Masahito Ikawa

Innate versus learned odour processing in the mouse olfactory bulb.

Liver-specific γ-glutamyl carboxylase-deficient mice display bleeding diathesis and short life span.

Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies.

Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis.

Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.

TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa.

Genome Editing in Mouse Zygotes and Embryonic Stem Cells by Introducing SgRNA/Cas9 Expressing Plasmids.

Placenta-specific gene manipulation using lentiviral vector and its application.

Human Globozoospermia-Related Gene Spata16 Is Required for Sperm Formation Revealed by CRISPR/Cas9-Mediated Mouse Models.

Factors controlling sperm migration through the oviduct revealed by gene-modified mouse models.

Sperm-borne phospholipase C zeta-1 ensures monospermic fertilization in mice.

Chimeric analysis with newly established EGFP/DsRed2-tagged ES cells identify HYDIN as essential for spermiogenesis in mice.

Engineered CRISPR-Cas9 nuclease with expanded targeting space.

New Insights into the Molecular Events of Mammalian Fertilization.

RSPH6A is required for sperm flagellum formation and male fertility in mice.

Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice.

PTBP1 contributes to spermatogenesis through regulation of proliferation in spermatogonia.

Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity†.

An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility.

Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis.

Lvrn expression is not critical for mouse placentation.

CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†.

Calaxin is required for cilia-driven determination of vertebrate laterality.

Erratum: Publisher Correction: Calaxin is required for cilia-driven determination of vertebrate laterality.

Physiological function of seminal vesicle secretions on male fecundity.

The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility†.

Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice.

Male mice, caged in the International Space Station for 35 days, sire healthy offspring.

Genetic mutation of Frem3 does not causeFraser syndrome in mice.

Tesmin, Metallothionein-Like 5, is Required for Spermatogenesis in Mice†.

Nexin-Dynein regulatory complex component DRC7 but not FBXL13 is required for sperm flagellum formation and male fertility in mice.

Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa.

CRISPR/Cas9-Mediated Genome Editing Reveals Family Genes are Dispensable for Female Fertility in Mice.

Structural insights into tetraspanin CD9 function.

Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice.

Prss55 but not Prss51 is required for male fertility in mice†.

Knockout of serine-rich single-pass membrane protein 1 (Ssmem1) causes globozoospermia and sterility in male mice†.

Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice.

CIB4 is essential for the haploid phase of spermatogenesis in mice†.

NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility.

Tmprss12 is required for sperm motility and uterotubal junction migration in mice†.

Analysis of the sperm flagellar axoneme using gene-modified mice.

CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity.

CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†.

Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice†.

Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility.

RNA-binding protein Ptbp1 regulates alternative splicing and transcriptome in spermatogonia and maintains spermatogenesis in concert with Nanos3.

PHF7 Modulates BRDT Stability and Histone-to-Protamine Exchange during Spermiogenesis.

CRISPR/CAS9-mediated amino acid substitution reveals phosphorylation residues of RSPH6A are not essential for male fertility in mice†.

Astrocytic cAMP modulates memory via synaptic plasticity.

Protocol for isolation of spermatids from mouse testes.

ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility.

KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice.

Precise CAG repeat contraction in a Huntington's Disease mouse model is enabled by gene editing with SpCas9-NG.

CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice.

Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function.

Uterine Epithelial LIF Receptors Contribute to Implantation Chamber Formation in Blastocyst Attachment.

A sublethal ATP11A mutation associated with neurological deterioration causes aberrant phosphatidylcholine flipping in plasma membranes.

SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice.

The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum.

The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization.

LRRC23 is a conserved component of the radial spoke that is necessary for sperm motility and male fertility in mice.

FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice.

Sperm IZUMO1 Is Required for Binding Preceding Fusion With Oolemma in Mice and Rats.

Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.

Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish.

Proteolysis in Reproduction: Lessons From Gene-Modified Organism Studies.

IRGC1, a testis-enriched immunity related GTPase, is important for fibrous sheath integrity and sperm motility in mice.

TULP2 deletion mice exhibit abnormal outer dense fiber structure and male infertility.

Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice.