Department of Cell and Tissue Engineering
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A versatile modular bioreactor platform for Tissue Engineering.
Biotechnology journal Feb, 2017 | Pubmed ID: 27492568
Vascularised human tissue models: a new approach for the refinement of biomedical research.
Journal of biotechnology Jul, 2010 | Pubmed ID: 20399817
Raman spectroscopy as a tool for quality and sterility analysis for tissue engineering applications like cartilage transplants.
The International journal of artificial organs Apr, 2010 | Pubmed ID: 20458692
Electrospun poly(D/L-lactide-co-L-lactide) hybrid matrix: a novel scaffold material for soft tissue engineering.
Journal of materials science. Materials in medicine Sep, 2010 | Pubmed ID: 20640490
Stem cell microenvironments--unveiling the secret of how stem cell fate is defined.
Macromolecular bioscience Nov, 2010 | Pubmed ID: 20715131
The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine.
Biomaterials Oct, 2011 | Pubmed ID: 21764120
Raman spectroscopy: a noninvasive analysis tool for the discrimination of human skin cells.
Tissue engineering. Part C, Methods Oct, 2011 | Pubmed ID: 21774693
Raman spectroscopy for the non-contact and non-destructive monitoring of collagen damage within tissues.
Journal of biophotonics Jan, 2012 | Pubmed ID: 21954177
In situ guided tissue regeneration in musculoskeletal diseases and aging : Implementing pathology into tailored tissue engineering strategies.
Cell and tissue research Mar, 2012 | Pubmed ID: 22011785
Stem cell- and growth factor-based regenerative therapies for avascular necrosis of the femoral head.
Stem cell research & therapy , 2012 | Pubmed ID: 22356811
Oligonucleotide and Parylene Surface Coating of Polystyrene and ePTFE for Improved Endothelial Cell Attachment and Hemocompatibility.
International journal of biomaterials , 2012 | Pubmed ID: 22481939
Upcyte® microvascular endothelial cells repopulate decellularized scaffold.
Tissue engineering. Part C, Methods Jan, 2013 | Pubmed ID: 22799502
A bioreactor system for interfacial culture and physiological perfusion of vascularized tissue equivalents.
Biotechnology journal Mar, 2013 | Pubmed ID: 23047238
Ammonia plasma treatment of polystyrene surfaces enhances proliferation of primary human mesenchymal stem cells and human endothelial cells.
Biotechnology journal Mar, 2013 | Pubmed ID: 23070995
Bioreactors in tissue engineering - principles, applications and commercial constraints.
Biotechnology journal Mar, 2013 | Pubmed ID: 23161827
'Human-on-a-chip' developments: a translational cutting-edge alternative to systemic safety assessment and efficiency evaluation of substances in laboratory animals and man?
Alternatives to laboratory animals : ATLA Oct, 2012 | Pubmed ID: 23215661
Strategies in tissue engineering and regenerative medicine.
Biotechnology journal Mar, 2013 | Pubmed ID: 23460549
Bone tissue engineering in osteoporosis.
Maturitas Jun, 2013 | Pubmed ID: 23562167
Integrating biological vasculature into a multi-organ-chip microsystem.
Lab on a chip Sep, 2013 | Pubmed ID: 23743770
A human in vitro model that mimics the renal proximal tubule.
Tissue engineering. Part C, Methods Jul, 2014 | Pubmed ID: 24266327
Establishment of a human 3D lung cancer model based on a biological tissue matrix combined with a Boolean in silico model.
Molecular oncology Mar, 2014 | Pubmed ID: 24388494
An engineered 3D human airway mucosa model based on an SIS scaffold.
Biomaterials Aug, 2014 | Pubmed ID: 24912816
Host-integration of a tissue-engineered airway patch: two-year follow-up in a single patient.
Tissue engineering. Part A Feb, 2015 | Pubmed ID: 25316325
A perfusion bioreactor system efficiently generates cell-loaded bone substitute materials for addressing critical size bone defects.
Biotechnology journal Sep, 2015 | Pubmed ID: 26011163
In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells.
PloS one , 2015 | Pubmed ID: 26488607
Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies.
Pharmacology research & perspectives Oct, 2015 | Pubmed ID: 26516577
Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology.
ALTEX , 2015 | Pubmed ID: 26536291
Alternative methods for the replacement of eye irritation testing.
ALTEX , 2016 | Pubmed ID: 26626125
Differential Regulation of SOX9 Protein During Chondrogenesis of Induced Pluripotent Stem Cells Versus Mesenchymal Stromal Cells: A Shortcoming for Cartilage Formation.
Stem cells and development Mar, 2016 | Pubmed ID: 26906619
Activation of Myenteric Glia during Acute Inflammation In Vitro and In Vivo.
PloS one , 2016 | Pubmed ID: 26964064
Feasibility Study on a Microwave-Based Sensor for Measuring Hydration Level Using Human Skin Models.
PloS one , 2016 | Pubmed ID: 27046226
Catch-up validation study of an in vitro skin irritation test method based on an open source reconstructed epidermis (phase II).
Toxicology in vitro : an international journal published in association with BIBRA Oct, 2016 | Pubmed ID: 27435616
Human Organotypic Lung Tumor Models: Suitable For Preclinical 18F-FDG PET-Imaging.
PloS one , 2016 | Pubmed ID: 27501455
Human barrier models for the in vitro assessment of drug delivery.
Drug delivery and translational research Apr, 2017 | Pubmed ID: 27549106
In vitro chemotaxis and tissue remodeling assays quantitatively characterize foreign body reaction.
ALTEX , 2017 | Pubmed ID: 27725990
Ex vivo culture platform for assessment of cartilage repair treatment strategies.
ALTEX , 2017 | Pubmed ID: 27768805
Non-Coding RNAs in Lung Cancer: Contribution of Bioinformatics Analysis to the Development of Non-Invasive Diagnostic Tools.
Genes Dec, 2016 | Pubmed ID: 28035947
Three-Dimensional Coculture of Meniscal Cells and Mesenchymal Stem Cells in Collagen Type I Hydrogel on a Small Intestinal Matrix-A Pilot Study Toward Equine Meniscus Tissue Engineering.
Tissue engineering. Part A May, 2017 | Pubmed ID: 28095754
Osteogenesis and mineralization of mesenchymal stem cells in collagen type I-based recombinant peptide scaffolds.
Journal of biomedical materials research. Part A Jul, 2017 | Pubmed ID: 28247927
* An Injectable Recombinant Collagen I Peptide-Based Macroporous Microcarrier Allows Superior Expansion of C2C12 and Human Bone Marrow-Derived Mesenchymal Stromal Cells and Supports Deposition of Mineralized Matrix.
Tissue engineering. Part A Sep, 2017 | Pubmed ID: 28437178
A comparative multi-parametric in vitro model identifies the power of test conditions to predict the fibrotic tendency of a biomaterial.
Scientific reports May, 2017 | Pubmed ID: 28490729
Preparation of a Three-Dimensional Full Thickness Skin Equivalent.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28634944
Calcium fluoride based multifunctional nanoparticles for multimodal imaging.
Beilstein journal of nanotechnology , 2017 | Pubmed ID: 28900602
Advanced Therapy Medicinal Products: A Guide for Bone Marrow-derived MSC Application in Bone and Cartilage Tissue Engineering.
Tissue engineering. Part B, Reviews Dec, 2017 | Pubmed ID: 28990462
Fraunhofer Institute of Interfacial Engineering and Biotechnology (IGB) Stuttgart, Germany
Julius-Maximillians University, Würzburg, Germany
University Hospital Würzburg
Würzburg Branch of the Fraunhofer-Institute Interfacial Engineering and Biotechnology, IGB
University Hospital Wuerzburg
Fraunhofer Institute Interfacial Engineering and Biotechnology IGB
Institutsteil Würzburg
Universitätsklinikum Würzburg
Fraunhofer Institute for Silicate Research ISC
Miriam Votteler1,2,
Daniel A. Carvajal Berrio2,
Marieke Pudlas2,3,
Heike Walles2,4,
Katja Schenke-Layland1,2
1Department of Thoracic and Cardiovascular Surgery and Inter-University Centre for Medical Technology Stuttgart-Tübingen (IZST), Eberhard Karls University, Tübingen,
2Department of Cell and Tissue Engineering, Fraunhofer Institute of Interfacial Engineering and Biotechnology (IGB) Stuttgart, Germany,
3Department for Medical Interfacial Engineering (IGVT), University of Stuttgart, Germany,
4Institute of Tissue Engineering and Regenerative Medicine, Julius-Maximillians University, Würzburg, Germany
Claudia Göttlich*,1,
Lena C. Müller*,1,
Meik Kunz*,3,
Franziska Schmitt1,
Heike Walles1,4,
Thorsten Walles2,
Thomas Dandekar3,
Gudrun Dandekar1,4,
Sarah L. Nietzer1
1Department of Tissue Engineering and Regenerative Medicine (TERM), University Hospital Wuerzburg,
2Department of Cardiothoracic Surgery, University Hospital Wuerzburg,
3Department of Bioinformatics, University Wuerzburg,
4Translational Center Wuerzburg, Fraunhofer Institute Interfacial Engineering and Biotechnology IGB
Claudia Siverino1,
Barbara Tabisz2,
Tessa Lühmann3,
Lorenz Meinel3,
Thomas Müller4,
Heike Walles1,2,
Joachim Nickel1,2
1Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik (IGB), Translationszentrum Würzburg 'Regenerative Therapien für Krebs- und Muskuloskelettale Erkrankung', Institutsteil Würzburg,
2Lehrstuhl für Tissue Engineering und Regenerative Medizin, Universitätsklinikum Würzburg,
3Lehrstuhl für Pharmazeutische Technologie und Biopharmazie, Universität Würzburg,
4Lehrstuhl für molekulare Pflanzenphysiologie und Biophysik, Julius-von-Sachs Institut für Biowissenschaften, Universität Würzburg
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