Paul Kievit

Single-cell analysis of insulin-regulated fatty acid uptake in adipocytes.

Activity restriction, impaired capillary function, and the development of insulin resistance in lean primates.

Energizing the mind and body.

Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques.

Increased fibroblast growth factor 21 expression in high-fat diet-sensitive non-human primates (Macaca mulatta).

Leptin stimulates neuropeptide Y and cocaine amphetamine-regulated transcript coexpressing neuronal activity in the dorsomedial hypothalamus in diet-induced obese mice.

Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques.

Proinflammatory endothelial activation detected by molecular imaging in obese nonhuman primates coincides with onset of insulin resistance and progressively increases with duration of insulin resistance.

The nonhuman primate as a model for type 2 diabetes.

Preliminary Examination of Olanzapine and Diet Interactions On Metabolism in a Female Macaque.

Maternal high-fat diet and obesity impact palatable food intake and dopamine signaling in nonhuman primate offspring.

Temporal Changes in Skeletal Muscle Capillary Responses and Endothelial-Derived Vasodilators in Obesity-Related Insulin Resistance.

Vasoconstrictor eicosanoids and impaired microvascular function in inactive and insulin-resistant primates.

Perpetuating effects of androgen deficiency on insulin resistance.

Maternal and postnatal high-fat diet consumption programs energy balance and hypothalamic melanocortin signaling in nonhuman primate offspring.

Arcuate nucleus neuropeptide coexpression and connections to gonadotrophin-releasing hormone neurones in the female rhesus macaque.

Allogeneic stem cell transplantation in fully MHC-matched Mauritian cynomolgus macaques recapitulates diverse human clinical outcomes.

Use and Importance of Nonhuman Primates in Metabolic Disease Research: Current State of the Field.

Modulations in the offspring gut microbiome are refractory to postnatal synbiotic supplementation among juvenile primates.

Maternal Diet, Metabolic State, and Inflammatory Response Exert Unique and Long-Lasting Influences on Offspring Behavior in Non-Human Primates.

FGF21 decreases body weight without reducing food intake or bone mineral density in high-fat fed obese rhesus macaque monkeys.

Maternal High-Fat Diet Effects on Adaptations to Metabolic Challenges in Male and Female Juvenile Nonhuman Primates.

Early High-Fat Diet Exposure Causes Dysregulation of the Orexin and Dopamine Neuronal Populations in Nonhuman Primates.

Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates.

Estradiol Replacement Timing and Obesogenic Diet Effects on Body Composition and Metabolism in Postmenopausal Macaques.

A Long-Acting PYY Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates.

Early overnutrition alters synaptic signaling and induces leptin resistance in arcuate proopiomelanocortin neurons.

Maternal Western-style diet affects offspring islet composition and function in a non-human primate model of maternal over-nutrition.

Central and Peripheral Administration of Fibroblast Growth Factor 1 Improves Pancreatic Islet Insulin Secretion in Diabetic Mouse Models.

The development and ecology of the Japanese macaque gut microbiome from weaning to early adolescence in association with diet.

Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons.

Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates.

Effects of pre- and postnatal protein restriction on maternal and offspring metabolism in the nonhuman primate.

Maternal Obesity and Western-Style Diet Impair Fetal and Juvenile Offspring Skeletal Muscle Insulin-Stimulated Glucose Transport in Nonhuman Primates.

Palmitic Acid Targets Human Testicular Peritubular Cells and Causes a Pro-Inflammatory Response.

Leptin modulates pancreatic β-cell membrane potential through Src kinase-mediated phosphorylation of NMDA receptors.

Endocannabinoid Receptor-1 and Sympathetic Nervous System Mediate the Beneficial Metabolic Effects of Gastric Bypass.

Short-term Western-style diet negatively impacts reproductive outcomes in primates.

Arterial Platelet Adhesion in Atherosclerosis-Prone Arteries of Obese, Insulin-Resistant Nonhuman Primates.

Cross-species analysis defines the conservation of anatomically segregated VMH neuron populations.

Western-style diet consumption impairs maternal insulin sensitivity and glucose metabolism during pregnancy in a Japanese macaque model.

Maternal Western diet exposure increases periportal fibrosis beginning in utero in nonhuman primate offspring.

Fibroblast Growth Factor-1 Activates Neurons in the Arcuate Nucleus and Dorsal Vagal Complex.

Dipeptidyl peptidase IV inhibition delays developmental programming of obesity and metabolic disease in male offspring of obese mothers.

Bedding as an Enrichment Strategy in Group-housed Mauritian Cynomolgus Macaques ().

Ibrutinib Inhibits BMX-Dependent Endothelial VCAM-1 Expression and Pro-Atherosclerotic Endothelial Activation and Platelet Adhesion .

Effect of antiplatelet agents and tyrosine kinase inhibitors on oxLDL-mediated procoagulant platelet activity.

Maternal Western diet is associated with distinct preclinical pediatric NAFLD phenotypes in juvenile nonhuman primate offspring.

Glial, Neuronal, Vascular, Retinal Pigment Epithelium, and Inflammatory Cell Damage in a New Western Diet-Induced Primate Model of Diabetic Retinopathy.

Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring.

Maternal Western-style diet in nonhuman primates leads to offspring islet adaptations including altered gene expression and insulin hypersecretion.

Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques.

Metformin Disrupts Signaling and Metabolism in Fetal Hepatocytes.

Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models.

A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques.

Activation of coagulation FXI promotes endothelial inflammation and amplifies platelet activation in a nonhuman primate model of hyperlipidemia.

Initiation of metformin in early pregnancy results in fetal bioaccumulation, growth restriction, and renal dysmorphology in a primate model.

Analysis of beta-cell maturity and mitochondrial morphology in juvenile non-human primates exposed to maternal Western-style diet during development.

Effect of metabolic status on response to SIV infection and antiretroviral therapy in nonhuman primates.