Giovanna Tosato

B cell differentiation and immunoregulatory T cell function in human cord blood lymphocytes.

Interferon-inducible protein-10 identified as a mediator of tumor necrosis in vivo.

Interleukin-18, interferon-gamma, IP-10, and Mig expression in Epstein-Barr virus-induced infectious mononucleosis and posttransplant lymphoproliferative disease.

Laminin binding to the calreticulin fragment vasostatin regulates endothelial cell function.

Anti-tumor activities of the angiogenesis inhibitors interferon-inducible protein-10 and the calreticulin fragment vasostatin.

Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma.

Pathogenesis and manifestations of human herpesvirus-8-associated disorders.

Viral and cellular cytokines as therapeutic targets in AIDS-related lymphoproliferative disorders.

Targeted inhibition of angiogenic factors in AIDS-related disorders.

Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis.

Insulin-like growth factor I induces migration and invasion of human multiple myeloma cells.

Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity.

HIV-1 Tat enhances Kaposi sarcoma-associated herpesvirus (KSHV) infectivity.

Derivation of endothelial cells from CD34- umbilical cord blood.

Therapeutic options for human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus-related disorders.

Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2.

Neoplastic conditions in the context of HIV-1 infection.

Role of human cripto-1 in tumor angiogenesis.

Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1alpha in the circulation.

B-cell recovery following rituximab-based therapy is associated with perturbations in stromal derived factor-1 and granulocyte homeostasis.

Therapy insight: AIDS-related malignancies--the influence of antiviral therapy on pathogenesis and management.

Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function.

Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A.

Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma.

G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells.

EphB2 and EphB4 receptors forward signaling promotes SDF-1-induced endothelial cell chemotaxis and branching remodeling.

FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc.

Transcription factor Gfi-1 induced by G-CSF is a negative regulator of CXCR4 in myeloid cells.

Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A.

Dll4 activation of Notch signaling reduces tumor vascularity and inhibits tumor growth.

Palmitoylation controls recycling in lysosomal sorting and trafficking.

Gene regulation and functional alterations induced by Kaposi's sarcoma-associated herpesvirus-encoded ORFK13/vFLIP in endothelial cells.

EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures.

Targeting the mammalian target of Rapamycin to inhibit VEGF and cytokines for the treatment of primary effusion lymphoma.

Regulation of angiogenesis in malignancies associated with Epstein-Barr virus and Kaposi's sarcoma-associated herpes virus.

The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis.

Impaired recruitment of Grk6 and beta-Arrestin 2 causes delayed internalization and desensitization of a WHIM syndrome-associated CXCR4 mutant receptor.

The transcription factor Gfi1 regulates G-CSF signaling and neutrophil development through the Ras activator RasGRP1.

An interleukin-6-related systemic inflammatory syndrome in patients co-infected with Kaposi sarcoma-associated herpesvirus and HIV but without Multicentric Castleman disease.

Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis.

NF-kappaB activation stimulates transcription and replication of retrovirus XMRV in human B-lineage and prostate carcinoma cells.

Adult human circulating CD34⁻Lin⁻CD45⁻CD133⁻ cells can differentiate into hematopoietic and endothelial cells.

Viral interleukin-6: role in Kaposi's sarcoma-associated herpesvirus: associated malignancies.

PEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinity.

HHV-8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice.

Semaphorin 6A regulates angiogenesis by modulating VEGF signaling.

Human herpesvirus 8+ polyclonal IgMλ B-cell lymphocytosis mimicking plasmablastic leukemia/lymphoma in HIV-infected patients.

Attenuation of eph receptor kinase activation in cancer cells by coexpressed ephrin ligands.

Tumor-infiltrating myeloid cells activate Dll4/Notch/TGF-β signaling to drive malignant progression.

Notch and TGFβ: Functional partners facilitating tumor progression.

Contribution of viral mimics of cellular genes to KSHV infection and disease.

GRANULOCYTE INFILTRATION AND EXPRESSION OF THE PRO-ANGIOGENIC BV8 PROTEIN IN EXPERIMENTAL EL4 AND LEWIS LUNG CARCINOMA TUMORS.

EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.

Induction of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interleukin-6 by X-Box Binding Protein 1.

Clinical Features and Outcomes of Patients With Symptomatic Kaposi Sarcoma Herpesvirus (KSHV)-associated Inflammation: Prospective Characterization of KSHV Inflammatory Cytokine Syndrome (KICS).

Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling.

EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta.

Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration.

Evidence for a Mesothelial Origin of Body Cavity Effusion Lymphomas.

Ephrin ligands and Eph receptors contribution to hematopoiesis.

Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression.

Novel insights into endothelial cell malignancies.

DLC1 deficiency and YAP signaling drive endothelial cell contact inhibition of growth and tumorigenesis.

Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma.

Vasculopathy and Coagulopathy Associated with SARS-CoV-2 Infection.

Iterative epigenomic analyses in the same single cell.

Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth.

Bone marrow niches in myelodysplastic syndromes.