Bruce A. Molitoris

Gentamicin inhibits renal protein and phospholipid metabolism in rats: implications involving intracellular trafficking.

Ischemia induces alterations in actin filaments in renal vascular smooth muscle cells.

Endothelial injury and dysfunction in ischemic acute renal failure.

Functional studies of the kidney of living animals using multicolor two-photon microscopy.

Microvascular endothelial injury and dysfunction during ischemic acute renal failure.

Nucleotide depletion increases trafficking of gentamicin to the Golgi complex in LLC-PK1 cells.

Cardiovascular disease in patients with chronic kidney disease.

Transitioning to therapy in ischemic acute renal failure.

ADF/cofilin mediates actin cytoskeletal alterations in LLC-PK cells during ATP depletion.

A novel method to determine specificity and sensitivity of the TUNEL reaction in the quantitation of apoptosis.

Injury of the renal microvascular endothelium alters barrier function after ischemia.

Urinary actin, interleukin-6, and interleukin-8 may predict sustained ARF after ischemic injury in renal allografts.

Intravital imaging of the kidney using multiparameter multiphoton microscopy.

Newly developed techniques to study and diagnose acute renal failure.

Mechanism of actin polymerization in cellular ATP depletion.

Gentamicin traffics retrograde through the secretory pathway and is released in the cytosol via the endoplasmic reticulum.

Renal ischemia induces tropomyosin dissociation-destabilizing microvilli microfilaments.

Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy.

Endothelial injury and dysfunction: role in the extension phase of acute renal failure.

Actin cytoskeleton in ischemic acute renal failure.

Intravital multiphoton microscopy of dynamic renal processes.

Micropuncture gene delivery and intravital two-photon visualization of protein expression in rat kidney.

Quantitative intravital microscopy using a Generalized Polarity concept for kidney studies.

Renal blood flow in sepsis: a complex issue.

Adenoviral vectors expressing human endostatin-angiostatin and soluble Tie2: enhanced suppression of tumor growth and antiangiogenic effects in a prostate tumor model.

Cofilin mediates ATP depletion-induced endothelial cell actin alterations.

Loss of the homotypic fusion and vacuole protein sorting or golgi-associated retrograde protein vesicle tethering complexes results in gentamicin sensitivity in the yeast Saccharomyces cerevisiae.

Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001.

Advances in imaging the kidney and cellular processes.

Real-time studies of the progression of bacterial infections and immediate tissue responses in live animals.

A non-nephrotoxic gentamicin congener that retains antimicrobial efficacy.

Pharmacophotonics: utilizing multi-photon microscopy to quantify drug delivery and intracellular trafficking in the kidney.

Rapid determination of renal filtration function using an optical ratiometric imaging approach.

Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury.

Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2.

Quantifying dynamic kidney processes utilizing multi-photon microscopy.

Improving outcomes from acute kidney injury: report of an initiative.

Improving outcomes from acute kidney injury.

Improving outcomes of acute kidney injury: report of an initiative.

Progression of bacterial infections studied in real time--novel perspectives provided by multiphoton microscopy.

Improving outcomes from acute kidney injury: report of an initiative.

Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified Delphi process.

Technology Insight: biomarker development in acute kidney injury--what can we anticipate?

Quantifying endocytosis in vivo using intravital two-photon microscopy.

Bacterial infection-mediated mucosal signalling induces local renal ischaemia as a defence against sepsis.

Improvements in the diagnosis of acute kidney injury.

Contrast nephropathy: are short-term outcome measures adequate for quantification of long-term renal risk?

Imaging techniques in acute kidney injury.

Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1.

Acute kidney injury increases risk of ESRD among elderly.

Impaired tubular uptake explains albuminuria in early diabetic nephropathy.

Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activation.

Techniques to study nephron function: microscopy and imaging.

Soluble thrombomodulin protects ischemic kidneys.

Ironing out the pathogenesis of acute kidney injury.

Illuminating mitochondrial function and dysfunction using multiphoton technology.

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury.

Managing conflicts of interest: the road ahead.

ASN policy on managing conflicts of interest.

Activated protein C and acute kidney injury: Selective targeting of PAR-1.

Early monitoring of acute tubular necrosis in the rat kidney by 23Na-MRI.

Multiphoton imaging techniques in acute kidney injury.

Rapid diagnosis and quantification of acute kidney injury using fluorescent ratio-metric determination of glomerular filtration rate in the rat.

Intravital two-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models.

Lessons from Haiti on disaster relief.

The antibiotic gentamicin inhibits specific protein trafficking functions of the Arf1/2 family of GTPases.

Yet another advance in understanding albuminuria?

Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury.

Acute kidney injury in older adults.

Pathophysiology of ischemic acute kidney injury.

Uropathogenic Escherichia coli P and Type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction.

The future nephrology workforce: will there be one?

Implications of a nephrology workforce shortage for dialysis patient care.

Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact.

Circulating micro-RNAs in acute kidney injury: early observations.

Disease-specific kidney imaging: introduction.

A portable fiberoptic ratiometric fluorescence analyzer provides rapid point-of-care determination of glomerular filtration rate in large animals.

Kidney endothelial dysfunction: ischemia, localized infections and sepsis.

Multiple factors influence glomerular albumin permeability in rats.

Multiphoton microscopy applied for real-time intravital imaging of bacterial infections in vivo.

Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology.

Design of clinical trials in AKI: a report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings.

Designing clinical trials in acute kidney injury.

Design of clinical trials in acute kidney injury: a report from an NIDDK workshop--prevention trials.

A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney.

Chronic endothelin-1 infusion elevates glomerular sieving coefficient and proximal tubular albumin reuptake in the rat.

Toxicological and pharmacokinetic properties of chemically modified siRNAs targeting p53 RNA following intravenous administration.

In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury.

Measuring glomerular filtration rate in acute kidney injury: Yes, but not yet.

AKI is around the world but public recognition is lacking.

Measuring glomerular filtration rate in the intensive care unit: no substitutes please.

Screening: Screening for kidney disease--a lost opportunity.

The proximal tubule and albuminuria: really!

ASN Presidential Address 2013: innovation and individualization--the path forward for nephrology.

Letter to the editor: "Quantifying albumin permeability with multiphoton microscopy: why the difference?".

Therapeutic translation in acute kidney injury: the epithelial/endothelial axis.

Using 2-photon microscopy to understand albuminuria.

Dynamic multiphoton microscopy: focusing light on acute kidney injury.

Finding the bottom and using it: Offsets and sensitivity in the detection of low intensity values in vivo with 2-photon microscopy.

Urinary Biomarkers: Alone Are They Enough?

Shear stress is normalized in glomerular capillaries following ⅚ nephrectomy.

Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): a randomised clinical trial.

Renal endothelial injury and microvascular dysfunction in acute kidney injury.

Proximal Tubules Have the Capacity to Regulate Uptake of Albumin.

Nephrology research--the past, present and future.

Renal Hemodynamics in AKI: In Search of New Treatment Targets.

Mechanism of increased clearance of glycated albumin by proximal tubule cells.

Quantifying Glomerular Filtration Rates in Acute Kidney Injury: A Requirement for Translational Success.

Inhibition of v5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury.

Hydrodynamic Isotonic Fluid Delivery Ameliorates Moderate-to-Severe Ischemia-Reperfusion Injury in Rat Kidneys.

Rethinking CKD Evaluation: Should We Be Quantifying Basal or Stimulated GFR to Maximize Precision and Sensitivity?

Intravital Imaging of the Kidney in a Rat Model of Salt-Sensitive Hypertension.

Intravital multiphoton microscopy as a tool for studying renal physiology and pathophysiology.

Exogenous Gene Transmission of Isocitrate Dehydrogenase 2 Mimics Ischemic Preconditioning Protection.

Protective vascular coagulation in response to bacterial infection of the kidney is regulated by bacterial lipid A and host CD147.

A Novel Fluorescent Clinical Method to Rapidly Quantify Plasma Volume.

Beyond Biomarkers: Machine Learning in Diagnosing Acute Kidney Injury.

Fluorescent Imaging and Microscopy for Dynamic Processes in Rats.

Application of physiological shear stress to renal tubular epithelial cells.

DNA damage response protects against progressive kidney disease.

Kidney Mentoring and Assessment Program for Students: a guide for engaging medical students in nephrology.

Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine.

Conditional Myh9 and Myh10 inactivation in adult mouse renal epithelium results in progressive kidney disease.

Real-time glomerular filtration rate: improving sensitivity, accuracy and prognostic value in acute kidney injury.

Mechanism of how carbamylation reduces albumin binding to FcRn contributing to increased vascular clearance.

The Indiana O'Brien Center for Advanced Renal Microscopic Analysis.