Leonard J. Foster

A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling.

Mass spectrometric-based approaches in quantitative proteomics.

Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors.

Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins.

RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers.

Intracellular delivery of phosphatidylinositol (3,4,5)-trisphosphate causes incorporation of glucose transporter 4 into the plasma membrane of muscle and fat cells without increasing glucose uptake.

Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation.

Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).

Quantitative proteomic comparison of rat mitochondria from muscle, heart, and liver.

Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment.

A mammalian organelle map by protein correlation profiling.

Quantitative comparison of caste differences in honeybee hemolymph.

MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes.

PrestOMIC, an open source application for dissemination of proteomic datasets by individual laboratories.

Proteomics analysis of interleukin (IL)-7-induced signaling effectors shows selective changes in IL-7Ralpha449F knock-in T cell progenitors.

Lipid raft proteomics: more than just detergent-resistant membranes.

The dynamic phagosomal proteome and the contribution of the endoplasmic reticulum.

Proteomics of photoreceptor outer segments identifies a subset of SNARE and Rab proteins implicated in membrane vesicle trafficking and fusion.

Immunoproteomic discovery of novel T cell antigens from the obligate intracellular pathogen Chlamydia.

Proteomic analysis of the secretome of Leishmania donovani.

Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization.

Mapping the integrin-linked kinase interactome using SILAC.

Contributions of proteomics to understanding phagosome maturation.

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.

Identification of cognate host targets and specific ubiquitylation sites on the Salmonella SPI-1 effector SopB/SigD.

Identification and biochemical characterization of the SLC9A7 interactome.

Lessons learned from lipid raft proteomics.

Biochemical and proteomic approaches for the study of membrane microdomains.

Changes in protein expression during honey bee larval development.

Mitochondria do not contain lipid rafts, and lipid rafts do not contain mitochondrial proteins.

Moving closer to the lipid raft proteome using quantitative proteomics.

Cell-based identification of natural substrates and cleavage sites for extracellular proteases by SILAC proteomics.

Contributions of quantitative proteomics to understanding membrane microdomains.

Intracellular receptor for human host defense peptide LL-37 in monocytes.

The innate immune and systemic response in honey bees to a bacterial pathogen, Paenibacillus larvae.

Phosphoproteomics--finally fulfilling the promise?

Sequestosome-1/p62 is the key intracellular target of innate defense regulator peptide.

MSQuant, an open source platform for mass spectrometry-based quantitative proteomics.

A comprehensive proteomic analysis of the type III secretome of Citrobacter rodentium.

Quantitative analysis of proteome coverage and recovery rates for upstream fractionation methods in proteomics.

Structural and biochemical characterization of SrcA, a multi-cargo type III secretion chaperone in Salmonella required for pathogenic association with a host.

An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages.

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products.

The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling.

Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells.

PSORTb 3.0: improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes.

Release of membrane-bound vesicles and inhibition of tumor cell adhesion by the peptide Neopetrosiamide A.

Development of a Chlamydia trachomatis T cell Vaccine.

Ecological adaptation of diverse honey bee (Apis mellifera) populations.

An integrated global strategy for cell lysis, fractionation, enrichment and mass spectrometric analysis of phosphorylated peptides.

Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation.

EseG, an effector of the type III secretion system of Edwardsiella tarda, triggers microtubule destabilization.

Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells.

Trans-SILAC: sorting out the non-cell-autonomous proteome.

Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus.

Interpretation of data underlying the link between CCD and an invertebrate iridescent virus.

Immunization with live and dead Chlamydia muridarum induces different levels of protective immunity in a murine genital tract model: correlation with MHC class II peptide presentation and multifunctional Th1 cells.

Interpretation of data underlying the link between colony collapse disorder (CCD) and an invertebrate iridescent virus.

Organization and assembly of the TRAPPII complex.

Biomarkers for severity of spinal cord injury in the cerebrospinal fluid of rats.

Quantitative mass spectrometry catalogues Salmonella pathogenicity island-2 effectors and identifies their cognate host binding partners.

A honey bee (Apis mellifera L.) PeptideAtlas crossing castes and tissues.

Differential impact of caveolae and caveolin-1 scaffolds on the membrane raft proteome.

Quantitative proteomic analysis reveals formation of an EscL-EscQ-EscN type III complex in enteropathogenic Escherichia coli.

The pathogenic Escherichia coli type III secreted protease NleC degrades the host acetyltransferase p300.

Updated genome assembly and annotation of Paenibacillus larvae, the agent of American foulbrood disease of honey bees.

Phosphoproteomic analysis of Salmonella-infected cells identifies key kinase regulators and SopB-dependent host phosphorylation events.

The worker honeybee fat body proteome is extensively remodeled preceding a major life-history transition.

Expression of PTRF in PC-3 Cells Modulates Cholesterol Dynamics and the Actin Cytoskeleton Impacting Secretion Pathways.

Mechanisms of stable lipid loss in a social insect.

Cheminformatics-Driven Discovery of Selective, Nanomolar Inhibitors for Staphylococcal Pyruvate Kinase.

The gap junction protein Cx43 is involved in the bone-targeted metastatic behaviour of human prostate cancer cells.

Evaluation of mTOR-regulated mRNA translation.

Nanodiscs and SILAC-Based Mass Spectrometry to Identify a Membrane Protein Interactome.

Bromenshenk et al (PLoS One, 2011, 5(10):e13181) have claimed to have found peptides from an invertebrate iridovirus in bees.

Alternative reading frame selection mediated by a tRNA-like domain of an internal ribosome entry site.

Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis.