Center for Theoretical Problems of Physicochemical Pharmacology
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Blood coagulation and propagation of autowaves in flow.
Pathophysiology of haemostasis and thrombosis , 2005 | Pubmed ID: 16432314
On propagation of excitation waves in moving media: the FitzHugh-Nagumo model.
PloS one , 2009 | Pubmed ID: 19212435
Task-oriented modular decomposition of biological networks: trigger mechanism in blood coagulation.
Biophysical journal May, 2010 | Pubmed ID: 20441738
Lymph node cortical sinus organization and relationship to lymphocyte egress dynamics and antigen exposure.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2010 | Pubmed ID: 21059923
Identification of signal transduction pathways involved in the formation of platelet subpopulations upon activation.
British journal of haematology Apr, 2012 | Pubmed ID: 23379894
Circulating contact-pathway-activating microparticles together with factors IXa and XIa induce spontaneous clotting in plasma of hematology and cardiologic patients.
PloS one , 2014 | Pubmed ID: 24498168
Interactions outside the proteinase-binding loop contribute significantly to the inhibition of activated coagulation factor XII by its canonical inhibitor from corn.
The Journal of biological chemistry May, 2014 | Pubmed ID: 24706752
Hemostasis and thrombosis beyond biochemistry: roles of geometry, flow and diffusion.
Thrombosis research Oct, 2015 | Pubmed ID: 26278966
Continuous Modeling of Arterial Platelet Thrombus Formation Using a Spatial Adsorption Equation.
PloS one , 2015 | Pubmed ID: 26517377
New Infestin-4 Mutants with Increased Selectivity against Factor XIIa.
PloS one , 2015 | Pubmed ID: 26670620
Substrate delivery mechanism and the role of membrane curvature in factor X activation by extrinsic tenase.
Journal of theoretical biology 12, 2017 | Pubmed ID: 28935233
Mathematical Techniques for Understanding Platelet Regulation and the Development of New Pharmacological Approaches.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 30171583
Quantitative dynamics of reversible platelet aggregation: mathematical modelling and experiments.
Scientific reports 04, 2019 | Pubmed ID: 30996289
Mechanisms of increased mitochondria-dependent necrosis in Wiskott-Aldrich syndrome platelets.
Haematologica 04, 2020 | Pubmed ID: 31278208
In vitro flow based systems to study platelet function and thrombus formation: Recommendations for standardization: Communication from the SSC on Biorheology of the ISTH.
Journal of thrombosis and haemostasis : JTH 03, 2020 | Pubmed ID: 32112535
Differential Drug Target Selection in Blood Coagulation: What can we get from Computational Systems Biology Models?
Current pharmaceutical design , 2020 | Pubmed ID: 32250213
Heterogeneity of Integrin αβ Function in Pediatric Immune Thrombocytopenia Revealed by Continuous Flow Cytometry Analysis.
International journal of molecular sciences Apr, 2020 | Pubmed ID: 32344835
Control of Platelet CLEC-2-Mediated Activation by Receptor Clustering and Tyrosine Kinase Signaling.
Biophysical journal 06, 2020 | Pubmed ID: 32396849
Platelet function and bleeding in chronic lymphocytic leukemia and mantle cell lymphoma patients on ibrutinib.
Journal of thrombosis and haemostasis : JTH 10, 2020 | Pubmed ID: 32511880
Development of a Simple Kinetic Mathematical Model of Aggregation of Particles or Clustering of Receptors.
Life (Basel, Switzerland) Jun, 2020 | Pubmed ID: 32604803
Redistribution of TPA Fluxes in the Presence of PAI-1 Regulates Spatial Thrombolysis.
Biophysical journal 08, 2020 | Pubmed ID: 32653051
Effects of bacterial lipopolysaccharides on platelet function: inhibition of weak platelet activation.
Scientific reports 07, 2020 | Pubmed ID: 32704001
In Silico Hemostasis Modeling and Prediction.
Hamostaseologie Nov, 2020 | Pubmed ID: 32916753
Acylated 1-1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action.
Journal of medicinal chemistry 11, 2020 | Pubmed ID: 33089691
Modeling Thrombus Shell: Linking Adhesion Receptor Properties and Macroscopic Dynamics.
Biophysical journal 01, 2021 | Pubmed ID: 33472026
Asymmetrical Forces Dictate the Distribution and Morphology of Platelets in Blood Clots.
Cells Mar, 2021 | Pubmed ID: 33800866
Platelet function and bleeding at different phases of childhood immune thrombocytopenia.
Scientific reports 04, 2021 | Pubmed ID: 33931737
Hypochlorite-induced oxidation of fibrinogen: Effects on its thermal denaturation and fibrin structure.
Biochimica et biophysica acta. General subjects 10, 2021 | Pubmed ID: 34339807
Healthy pediatric platelets are moderately hyporeactive in comparison with adults' platelets.
Platelets Nov, 2021 | Pubmed ID: 34749589
Longitudinal multiparametric characterization of platelet dysfunction in COVID-19: Effects of disease severity, anticoagulation therapy and inflammatory status.
Thrombosis research 03, 2022 | Pubmed ID: 35066204
Ex vivo observation of granulocyte activity during thrombus formation.
BMC biology Feb, 2022 | Pubmed ID: 35125118
Nadezhda Podoplelova1,2,
Polina Soloveva1,4,
Andrei Garzon Dasgupta1,2,3,
Aleksandra Filkova1,2,
Mikhail Panteleev1,2,3,4
1Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences,
2, National Medical Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev,
3Faculty of Physics, Lomonosov Moscow State University,
4Faculty of Biological and Medical Physics, Moscow Institute of Physics and Technology
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