on regional hemodynamics and kidney function in experimental hyperdynamic sepsis.

Role of prostaglandins in determining the increased cardiac sympathetic nerve activity in ovine sepsis.

Central exogenous nitric oxide decreases cardiac sympathetic drive and improves baroreflex control of heart rate in ovine heart failure.

Tonic arterial chemoreceptor activity contributes to cardiac sympathetic activation in mild ovine heart failure.

The low frequency power of heart rate variability is neither a measure of cardiac sympathetic tone nor of baroreflex sensitivity.

Reinnervation of renal afferent and efferent nerves at 5.5 and 11 months after catheter-based radiofrequency renal denervation in sheep.

Effects of selective β1-adrenoceptor blockade on cardiovascular and renal function and circulating cytokines in ovine hyperdynamic sepsis.

Reply to "Letter to the editor: Does low-frequency power of heart rate variability correlate with cardiac sympathetic tone in normal sheep?".

Reinnervation following catheter-based radio-frequency renal denervation.

Long-term measurement of renal cortical and medullary tissue oxygenation and perfusion in unanesthetized sheep.

Evidence that the MEK/ERK but not the PI3K/Akt pathway is required for protection from myocardial ischemia-reperfusion injury by 3',4'-dihydroxyflavonol.

Clonidine Restores Pressor Responsiveness to Phenylephrine and Angiotensin II in Ovine Sepsis.

Cortical and Medullary Tissue Perfusion and Oxygenation in Experimental Septic Acute Kidney Injury.

Acid-base changes after fluid bolus: sodium chloride vs. sodium octanoate.

Systemic and renal hemodynamic effects of intra-arterial radiocontrast.

Variable responses of regional renal oxygenation and perfusion to vasoactive agents in awake sheep.

Role of endothelin-1 in mediating changes in cardiac sympathetic nerve activity in heart failure.

The role of the renal afferent and efferent nerve fibers in heart failure.

Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity.

Intrarenal and urinary oxygenation during norepinephrine resuscitation in ovine septic acute kidney injury.

Chronic impedance spectroscopy of an endovascular stent-electrode array.

Catheter-Based Renal Denervation Exacerbates Blood Pressure Fall During Hemorrhage.

Recording sympathetic nerve activity in conscious humans and other mammals: guidelines and the road to standardization.

An ovine model of cerebral catheter venography for implantation of an endovascular neural interface.

The ovine motor cortex: A review of functional mapping and cytoarchitecture.

Circumventing a broken heart: cytokines and the subfornical organ.

Urinary Oxygenation as a Surrogate Measure of Medullary Oxygenation During Angiotensin II Therapy in Septic Acute Kidney Injury.

Differential effects of isotonic and hypotonic 4% albumin solution on intracranial pressure and renal perfusion and function.

An Ovine Model for Studying the Pathophysiology of Septic Acute Kidney Injury.

Effects of Clonidine on the Cardiovascular, Renal, and Inflammatory Responses to Experimental Bacteremia.

Role of the Sympathetic Nervous System and Its Modulation in Renal Hypertension.

Mechanisms underlying the increased cardiac norepinephrine spillover in heart failure.

Adeno-Associated Virus Gene Therapy: Translational Progress and Future Prospects in the Treatment of Heart Failure.

Signal quality of simultaneously recorded endovascular, subdural and epidural signals are comparable.

Sepsis-induced acute kidney injury: A disease of the microcirculation.

Zinc preconditioning protects against renal ischaemia reperfusion injury in a preclinical sheep large animal model.

Increased cardiac sympathetic nerve activity in ovine heart failure is reduced by lesion of the area postrema, but not lamina terminalis.

Alterations in regional kidney oxygenation during expansion of extracellular fluid volume in conscious healthy sheep.

In renovascular hypertension, TNF-α type-1 receptors in the area postrema mediate increases in cardiac and renal sympathetic nerve activity and blood pressure.

Effects of Fluid Bolus Therapy on Renal Perfusion, Oxygenation, and Function in Early Experimental Septic Kidney Injury.

Author Correction: Signal quality of simultaneously recorded endovascular, subdural and epidural signals are comparable.

Sustained Decrease in Blood Pressure and Reduced Anatomical and Functional Reinnervation of Renal Nerves in Hypertensive Sheep 30 Months After Catheter-Based Renal Denervation.

Renal perfusion, oxygenation, and sympathetic nerve activity during volatile or intravenous general anaesthesia in sheep.

Renal Cortical Perfusion, Measured by Superb Microvascular Imaging, during Infusion of Norepinephrine in Experimental Cardiopulmonary Bypass.

Carotid artery and cerebral blood flow during experimental cardiopulmonary resuscitation: A systematic review of the literature.

Strategies that improve renal medullary oxygenation during experimental cardiopulmonary bypass may mitigate postoperative acute kidney injury.

Focal stimulation of the sheep motor cortex with a chronically implanted minimally invasive electrode array mounted on an endovascular stent.

Factors that confound the prediction of renal medullary oxygenation and risk of acute kidney injury from measurement of bladder urine oxygen tension.

Furosemide reverses medullary tissue hypoxia in ovine septic acute kidney injury.

Blunted diuretic and natriuretic responses to acute sodium loading early after catheter-based renal denervation in normotensive sheep.

Renal Denervation Update From the International Sympathetic Nervous System Summit: JACC State-of-the-Art Review.

Neurohumoral interactions contributing to renal vasoconstriction and decreased renal blood flow in heart failure.

Effect of Furosemide on Urinary Oxygenation in Patients with Septic Shock.

Intrathecal Administration of Losartan Reduces Directly Recorded Cardiac Sympathetic Nerve Activity in Ovine Heart Failure.

Chemoattraction and Recruitment of Activated Immune Cells, Central Autonomic Control, and Blood Pressure Regulation.

Dexmedetomidine reduces norepinephrine requirements and preserves renal oxygenation and function in ovine septic acute kidney injury.

Renal hemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep under total intravenous anesthesia.

Renal Medullary Hypoxia: A New Therapeutic Target for Septic Acute Kidney Injury?

Systemic administration of pentoxifylline attenuates the development of hypertension in renovascular hypertensive rats.

Systemic haemodynamic, renal perfusion and renal oxygenation responses to changes in inspired oxygen fraction during total intravenous or volatile anaesthesia.

Sympathetic nerves control bacterial clearance.

Beneficial Effects of Vasopressin Compared With Norepinephrine on Renal Perfusion, Oxygenation, and Function in Experimental Septic Acute Kidney Injury.

Renal functional reserve: from physiological phenomenon to clinical biomarker and beyond.

Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human experience.

Selective optogenetic stimulation of efferent fibers in the vagus nerve of a large mammal.

Influence of blood haemoglobin concentration on renal haemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep.

Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C.

Emerging benefits and drawbacks of α -adrenoceptor agonists in the management of sepsis and critical illness.

Increase in Bioavailability of Nitric Oxide After Renal Denervation Improves Kidney Function in Sheep With Hypertensive Kidney Disease.

The authors reply.

Urinary and renal oxygenation during dexmedetomidine infusion in critically ill adults with mechanistic insights from an ovine model.

Dynamic responses of renal oxygenation at the onset of cardiopulmonary bypass in sheep and man.

Therapeutic potential of megadose vitamin C to reverse organ dysfunction in sepsis and COVID-19.

Blunted natriuretic response to saline loading in sheep with hypertensive kidney disease following radiofrequency catheter-based renal denervation.

Renal, Cardiac, and Autonomic Effects of Catheter-Based Renal Denervation in Ovine Heart Failure.

Reversal of renal tissue hypoxia during experimental cardiopulmonary bypass in sheep by increased pump flow and arterial pressure.

Targeting Oxidative Stress in Septic Acute Kidney Injury: From Theory to Practice.

Renal Denervation in Combination With Angiotensin Receptor Blockade Prolongs Blood Pressure Trough During Hemorrhage.