Institute of Pharmacology
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Problem-based learning: a new pathway to competence?
Trends in pharmacological sciences Apr, 2002 | Pubmed ID: 11931987
Human inward rectifier potassium channels in chronic and postoperative atrial fibrillation.
Cardiovascular research May, 2002 | Pubmed ID: 12062344
What is a good tutorial from the student's point of view? Evaluation of tutorials in a newly established PBL block course "Basics of Drug Therapy".
Naunyn-Schmiedeberg's archives of pharmacology Jul, 2002 | Pubmed ID: 12107636
Rate-adaptive pacing using intracardiac impedance shows no evidence for positive feedback during dobutamine stress test.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Jul, 2002 | Pubmed ID: 12134978
Therapeutically relevant concentrations of neomycin selectively inhibit P-type Ca2+ channels in rat striatum.
European journal of pharmacology Feb, 2003 | Pubmed ID: 12586205
Cardiac sympathetic innervation and control of potassium channel function.
Journal of molecular and cellular cardiology Feb, 2003 | Pubmed ID: 12606253
Remodeling of cardiomyocyte ion channels in human atrial fibrillation.
Basic research in cardiology May, 2003 | Pubmed ID: 12883831
Transcription factors for ion channels: active or passive players in cardiac remodeling?
Cardiovascular research Nov, 2003 | Pubmed ID: 14613850
Decreased ATP-sensitive K(+) current density during chronic human atrial fibrillation.
Journal of molecular and cellular cardiology Dec, 2003 | Pubmed ID: 14654366
Mechanisms of beta-adrenergic receptor-mediated venodilation in humans.
Clinical pharmacology and therapeutics Jan, 2004 | Pubmed ID: 14749691
Muscarinic subtype-2 receptor autoantibodies: actors or bystanders in human atrial fibrillation?
European heart journal Jul, 2004 | Pubmed ID: 15231365
Role of IKur in controlling action potential shape and contractility in the human atrium: influence of chronic atrial fibrillation.
Circulation Oct, 2004 | Pubmed ID: 15477405
An aqueous extract of the marine sponge Ectyoplasia ferox stimulates L-type Ca2+-current by direct interaction with the Cav1.2 subunit.
Naunyn-Schmiedeberg's archives of pharmacology Dec, 2004 | Pubmed ID: 15599709
Recording atrial monophasic action potentials using standard pacemaker leads: an alternative way to study electrophysiology properties of the human atrium in vivo?
Pacing and clinical electrophysiology : PACE Dec, 2004 | Pubmed ID: 15613126
Defective cardiac ryanodine receptor regulation during atrial fibrillation.
Circulation Apr, 2005 | Pubmed ID: 15851612
Quantification of G protein Gaalphas subunit splice variants in different human tissues and cells using pyrosequencing.
Gene expression , 2005 | Pubmed ID: 15892449
Effects of immunoglobulin G from patients with dilated cardiomyopathy on rat cardiomyocytes.
Basic & clinical pharmacology & toxicology Jun, 2005 | Pubmed ID: 15910408
Comparing the global mRNA expression profile of human atrial and ventricular myocardium with high-density oligonucleotide arrays.
The Journal of thoracic and cardiovascular surgery Jun, 2005 | Pubmed ID: 15942582
Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation.
Circulation Jul, 2005 | Pubmed ID: 16027256
Electrical remodeling in atrial fibrillation.
Herz Apr, 2006 | Pubmed ID: 16738832
Do genetics help to better understand the underlying mechanisms of atrial fibrillation?
European heart journal Jul, 2006 | Pubmed ID: 16760202
Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes.
Biochemical and biophysical research communications Aug, 2006 | Pubmed ID: 16774736
Molecular determinants of altered Ca2+ handling in human chronic atrial fibrillation.
Circulation Aug, 2006 | Pubmed ID: 16894034
5-hydroxytryptamine and atrial arrhythmogenesis: a "culprit mechanism" or bystander in patients with chronic atrial fibrillation?
Journal of molecular and cellular cardiology Jan, 2007 | Pubmed ID: 17064728
Novel anti-arrhythmic agents for the treatment of atrial fibrillation.
Current opinion in pharmacology Apr, 2007 | Pubmed ID: 17303472
Differential phosphorylation-dependent regulation of constitutively active and muscarinic receptor-activated IK,ACh channels in patients with chronic atrial fibrillation.
Cardiovascular research Jun, 2007 | Pubmed ID: 17362895
Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure.
Journal of molecular and cellular cardiology Aug, 2007 | Pubmed ID: 17560599
Pharmacological evidence for altered src kinase regulation of I (Ca,L) in patients with chronic atrial fibrillation.
Naunyn-Schmiedeberg's archives of pharmacology Aug, 2007 | Pubmed ID: 17593353
Vascular large conductance calcium-activated potassium channels: functional role and therapeutic potential.
Naunyn-Schmiedeberg's archives of pharmacology Nov, 2007 | Pubmed ID: 17932654
Cardiomyocyte Ca2+ overload in atrial tachycardia: is blockade of L-type Ca2+ channels a promising approach to prevent electrical remodeling and arrhythmogenesis?
Naunyn-Schmiedeberg's archives of pharmacology Dec, 2007 | Pubmed ID: 17999053
Changes in I K, ACh single-channel activity with atrial tachycardia remodelling in canine atrial cardiomyocytes.
Cardiovascular research Jan, 2008 | Pubmed ID: 18006448
Bootstrapped two-electrode biosignal amplifier.
Medical & biological engineering & computing Jun, 2008 | Pubmed ID: 18266016
New concepts in understanding and modulating atrial repolarisation in patients with atrial fibrillation.
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing Aug, 2008 | Pubmed ID: 18330686
Four and a half LIM protein 1: a novel chaperone for atrium-specific Kv1.5 channels with a potential role in atrial arrhythmogenesis.
Cardiovascular research Jun, 2008 | Pubmed ID: 18390898
Digital lock-in techniques for adaptive power-line interference extraction.
Physiological measurement Jul, 2008 | Pubmed ID: 18560061
Intracellular calcium leak due to FKBP12.6 deficiency in mice facilitates the inducibility of atrial fibrillation.
Heart rhythm : the official journal of the Heart Rhythm Society Jul, 2008 | Pubmed ID: 18598963
Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy.
Cardiovascular research Dec, 2008 | Pubmed ID: 18689792
Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current.
Circulation research Oct, 2008 | Pubmed ID: 18723446
Calcium handling abnormalities in atrial fibrillation as a target for innovative therapeutics.
Journal of cardiovascular pharmacology Oct, 2008 | Pubmed ID: 18791467
Remodelling of cardiac repolarization: how homeostatic responses can lead to arrhythmogenesis.
Cardiovascular research Feb, 2009 | Pubmed ID: 18826964
Distinct contractile and molecular differences between two goat models of atrial dysfunction: AV block-induced atrial dilatation and atrial fibrillation.
Journal of molecular and cellular cardiology Mar, 2009 | Pubmed ID: 19100271
The German Competence Network on Atrial Fibrillation (AFNET).
Herz Dec, 2008 | Pubmed ID: 19137244
Acute atrial tachyarrhythmia induces angiotensin II type 1 receptor-mediated oxidative stress and microvascular flow abnormalities in the ventricles.
European heart journal Jun, 2009 | Pubmed ID: 19269986
Ion channel portrait of the human sinus node: useful for a better understanding of sinus node function and dysfunction in humans?
Circulation Mar, 2009 | Pubmed ID: 19332478
Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.
The Journal of clinical investigation Jul, 2009 | Pubmed ID: 19603549
Inhibition of IK,ACh current may contribute to clinical efficacy of class I and class III antiarrhythmic drugs in patients with atrial fibrillation.
Naunyn-Schmiedeberg's archives of pharmacology Mar, 2010 | Pubmed ID: 19760273
Atrial Ca2+ signaling in atrial fibrillation as an antiarrhythmic drug target.
Naunyn-Schmiedeberg's archives of pharmacology Mar, 2010 | Pubmed ID: 19784635
Atrial remodeling and atrial fibrillation: mechanisms and implications.
Circulation. Arrhythmia and electrophysiology Apr, 2008 | Pubmed ID: 19808395
Calcium-handling abnormalities underlying atrial arrhythmogenesis and contractile dysfunction in dogs with congestive heart failure.
Circulation. Arrhythmia and electrophysiology Jun, 2008 | Pubmed ID: 19808399
Animal models for atrial fibrillation: clinical insights and scientific opportunities.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Feb, 2010 | Pubmed ID: 19875395
Stroke prevention versus bleeding risk of vitamin-K antagonists: a double-edged sword in patients with atrial fibrillation who require surgery.
Cardiovascular therapeutics , 2009 | Pubmed ID: 19903184
Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging.
The Journal of clinical investigation Feb, 2010 | Pubmed ID: 20071777
New antiarrhythmic drugs for treatment of atrial fibrillation.
Lancet Apr, 2010 | Pubmed ID: 20334907
Aldosterone-receptor antagonism as a potential therapeutic option for atrial fibrillation.
British journal of pharmacology Apr, 2010 | Pubmed ID: 20388187
Left-to-right atrial inward rectifier potassium current gradients in patients with paroxysmal versus chronic atrial fibrillation.
Circulation. Arrhythmia and electrophysiology Oct, 2010 | Pubmed ID: 20657029
Multiple potential molecular contributors to atrial hypocontractility caused by atrial tachycardia remodeling in dogs.
Circulation. Arrhythmia and electrophysiology Oct, 2010 | Pubmed ID: 20660541
Calmodulin kinase II, sarcoplasmic reticulum Ca2+ leak, and atrial fibrillation.
Trends in cardiovascular medicine Jan, 2010 | Pubmed ID: 20685575
The impact of rapid atrial pacing on ADMA and endothelial NOS.
International journal of cardiology Jan, 2012 | Pubmed ID: 20926145
The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications.
Cardiovascular research Mar, 2011 | Pubmed ID: 20943673
Voltage-clamp-based methods for the detection of constitutively active acetylcholine-gated I(K,ACh) channels in the diseased heart.
Methods in enzymology , 2010 | Pubmed ID: 21036255
Vernakalant.
Nature reviews. Drug discovery Dec, 2010 | Pubmed ID: 21119728
Enhanced myofilament responsiveness upon β-adrenergic stimulation in post-infarct remodeled myocardium.
Journal of molecular and cellular cardiology Mar, 2011 | Pubmed ID: 21156182
Mechanisms of atrial tachyarrhythmias associated with coronary artery occlusion in a chronic canine model.
Circulation Jan, 2011 | Pubmed ID: 21200008
New insights into the molecular basis of atrial fibrillation: mechanistic and therapeutic implications.
Cardiovascular research Mar, 2011 | Pubmed ID: 21296897
Phosphatase-1 inhibitor-1 in physiological and pathological β-adrenoceptor signalling.
Cardiovascular research Aug, 2011 | Pubmed ID: 21354993
Atrial-selective sodium channel block by dronedarone: sufficient to terminate atrial fibrillation?
Naunyn-Schmiedeberg's archives of pharmacology Aug, 2011 | Pubmed ID: 21541758
Prevention of atrial fibrillation complications with antiarrhythmic drugs: still an unmet need in clinical practice.
Expert opinion on pharmacotherapy Jun, 2011 | Pubmed ID: 21548721
Ca(2+)-related signaling and protein phosphorylation abnormalities play central roles in a new experimental model of electrical storm.
Circulation May, 2011 | Pubmed ID: 21555709
No evidence for an association between the rs2824292 variant at chromosome 21q21 and ventricular fibrillation during acute myocardial infarction in a German population.
Clinical chemistry and laboratory medicine : CCLM / FESCC Jul, 2011 | Pubmed ID: 21574885
Role of T-type calcium channel subunits in post-myocardial infarction remodelling probed with genetically engineered mice.
Cardiovascular research Aug, 2011 | Pubmed ID: 21622683
Oxidized CaMKII causes cardiac sinus node dysfunction in mice.
The Journal of clinical investigation Aug, 2011 | Pubmed ID: 21785215
Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options--a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Jan, 2012 | Pubmed ID: 21791573
Recent advances in the molecular pathophysiology of atrial fibrillation.
The Journal of clinical investigation Aug, 2011 | Pubmed ID: 21804195
Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation.
Circulation Sep, 2011 | Pubmed ID: 21859974
Differential protein kinase C isoform regulation and increased constitutive activity of acetylcholine-regulated potassium channels in atrial remodeling.
Circulation research Oct, 2011 | Pubmed ID: 21903936
Human atrial action potential and Ca2+ model: sinus rhythm and chronic atrial fibrillation.
Circulation research Oct, 2011 | Pubmed ID: 21921263
Inhibition of CaMKII Phosphorylation of RyR2 Prevents Induction of Atrial Fibrillation in FKBP12.6 Knockout Mice.
Circulation research Feb, 2012 | Pubmed ID: 22158709
Proarrhythmic atrial calcium cycling in the diseased heart.
Advances in experimental medicine and biology , 2012 | Pubmed ID: 22453988
Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation.
Circulation May, 2012 | Pubmed ID: 22456474
Novel molecular targets for atrial fibrillation therapy.
Nature reviews. Drug discovery Apr, 2012 | Pubmed ID: 22460122
The multidimensional role of calcium in atrial fibrillation pathophysiology: mechanistic insights and therapeutic opportunities.
European heart journal Aug, 2012 | Pubmed ID: 22507975
Role of RyR2 phosphorylation at S2814 during heart failure progression.
Circulation research May, 2012 | Pubmed ID: 22511749
Calcium handling and atrial fibrillation.
Wiener medizinische Wochenschrift (1946) Jul, 2012 | Pubmed ID: 22695810
Systems approaches to post-operative atrial fibrillation - do they help us to better understand the ionic basis of the arrhythmogenic substrate?
Journal of molecular and cellular cardiology Sep, 2012 | Pubmed ID: 22742961
Is altered atrial microRNA-ome a critical contributor to the pathophysiology of atrial fibrillation?
Basic research in cardiology Sep, 2012 | Pubmed ID: 22802051
Palmitoylation and membrane association of the stress axis regulated insert (STREX) controls BK channel regulation by protein kinase C.
The Journal of biological chemistry Sep, 2012 | Pubmed ID: 22843729
Transient receptor potential canonical-3 channel-dependent fibroblast regulation in atrial fibrillation.
Circulation Oct, 2012 | Pubmed ID: 22992321
Voltage-gated Na⺠channels: novel players in fibroblast-to-myofibroblast transition with a potential role in atrial arrhythmogenesis?
The Journal of physiology Oct, 2012 | Pubmed ID: 23082023
Cellular and molecular correlates of ectopic activity in patients with atrial fibrillation.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Nov, 2012 | Pubmed ID: 23104921
The biology of human pulmonary veins: does it help us to better understand AF pathophysiology in patients?
Heart rhythm : the official journal of the Heart Rhythm Society Mar, 2013 | Pubmed ID: 23237913
New directions in antiarrhythmic drug therapy for atrial fibrillation.
Future cardiology Jan, 2013 | Pubmed ID: 23259476
Electrical storm: recent pathophysiological insights and therapeutic consequences.
Basic research in cardiology Mar, 2013 | Pubmed ID: 23429935
MicroRNA29: a mechanistic contributor and potential biomarker in atrial fibrillation.
Circulation Apr, 2013 | Pubmed ID: 23459615
Impaired Na(+)-dependent regulation of acetylcholine-activated inward-rectifier K(+) current modulates action potential rate dependence in patients with chronic atrial fibrillation.
Journal of molecular and cellular cardiology Mar, 2013 | Pubmed ID: 23531443
Pleiotropic actions of amiodarone: still puzzling after half a century.
Naunyn-Schmiedeberg's archives of pharmacology Jul, 2013 | Pubmed ID: 23568552
Atrial fibrillation promotion by endurance exercise: demonstration and mechanistic exploration in an animal model.
Journal of the American College of Cardiology Jul, 2013 | Pubmed ID: 23583240
KCNQ1 autoantibodies: another way to regulate IKs.
Cardiovascular research Jun, 2013 | Pubmed ID: 23615563
Safety and efficacy of vernakalant for acute cardioversion of atrial fibrillation: an update.
Vascular health and risk management , 2013 | Pubmed ID: 23637539
Phosphodiesterase-2 is Upregulated in Human Failing Hearts and Blunts β-Adrenergic Responses in Cardiomyocytes.
Journal of the American College of Cardiology Jun, 2013 | Pubmed ID: 23810893
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