Division of Hematology,
Department of Internal Medicine,
Medical School,
Division of Hematology, Department of Internal Medicine, Medical School
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Antagonistic effects of human cyclic MBP(87-99) altered peptide ligands in experimental allergic encephalomyelitis and human T-cell proliferation.
Journal of medicinal chemistry Jan, 2002 | Pubmed ID: 11784132
Adult chronic idiopathic thrombocytopenic purpura (ITP) is the manifestation of a type-1 polarized immune response.
Blood Apr, 2004 | Pubmed ID: 14670926
Type 1 and type 2 cytokine-producing CD4+ and CD8+ T cells in primary antiphospholipid syndrome.
Annals of hematology Nov, 2004 | Pubmed ID: 15300407
Leptin and its soluble receptor in plasma of patients suffering from remitting-relapsing multiple sclerosis (MS) In vitro effects of leptin on type-1 and type-2 cytokine secretion by peripheral blood mononuclear cells, T-cells and monocytes of MS patients.
Journal of autoimmunity Sep, 2004 | Pubmed ID: 15324935
Effect of splenectomy on type-1/type-2 cytokine gene expression in a patient with adult idiopathic thrombocytopenic purpura (ITP).
BMC blood disorders Oct, 2004 | Pubmed ID: 15491502
Defective tumor necrosis factor alpha-induced maturation of monocyte-derived dendritic cells in patients with myelodysplastic syndromes.
Clinical immunology (Orlando, Fla.) Dec, 2004 | Pubmed ID: 15507396
Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators.
Journal of medicinal chemistry Mar, 2005 | Pubmed ID: 15743189
Advances in the treatment of autoimmune diseases; cellular activity, type-1/type-2 cytokine secretion patterns and their modulation by therapeutic peptides.
Current medicinal chemistry , 2005 | Pubmed ID: 15974986
Immunotherapy for multiple sclerosis: basic insights for new clinical strategies.
Current neurovascular research Oct, 2004 | Pubmed ID: 16181082
Anti-TNF-alpha antibody therapies in autoimmune diseases.
Current topics in medicinal chemistry , 2006 | Pubmed ID: 17017952
Immunosuppressive drugs in HIV disease.
Current topics in medicinal chemistry , 2006 | Pubmed ID: 17017956
Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease.
Journal of medicinal chemistry Dec, 2008 | Pubmed ID: 19053745
Bronchial asthma, chronic obstructive pulmonary disease and NF-kappaB.
Current medicinal chemistry , 2009 | Pubmed ID: 19275599
A comparative biochemical analysis of glycosaminoglycans and proteoglycans in human orthotopic and heterotopic bone.
IUBMB life Apr, 2009 | Pubmed ID: 19319964
Expression patterns of leptin receptor (OB-R) isoforms and direct in vitro effects of recombinant leptin on OB-R, leptin expression and cytokine secretion by human hematopoietic malignant cells.
Cytokine Dec, 2009 | Pubmed ID: 19665393
Remitting-relapsing multiple sclerosis patient refractory to conventional treatments and bone marrow transplantation who responded to natalizumab.
International journal of general medicine Oct, 2010 | Pubmed ID: 21042570
Association of FOXP3 expression with non-small cell lung cancer.
Anticancer research May, 2011 | Pubmed ID: 21617226
T-lymphocyte subsets in peripheral blood and liver tissue of patients with chronic hepatitis B and C.
In vivo (Athens, Greece) , 2011 | Pubmed ID: 21753143
Long-term remission of recurrent herpes labialis following topical imiquimod application on distant healthy skin: a clinical and immunological study.
Antiviral therapy , 2011 | Pubmed ID: 21900718
Cord blood leptin levels of healthy neonates are associated with IFN-γ production by cord blood T-cells.
PloS one , 2012 | Pubmed ID: 22815836
Current therapeutic leads for the treatment of autoimmune diseases: stem cell transplantation and inhibition of post-translational modifications of autoantigens.
Expert opinion on drug discovery Oct, 2008 | Pubmed ID: 23489081
Conjugation with polyamines enhances the antibacterial and anticancer activity of chloramphenicol.
Nucleic acids research Jul, 2014 | Pubmed ID: 24939899
Cytokines as Biomarkers of Treatment Response to IFN β in Relapsing-Remitting Multiple Sclerosis.
Multiple sclerosis international , 2014 | Pubmed ID: 25152817
Chromium in drinking water: association with biomarkers of exposure and effect.
International journal of environmental research and public health Sep, 2014 | Pubmed ID: 25268509
Properties of myelin altered peptide ligand cyclo(87-99)(Ala91,Ala96)MBP87-99 render it a promising drug lead for immunotherapy of multiple sclerosis.
European journal of medicinal chemistry Aug, 2015 | Pubmed ID: 26112377
Circulating endotoxin and interleukin-6 levels are associated with Doppler-evaluated pulmonary vascular resistance in cirrhotic patients.
Hepatology international Oct, 2012 | Pubmed ID: 26201526
Synthesis and evaluation of chloramphenicol homodimers: molecular target, antimicrobial activity, and toxicity against human cells.
PloS one , 2015 | Pubmed ID: 26267355
T helper (Th)-cytokines in the urine of patients with primary glomerulonephritis treated with immunosuppressive drugs: Can they predict outcome?
Cytokine Dec, 2015 | Pubmed ID: 26307557
Immune Parameters That Distinguish Multiple Sclerosis Patients from Patients with Other Neurological Disorders at Presentation.
PloS one , 2015 | Pubmed ID: 26317430
HIV-1 subtype characteristics of infected persons living in southwestern Greece.
HIV/AIDS (Auckland, N.Z.) , 2015 | Pubmed ID: 26715861
Effect of dendritic cell state and antigen-presentation conditions on resulting T-cell phenotypes and Th cytokine profiles.
Immunobiology Aug, 2016 | Pubmed ID: 27130240
ERβ-Dependent Direct Suppression of Human and Murine Th17 Cells and Treatment of Established Central Nervous System Autoimmunity by a Neurosteroid.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2016 | Pubmed ID: 27549171
Regulatory Cell Populations in Relapsing-Remitting Multiple Sclerosis (RRMS) Patients: Effect of Disease Activity and Treatment Regimens.
International journal of molecular sciences Aug, 2016 | Pubmed ID: 27571060
Tregs and kidney: From diabetic nephropathy to renal transplantation.
World journal of transplantation Sep, 2016 | Pubmed ID: 27683634
Transcription Factor Ets-2 Acts as a Preinduction Repressor of Interleukin-2 (IL-2) Transcription in Naive T Helper Lymphocytes.
The Journal of biological chemistry Dec, 2016 | Pubmed ID: 27815505
Design and Synthesis of Non-Peptide Mimetics Mapping the Immunodominant Myelin Basic Protein (MBP) Epitope to Function as T-Cell Receptor Antagonists.
International journal of molecular sciences Jun, 2017 | Pubmed ID: 28594344
Bacterial load and cytokine profile in patients with cirrhosis following therapy with proton pump inhibitors: a prospective cohort study.
Annals of gastroenterology , 2017 | Pubmed ID: 28655984
Construction of an M1GS Ribozyme for Targeted and Rapid mRNA Cleavage; Application on the Ets-2 Oncogene.
Medicinal chemistry (Shariqah (United Arab Emirates)) , 2018 | Pubmed ID: 29332592
Ets-2 Acts As a Transcriptional Repressor of the Human Immunodeficiency Virus Type 1 through Binding to a Repressor-Activator Target Sequence of 5'-LTR.
Frontiers in immunology , 2017 | Pubmed ID: 29354130
Evaluation of T-lymphocyte subpopulations in actinic keratosis, in situ and invasive squamous cell carcinoma of the skin.
Journal of cutaneous pathology May, 2018 | Pubmed ID: 29419888
Clinical and immunological parameters of Sjögren's syndrome.
Autoimmunity reviews Oct, 2018 | Pubmed ID: 30103041
Prognostic significance of vitamin D receptor (VDR) gene polymorphisms in liver cirrhosis.
Scientific reports Sep, 2018 | Pubmed ID: 30218108
Metabolic Association between Leptin and the Corticotropin Releasing Hormone.
Endocrine, metabolic & immune disorders drug targets , 2019 | Pubmed ID: 30727936
The Prognostic Value of Endotoxemia and Intestinal Barrier Biomarker ZO-1 in Bacteremic Sepsis.
The American journal of the medical sciences Feb, 2020 | Pubmed ID: 31812215
Conditioning attenuates kidney and heart injury in rats following transient suprarenal occlusion of the abdominal aorta.
Scientific reports Mar, 2020 | Pubmed ID: 32193441
Fecal Microbiota Transplantation and Hydrocortisone Ameliorate Intestinal Barrier Dysfunction and Improve Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis.
Shock (Augusta, Ga.) May, 2021 | Pubmed ID: 32496421
Transcription factor Ets-2 regulates the expression of key lymphotropic factors.
Molecular biology reports Oct, 2020 | Pubmed ID: 33006713
Toward a new era of hepatitis B virus therapeutics: The pursuit of a functional cure.
World journal of gastroenterology Jun, 2021 | Pubmed ID: 34135551
The Influence of Nutritional Factors on Immunological Outcomes.
Frontiers in immunology , 2021 | Pubmed ID: 34135894
Intestinal Barrier Biomarker ZO1 and Endotoxin Are Increased in Blood of Patients With COVID-19-associated Pneumonia.
In vivo (Athens, Greece) , 2021 | Pubmed ID: 34182534
N-acetyl-cysteine reduces the risk for mechanical ventilation and mortality in patients with COVID-19 pneumonia: a two-center retrospective cohort study.
Infectious diseases (London, England) Nov, 2021 | Pubmed ID: 34182881
PD-L1 Expression, T-lymphocyte Subpopulations and Langerhans Cells in Cutaneous Squamous Cell Carcinoma and Precursor Lesions.
Anticancer research Jul, 2021 | Pubmed ID: 34230139
Synergistic effect of cold atmospheric pressure plasma and free or liposomal doxorubicin on melanoma cells.
Scientific reports Jul, 2021 | Pubmed ID: 34285268
The Role of Leptin in Childhood Immune Thrombocytopenia (ITP): An Anti-Inflammatory Agent?
International journal of molecular sciences Jul, 2021 | Pubmed ID: 34299256
Nucleic acid vaccines: A taboo broken and prospect for a hepatitis B virus cure.
World journal of gastroenterology Nov, 2021 | Pubmed ID: 34887624
Endotoxin Translocation and Gut Barrier Dysfunction Are Related to Variceal Bleeding in Patients With Liver Cirrhosis.
Frontiers in medicine , 2022 | Pubmed ID: 35308545
The role of vitamin D receptor polymorphisms in the course of chronic hepatitis C infection.
Annals of gastroenterology , 2022 | Pubmed ID: 35479594
Molecular basis of vitamin D action in inflammatory bowel disease.
Autoimmunity reviews Aug, 2022 | Pubmed ID: 35792343
Vitamin D-VDR Novel Anti-Inflammatory Molecules-New Insights into Their Effects on Liver Diseases.
International journal of molecular sciences Jul, 2022 | Pubmed ID: 35955597
Unveiling the biological role of sphingosine-1-phosphate receptor modulators in inflammatory bowel diseases.
World journal of gastroenterology Jan, 2023 | Pubmed ID: 36683721
Shifting gears: Study of immune system parameters of male habitual marathon runners.
Frontiers in immunology , 2022 | Pubmed ID: 36713459
miRNA Molecules-Late Breaking Treatment for Inflammatory Bowel Diseases?
International journal of molecular sciences Jan, 2023 | Pubmed ID: 36768556
Vitamin D and Microbiome: Molecular Interaction in Inflammatory Bowel Disease Pathogenesis.
The American journal of pathology Jun, 2023 | Pubmed ID: 36868465
Alterations in gut immunological barrier in SARS-CoV-2 infection and their prognostic potential.
Frontiers in immunology , 2023 | Pubmed ID: 37006316
Association of Antiretroviral Therapy with Platelet Function and Systemic Inflammatory Response in People Living with HIV: A Cross-Sectional Study.
Microorganisms Apr, 2023 | Pubmed ID: 37110381
Gene Polymorphisms and Biological Effects of Vitamin D Receptor on Nonalcoholic Fatty Liver Disease Development and Progression.
International journal of molecular sciences May, 2023 | Pubmed ID: 37175993
Creeping Fat in the Pathogenesis of Crohn's Disease: An Orchestrator or a Silent Bystander?
Inflammatory bowel diseases Jun, 2023 | Pubmed ID: 37260352
HIV-1 Transcriptional Activator Tat Inhibits Expression by Preventing the Presence of Pol II on the Promoter.
Biomolecules May, 2023 | Pubmed ID: 37371461
Exploring the Role of Vitamin D and the Vitamin D Receptor in the Composition of the Gut Microbiota.
Frontiers in bioscience (Landmark edition) Jun, 2023 | Pubmed ID: 37395032
Alexithymic characteristics and interoceptive abilities are associated with disease severity and levels of C-reactive protein and cytokines in patients with inflammatory bowel disease.
Annals of gastroenterology , 2023 | Pubmed ID: 37396003
Racheal Grace Akwii*,1,
Margarita Lamprou*,2,
Maria Georgomanoli3,
Andriana Plevriti2,
Antonia Marazioti4,
Athanasia Mouzaki5,
George Mattheolabakis6,
Constantinos M. Mikelis1,2
1Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center,
2Laboratory of Molecular Pharmacology, Department of Pharmacy, University of Patras,
3Division of Flow Cytometry and Division of MDx & Life Sciences, SB BioAnalytica,
4Basic Sciences Laboratory, Department of Physiotherapy, University of Peloponnese,
5Division of Hematology, Department of Internal Medicine, Medical School, University of Patras,
6School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe
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