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Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome and Posterior Probability of Mortality Benefit in a Post Hoc Bayesian Analysis of a Randomized Clinical Trial.
JAMA Dec, 2018 | Pubmed ID: 30347031
Diaphragmatic myotrauma: a mediator of prolonged ventilation and poor patient outcomes in acute respiratory failure.
The Lancet. Respiratory medicine Jan, 2019 | Pubmed ID: 30455078
Diaphragm-protective mechanical ventilation.
Current opinion in critical care Feb, 2019 | Pubmed ID: 30531536
Myotrauma in mechanically ventilated patients.
Intensive care medicine Jun, 2019 | Pubmed ID: 30741329
Withholding or withdrawing life support versus physician-assisted death: a distinction with a difference?
Current opinion in anaesthesiology Apr, 2019 | Pubmed ID: 30817393
Lung- and Diaphragm-protective Ventilation in Acute Respiratory Distress Syndrome: Rationale and Challenges.
Anesthesiology Apr, 2019 | Pubmed ID: 30844950
Optimal Ventilator Strategies in Acute Respiratory Distress Syndrome.
Seminars in respiratory and critical care medicine Feb, 2019 | Pubmed ID: 31060090
Determinants of the effect of extracorporeal carbon dioxide removal in the SUPERNOVA trial: implications for trial design.
Intensive care medicine Sep, 2019 | Pubmed ID: 31432216
Respiratory Drive in Critically Ill Patients. Pathophysiology and Clinical Implications.
American journal of respiratory and critical care medicine Jan, 2020 | Pubmed ID: 31437406
A novel non-invasive method to detect excessively high respiratory effort and dynamic transpulmonary driving pressure during mechanical ventilation.
Critical care (London, England) Nov, 2019 | Pubmed ID: 31694692
Editorial: Lung and diaphragm-protective ventilation: setting new concepts in historical context.
Current opinion in critical care Feb, 2020 | Pubmed ID: 31789946
Association of Low Baseline Diaphragm Muscle Mass With Prolonged Mechanical Ventilation and Mortality Among Critically Ill Adults.
JAMA network open Feb, 2020 | Pubmed ID: 32074293
Airway Occlusion Pressure As an Estimate of Respiratory Drive and Inspiratory Effort during Assisted Ventilation.
American journal of respiratory and critical care medicine May, 2020 | Pubmed ID: 32097569
Monitoring Patient Respiratory Effort During Mechanical Ventilation: Lung and Diaphragm-Protective Ventilation.
Critical care (London, England) Mar, 2020 | Pubmed ID: 32204729
Lung- and Diaphragm-Protective Ventilation.
American journal of respiratory and critical care medicine Oct, 2020 | Pubmed ID: 32516052
Monitoring patient-ventilator interaction by an end-expiratory occlusion maneuver.
Intensive care medicine Dec, 2020 | Pubmed ID: 32623476
Association of Mortality with Neuromuscular Blockade Differs according to Baseline Diaphragm Thickness.
American journal of respiratory and critical care medicine Dec, 2020 | Pubmed ID: 32717150
Anti-Thrombotic Therapy to Ameliorate Complications of COVID-19 (ATTACC): Study design and methodology for an international, adaptive Bayesian randomized controlled trial.
Clinical trials (London, England) Oct, 2020 | Pubmed ID: 32815416
Anticipating and managing coagulopathy and thrombotic manifestations of severe COVID-19.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne Oct, 2020 | Pubmed ID: 32816822
Comparing the Effects of Tidal Volume, Driving Pressure, and Mechanical Power on Mortality in Trials of Lung-Protective Mechanical Ventilation.
Respiratory care Feb, 2021 | Pubmed ID: 32843513
Effect of Driving Pressure Change During Extracorporeal Membrane Oxygenation in Adults With Acute Respiratory Distress Syndrome: A Randomized Crossover Physiologic Study.
Critical care medicine Dec, 2020 | Pubmed ID: 33044283
Validity of Empirical Estimates of the Ratio of Dead Space to Tidal Volume in ARDS.
Respiratory care Apr, 2021 | Pubmed ID: 33082218
Response to Ventilator Adjustments for Predicting Acute Respiratory Distress Syndrome Mortality. Driving Pressure versus Oxygenation.
Annals of the American Thoracic Society May, 2021 | Pubmed ID: 33112644
Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort.
Intensive care medicine Dec, 2020 | Pubmed ID: 33140181
Clinical trials in critical care: can a Bayesian approach enhance clinical and scientific decision making?
The Lancet. Respiratory medicine Feb, 2021 | Pubmed ID: 33227237
Is severe COVID-19 pneumonia a typical or atypical form of ARDS? And does it matter?
Intensive care medicine Jan, 2021 | Pubmed ID: 33237346
Searching for the Optimal PEEP in Patients Without ARDS: High, Low, or in Between?
JAMA Dec, 2020 | Pubmed ID: 33295963
A manifesto for the future of ICU trials.
Critical care (London, England) Dec, 2020 | Pubmed ID: 33298134
Duration of diaphragmatic inactivity after endotracheal intubation of critically ill patients.
Critical care (London, England) Jan, 2021 | Pubmed ID: 33430930
Association of Thoracic Computed Tomographic Measurements and Outcomes in Patients with Hematologic Malignancies Requiring Mechanical Ventilation.
Annals of the American Thoracic Society Jul, 2021 | Pubmed ID: 33433272
Effect of Lowering Vt on Mortality in Acute Respiratory Distress Syndrome Varies with Respiratory System Elastance.
American journal of respiratory and critical care medicine Jun, 2021 | Pubmed ID: 33439781
Diaphragm echodensity in mechanically ventilated patients: a description of technique and outcomes.
Critical care (London, England) Feb, 2021 | Pubmed ID: 33593412
Postextubation Respiratory Support: Of Clinical Trials and Clinical Decisions.
American journal of respiratory and critical care medicine Aug, 2021 | Pubmed ID: 33901412
Abdominal Muscle Use During Spontaneous Breathing and Cough in Patients Who Are Mechanically Ventilated: A Bi-center Ultrasound Study.
Chest Oct, 2021 | Pubmed ID: 34090872
How cutting-edge trial design can assess outcomes.
Current opinion in critical care Oct, 2021 | Pubmed ID: 34334624
Association of different positive end-expiratory pressure selection strategies with all-cause mortality in adult patients with acute respiratory distress syndrome.
Systematic reviews Aug, 2021 | Pubmed ID: 34384488
What Can We Learn From Monitoring Diaphragm Activity in Infants?
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies Nov, 2021 | Pubmed ID: 34734896
Noninvasive respiratory support following extubation in critically ill adults: a systematic review and network meta-analysis.
Intensive care medicine Feb, 2022 | Pubmed ID: 34825256
Impact of Reverse Triggering Dyssynchrony during Lung-Protective Ventilation on Diaphragm Function: An Experimental Model.
American journal of respiratory and critical care medicine Mar, 2022 | Pubmed ID: 34941477
Association of Positive End-Expiratory Pressure and Lung Recruitment Selection Strategies with Mortality in Acute Respiratory Distress Syndrome: A Systematic Review and Network Meta-analysis.
American journal of respiratory and critical care medicine Jun, 2022 | Pubmed ID: 35180042
Phrenic Nerve Block and Respiratory Effort in Pigs and Critically Ill Patients with Acute Lung Injury.
Anesthesiology May, 2022 | Pubmed ID: 35348581
EXpert consensus On Diaphragm UltraSonography in the critically ill (EXODUS): a Delphi consensus statement on the measurement of diaphragm ultrasound-derived parameters in a critical care setting.
Critical care (London, England) Apr, 2022 | Pubmed ID: 35395861
Physiology Is Vital to Precision Medicine in Acute Respiratory Distress Syndrome and Sepsis.
American journal of respiratory and critical care medicine Jul, 2022 | Pubmed ID: 35442864
Validation of a Web-based Platform for Online Training in Point-of-Care Diaphragm Ultrasound.
ATS scholar Mar, 2022 | Pubmed ID: 35633997
Phrenic nerve stimulation to protect the diaphragm, lung, and brain during mechanical ventilation.
Intensive care medicine Oct, 2022 | Pubmed ID: 35688993
Noninvasive and invasive mechanical ventilation for neurologic disorders.
Handbook of clinical neurology , 2022 | Pubmed ID: 36031314
Strategies for lung- and diaphragm-protective ventilation in acute hypoxemic respiratory failure: a physiological trial.
Critical care (London, England) Aug, 2022 | Pubmed ID: 36038890
A Window Into the Future: The Diagnostic and Prognostic Utility of Respiratory Muscle Ultrasound in Optimizing Mechanical Ventilation.
Respiratory care Nov, 2022 | Pubmed ID: 36266056
The religious character of secular arguments supporting euthanasia and what it implies for conscientious practice in medicine.
Theoretical medicine and bioethics Feb, 2023 | Pubmed ID: 36449202
Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study.
The Lancet. Respiratory medicine May, 2023 | Pubmed ID: 36693401
Linking Acute Physiology to Outcomes in the ICU: Challenges and Solutions for Research.
American journal of respiratory and critical care medicine Jun, 2023 | Pubmed ID: 36705985
Monitoring Respiratory Effort and Lung-distending Pressure Noninvasively during Mechanical Ventilation: Ready for Prime Time.
Anesthesiology Mar, 2023 | Pubmed ID: 36749421
Diaphragm Neurostimulation Assisted Ventilation in Critically Ill Patients.
American journal of respiratory and critical care medicine May, 2023 | Pubmed ID: 36917765
Association of Days Alive and at Home at Day 90 After Intensive Care Unit Admission With Long-term Survival and Functional Status Among Mechanically Ventilated Patients.
JAMA network open Mar, 2023 | Pubmed ID: 36929399
Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19.
JAMA Apr, 2023 | Pubmed ID: 36942550
Lung Recruitment Assessed by Electrical Impedance Tomography (RECRUIT): A Multicenter Study of COVID-19 Acute Respiratory Distress Syndrome.
American journal of respiratory and critical care medicine Jul, 2023 | Pubmed ID: 37097986
Reply to Fernández.
American journal of respiratory and critical care medicine Jul, 2023 | Pubmed ID: 37159944
Driving pressure: applying the concept at the bedside.
Intensive care medicine Aug, 2023 | Pubmed ID: 37191695
Bringing Clinical Trials to the Bedside: Conditional Average Treatment Effects in the Balanced Solution versus Saline in Intensive Care Study (BaSICS) Trial.
Annals of the American Thoracic Society Jun, 2023 | Pubmed ID: 37261790
Heterogeneous Treatment Effects of Extracorporeal CO Removal in Acute Hypoxemic Respiratory Failure.
American journal of respiratory and critical care medicine Sep, 2023 | Pubmed ID: 37433221
Driving pressure: pitfalls of methods that do not use esophageal pressure measurement. Author's reply.
Intensive care medicine Sep, 2023 | Pubmed ID: 37466671
Proof of Concept for Continuous On-Demand Phrenic Nerve Stimulation to Prevent Diaphragm Disuse during Mechanical Ventilation (STIMULUS): A Phase 1 Clinical Trial.
American journal of respiratory and critical care medicine Nov, 2023 | Pubmed ID: 37642635
Phrenic Nerve Stimulation for Acute Respiratory Failure.
Respiratory care Oct, 2023 | Pubmed ID: 37875317
Simvastatin in Critically Ill Patients with Covid-19.
The New England journal of medicine Oct, 2023 | Pubmed ID: 37888913
Lung and Diaphragm Protection During Mechanical Ventilation: Synchrony Matters.
Critical care medicine Nov, 2023 | Pubmed ID: 37902352
1, Toronto General Hospital Research Institute,
2Interdepartmental Division of Critical Care Medicine, University of Toronto,
3Department of Physiology, Faculty of Medicine, University of Toronto,
4Deparatment of Intensive Care Medicine, Nepean Hospital,
5Division of Respirology, Department of Medicine, University Health Network
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