Department of Pharmacology and Chemical Biology
Eric Erquan Zhang is a principal investigator at National Institute of Biological Sciences (NIBS), Beijing, China. He received his bachelor’s degree at East China Normal University, master’s degree at Fudan University in Shanghai, China, and Ph.D. from University of California San Diego, USA.
During his postdoctoral training with Dr. Steve Kay at The Scripps Research Institute and subsequently at University of California San Diego/Genomics Institute of the Novartis Research Foundation, Dr. Zhang conducted a whole genome siRNA screen and identified a couple of hundred human genes that impact the oscillation of the circadian clock, which governs our daily rhythms of behavior and metabolism. He also uncovered a genetic linkage between the liver clock and diabetes in mammals.
In 2011, Dr. Zhang was awarded by Chinese "Recruitment Program of Global Youth Experts" and became a faculty at NIBS, where he has worked ever since. The Zhang lab is interested in understanding all aspects of circadian rhythms: What is the clock? How does the clock run? Why is the clock relevant? In particular, the Zhang lab focuses on projects about dissecting the clock mechanism and highlighting its biological/biomedical significance in the scope of neuroscience and physiology.
Cyclase-associated protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase.
The Journal of biological chemistry May, 2018 | Pubmed ID: 29618512
CAP1 binds and activates adenylyl cyclase in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2021 | Pubmed ID: 34099549
Soluble cyclase-mediated nuclear cAMP synthesis is sufficient for cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2023 | Pubmed ID: 36656863
Performance Characteristics of Silicone Rubber for Use in Acidic Environments.
Polymers Aug, 2023 | Pubmed ID: 37688224
Comparison of invisalign mandibular advancement and twin-block on upper airway and hyoid bone position improvements for skeletal class II children: a retrospective study.
BMC oral health Sep, 2023 | Pubmed ID: 37705022
Ultrasensitive and selective detection of sulfamethazine in milk via a Janus-labeled Au nanoparticle-based surface-enhanced Raman scattering-immunochromatographic assay.
Talanta Jan, 2024 | Pubmed ID: 37717540
Acoustofluidics for simultaneous droplet transport and centrifugation facilitating ultrasensitive biomarker detection.
Lab on a chip Sep, 2023 | Pubmed ID: 37718921
Simultaneous Minimally Invasive Coronary Artery Bypass Grafting and Lung Resection.
The Thoracic and cardiovascular surgeon Nov, 2023 | Pubmed ID: 37774755
Outcomes of elderly peritoneal dialysis patients: 65-74 years old versus ≥ 75 years old.
Renal failure , 2023 | Pubmed ID: 37795800
Evaluation of the nutrition literacy assessment questionnaire for college students and identification of the influencing factors of their nutrition literacy.
BMC public health Oct, 2023 | Pubmed ID: 37904128
Optical detection using CRISPR-Cas12a of Helicobacter pylori for veterinary applications.
Mikrochimica acta Nov, 2023 | Pubmed ID: 37910191
Tetrandrine (TET) inhibits African swine fever virus entry into cells by blocking the PI3K/Akt pathway.
Virus research Jan, 2024 | Pubmed ID: 37923171
Single-Stage Surgical Procedure for Patients with Primary Esophageal and Lung Cancers.
The Thoracic and cardiovascular surgeon Dec, 2023 | Pubmed ID: 37935427
Impact of combining Lenvatinib with Transarterial chemoembolization for unresectable hepatocellular carcinoma.
Pakistan journal of medical sciences , 2023 | Pubmed ID: 37936761
Efficacy and safety comparison between Lenvatinib and Sorafenib in hepatocellular carcinoma treatment: a systematic review and meta-analysis of real-world study.
European journal of gastroenterology & hepatology Jan, 2024 | Pubmed ID: 37942731
Multi-omics analysis reveals the microbial interactions of S. cerevisiae and L. plantarum on Suanyu, Chinese traditional fermented fish.
Food research international (Ottawa, Ont.) Dec, 2023 | Pubmed ID: 37986426
First report of leaf spot disease caused by on Hua in Hunan Province of China.
Plant disease Nov, 2023 | Pubmed ID: 38037209
MicroRNA-146b negatively affects bovine embryo development and quality.
Reproduction (Cambridge, England) Dec, 2023 | Pubmed ID: 38063339
Prognostic significance of positive lymph node regression grade to neoadjuvant chemoradiation for esophageal squamous cell carcinoma.
Journal of surgical oncology Dec, 2023 | Pubmed ID: 38124398
Fully integrated wearable microneedle biosensing platform for wide-range and real-time continuous glucose monitoring.
Acta biomaterialia Feb, 2024 | Pubmed ID: 38160859
Synergism of fermented feed and ginseng polysaccharide on growth performance, intestinal development, and immunity of Xuefeng black-bone chickens.
BMC veterinary research Jan, 2024 | Pubmed ID: 38184589
The presence of intraductal carcinoma of prostate is a risk factor for poor pathologic response in men with high-risk prostate cancer receiving neoadjuvant therapy.
Urologic oncology Jan, 2024 | Pubmed ID: 38233262
Clinicopathologic features of a superficial CD34-positive fibroblastic tumor of the right hallux.
Asian journal of surgery Jan, 2024 | Pubmed ID: 38245423
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