Anne Gershenson

Post-reductionist protein science, or putting Humpty Dumpty back together again.

Protein folding in the cell: challenges and progress.

Determining serpin conformational distributions with single molecule fluorescence.

Competition between anion binding and dimerization modulates Staphylococcus aureus phosphatidylinositol-specific phospholipase C enzymatic activity.

Does changing the predicted dynamics of a phospholipase C alter activity and membrane binding?

Cation-π interactions as lipid-specific anchors for phosphatidylinositol-specific phospholipase C.

The cation-π box is a specific phosphatidylcholine membrane targeting motif.

Deciphering protein stability in cells.

Collapse of a long axis: single-molecule Förster resonance energy transfer and serpin equilibrium unfolding.

Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs).

Serpin latency transition at atomic resolution.

Energy landscapes of functional proteins are inherently risky.

Quantifying transient interactions between Bacillus phosphatidylinositol-specific phospholipase-C and phosphatidylcholine-rich vesicles.

Fluorinated Aromatic Amino Acids Distinguish Cation-π Interactions from Membrane Insertion.

Interactions of Haptoglobin with Monomeric Globin Species: Insights from Molecular Modeling and Native Electrospray Ionization Mass Spectrometry.

Recombinant broad-range phospholipase C from Listeria monocytogenes exhibits optimal activity at acidic pH.

A Role for Weak Electrostatic Interactions in Peripheral Membrane Protein Binding.

Cellular folding pathway of a metastable serpin.

Expression and Purification of Active Recombinant Human Alpha-1 Antitrypsin (AAT) from Escherichia coli.

The binding of activated Gα to phospholipase C-β exhibits anomalous affinity.

All-Atom Simulations Reveal How Single-Point Mutations Promote Serpin Misfolding.

Search and Subvert: Minimalist Bacterial Phosphatidylinositol-Specific Phospholipase C Enzymes.

Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription.

Interfacial Aromatics Mediating Cation-π Interactions with Choline-Containing Lipids Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted below the Phosphates.

Proper secretion of the serpin antithrombin relies strictly on thiol-dependent quality control.

Successes and challenges in simulating the folding of large proteins.

Implementing In-Cell Fast Photochemical Oxidation of Proteins in a Platform Incubator with a Movable XY Stage.

Heterogeneous Diffusion of Polystyrene Nanoparticles through an Alginate Matrix: The Role of Cross-linking and Particle Size.