Edouard G. Stanley

Bone morphogenetic proteins promote development of fetal pancreas epithelial colonies containing insulin-positive cells.

Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo.

Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3'UTR-ires-Cre allele of the homeobox gene Nkx2-5.

Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation.

SOCS3 negatively regulates IL-6 signaling in vivo.

Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1.

Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death.

Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin.

Characterization of mice lacking the tetraspanin superfamily member CD151.

Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells.

The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells.

The hESC line Envy expresses high levels of GFP in all differentiated progeny.

Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation.

Mixl1 and oct4 proteins are transiently co-expressed in differentiating mouse and human embryonic stem cells.

Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene.

A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function.

A method for genetic modification of human embryonic stem cells using electroporation.

Hrk/DP5 contributes to the apoptosis of select neuronal populations but is dispensable for haematopoietic cell apoptosis.

Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis.

Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors.

Building better beta cells.

A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies.

Expansion of human embryonic stem cells in vitro.

Directed differentiation of human embryonic stem cells as spin embryoid bodies and a description of the hematopoietic blast colony forming assay.

Pancreas differentiation of mouse ES cells.

A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis.

Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation.

Pancreatic differentiation from pluripotent stem cells: tweaking the system.

Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid.

Stems cells and the price of immortality.

ErythRED, a hESC line enabling identification of erythroid cells.

Reshaping pluripotent stem cells.

Generation of human embryonic stem cell reporter knock-in lines by homologous recombination.

Fourier transform infrared microspectroscopy identifies early lineage commitment in differentiating human embryonic stem cells.

Differentiating embryonic stem cells pass through 'temporal windows' that mark responsiveness to exogenous and paracrine mesendoderm inducing signals.

Expression from a betageo gene trap in the Slain1 gene locus is predominantly associated with the developing nervous system.

Defined substrates for pluripotent stem cells: are we there yet?

Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.

A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives.

Generation of human female reproductive tract epithelium from human embryonic stem cells.

NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.

SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells.

Temporal restriction of pancreatic branching competence during embryogenesis is mirrored in differentiating embryonic stem cells.

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity.

Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells.

Generating GABAergic cerebral cortical interneurons from mouse and human embryonic stem cells.

Efficient generation of adipocytes in a dish.

The Mix family of homeobox genes--key regulators of mesendoderm formation during vertebrate development.

APELIN promotes hematopoiesis from human embryonic stem cells.

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization.

Analysis of mitochondrial function and localisation during human embryonic stem cell differentiation in vitro.

Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation.

Human embryonic stem cell derived mesenchymal progenitors express cardiac markers but do not form contractile cardiomyocytes.

Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.

Fourier transform infrared microspectroscopy reveals unique phenotypes for human embryonic and induced pluripotent stem cell lines and their progeny.

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells.

Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

Fourier transform infrared microspectroscopy reveals that tissue culture conditions affect the macromolecular phenotype of human embryonic stem cells.

Rewiring immunity: generating a functional thymus from hESCs… are we there yet?

WNT3A promotes hematopoietic or mesenchymal differentiation from hESCs depending on the time of exposure.

The characterisation of pluripotent and multipotent stem cells using Fourier transform infrared microspectroscopy.

Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations.

FOXN1 (GFP/w) reporter hESCs enable identification of integrin-β4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1(+) thymic epithelial progenitors.

SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development.

Derivation of insulin-producing beta-cells from human pluripotent stem cells.

β-cell regeneration and differentiation: how close are we to the 'holy grail'?

Efficient Generation of NKX6-1(+) Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines.

Productive Infection of Human Embryonic Stem Cell-Derived NKX2.1+ Respiratory Progenitors With Human Rhinovirus.

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages.