Institute for Ophthalmic Research
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Turning teratocarcinoma cells into neurons: rapid differentiation of NT-2 cells in floating spheres.
Brain research. Developmental brain research May, 2003 | Pubmed ID: 12711367
Hypoxic/ischaemic cell damage in cultured human NT-2 neurons.
Brain research Jun, 2004 | Pubmed ID: 15140642
Differential modification of phosducin protein in degenerating rd1 retina is associated with constitutively active Ca2+/calmodulin kinase II in rod outer segments.
Molecular & cellular proteomics : MCP Feb, 2006 | Pubmed ID: 16253986
Calpain is activated in degenerating photoreceptors in the rd1 mouse.
Journal of neurochemistry Feb, 2006 | Pubmed ID: 16405498
Up-regulation and increased phosphorylation of protein kinase C (PKC) delta, mu and theta in the degenerating rd1 mouse retina.
Molecular and cellular neurosciences Apr, 2006 | Pubmed ID: 16503160
Diltiazem protects human NT-2 neurons against excitotoxic damage in a model of simulated ischemia.
Brain research Dec, 2006 | Pubmed ID: 17070504
CNTF+BDNF treatment and neuroprotective pathways in the rd1 mouse retina.
Brain research Jan, 2007 | Pubmed ID: 17156753
Calpain activity in retinal degeneration.
Journal of neuroscience research Mar, 2007 | Pubmed ID: 17171699
Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2007 | Pubmed ID: 17881537
Human model neurons in studies of brain cell damage and neural repair.
Current molecular medicine Sep, 2007 | Pubmed ID: 17896991
Photoreceptor cell death mechanisms in inherited retinal degeneration.
Molecular neurobiology Dec, 2008 | Pubmed ID: 18982459
PKG activity causes photoreceptor cell death in two retinitis pigmentosa models.
Journal of neurochemistry Feb, 2009 | Pubmed ID: 19187097
Cellular phenotypes of human model neurons (NT2) after differentiation in aggregate culture.
Cell and tissue research Jun, 2009 | Pubmed ID: 19377856
Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP).
Investigative ophthalmology & visual science Dec, 2009 | Pubmed ID: 19578015
Spectral domain optical coherence tomography in mouse models of retinal degeneration.
Investigative ophthalmology & visual science Dec, 2009 | Pubmed ID: 19661229
Simulation of stroke-related damage in cultured human nerve cells.
ALTEX , 2007 | Pubmed ID: 19835047
cGMP-dependent cone photoreceptor degeneration in the cpfl1 mouse retina.
The Journal of comparative neurology Sep, 2010 | Pubmed ID: 20593360
Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2010 | Pubmed ID: 20628362
Photoreceptor rescue and toxicity induced by different calpain inhibitors.
Journal of neurochemistry Nov, 2010 | Pubmed ID: 20807308
PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function.
PloS one , 2010 | Pubmed ID: 21124852
A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa.
Human molecular genetics Mar, 2011 | Pubmed ID: 21149284
Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats.
PloS one , 2011 | Pubmed ID: 21765948
HDAC inhibition prevents Rd1 mouse photoreceptor degeneration.
Advances in experimental medicine and biology , 2012 | Pubmed ID: 22183322
In vivo assessment of rodent retinal structure using spectral domain optical coherence tomography.
Advances in experimental medicine and biology , 2012 | Pubmed ID: 22183368
cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function.
Nature medicine Feb, 2012 | Pubmed ID: 22270721
Light-driven calcium signals in mouse cone photoreceptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2012 | Pubmed ID: 22593066
Calpain mediated ataxin-3 cleavage in the molecular pathogenesis of Spinocerebellar Ataxia Type 3 (SCA3).
Human molecular genetics Oct, 2012 | Pubmed ID: 23100324
Testing for a gap junction-mediated bystander effect in retinitis pigmentosa: secondary cone death is not altered by deletion of connexin36 from cones.
PloS one , 2013 | Pubmed ID: 23468924
Retinitis Pigmentosa: over-expression of anti-ageing protein Klotho in degenerating photoreceptors.
Journal of neurochemistry Dec, 2013 | Pubmed ID: 23796581
Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina.
The Journal of biological chemistry Dec, 2013 | Pubmed ID: 24187136
Expression of poly(ADP-ribose) glycohydrolase in wild-type and PARG-110 knock-out retina.
Advances in experimental medicine and biology , 2014 | Pubmed ID: 24664732
Characterization of a mouse model with complete RPE loss and its use for RPE cell transplantation.
Investigative ophthalmology & visual science Aug, 2014 | Pubmed ID: 25103259
Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration.
PloS one , 2014 | Pubmed ID: 25392995
Targeted Ablation of the Pde6h Gene in Mice Reveals Cross-species Differences in Cone and Rod Phototransduction Protein Isoform Inventory.
The Journal of biological chemistry Apr, 2015 | Pubmed ID: 25739440
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