Heather R. Christofk

New aspects of the Warburg effect in cancer cell biology.

Histone acetylation regulates intracellular pH.

Metabolomics strategy reveals subpopulation of liposarcomas sensitive to gemcitabine treatment.

Novel dedifferentiated liposarcoma xenograft models reveal PTEN down-regulation as a malignant signature and response to PI3K pathway inhibition.

An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity.

EGFR Mutation-Induced Alternative Splicing of Max Contributes to Growth of Glycolytic Tumors in Brain Cancer.

Doxycycline alters metabolism and proliferation of human cell lines.

Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication.

The metabolic milieu of metastases.

2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling.

MYC-induced reprogramming of glutamine catabolism supports optimal virus replication.

MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.

Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.

Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State.

Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer.

Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures.

mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT.

The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma.