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Sara M. Lopes

CNC-UC - Center for Neuroscience and Cell Biology,
CIBB - Center for Innovative Biomedicine and Biotechnology,
IIIUC - Institute for Interdisciplinary Research

University of Coimbra

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PUBLICATIONS

Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders.

Brain : a journal of neurology Feb, 2020 | Pubmed ID: 31738395

Protocol for the Characterization of the Cytosine-Adenine-Guanine Tract and Flanking Polymorphisms in Machado-Joseph Disease: Impact on Diagnosis and Development of Gene-Based Therapies.

The Journal of molecular diagnostics : JMD Jun, 2020 | Pubmed ID: 32205289

ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease.

Molecular therapy : the journal of the American Society of Gene Therapy Jan, 2022 | Pubmed ID: 34298131

miRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3.

Nucleic acid therapeutics Jun, 2022 | Pubmed ID: 34878314

A new protocol for whole-brain biodistribution analysis of AAVs by tissue clearing, light-sheet microscopy and semi-automated spatial quantification.

Gene therapy Dec, 2022 | Pubmed ID: 36316447

INSTITUTIONS

University of Coimbra

JOVE ARTICLES

Isolation of Adeno-Associated Viral Vectors Through a Single-Step and Semi-Automated Heparin Affinity Chromatography Protocol

Miguel M. Lopes^*,1,2,3,

Sara M. Lopes^*,1,2,3,

Rafael Baganha^1,2,4,

Carina Henriques^1,2,5,

Ana C. Silva^1,2,3,

Diana D. Lobo^1,2,3,

Luísa Cortes^1,2,3,6,

Luís Pereira de Almeida^*,1,2,4,5,

Rui Jorge Nobre^*,1,2,3,4

¹CNC-UC - Center for Neuroscience and Cell Biology, University of Coimbra,

²CIBB - Center for Innovative Biomedicine and Biotechnology, University of Coimbra,

³IIIUC - Institute for Interdisciplinary Research, University of Coimbra,

⁴ViraVector - Viral Vectors for Gene Transfer Core Facility, University of Coimbra,

⁵FFUC - Faculty of Pharmacy, University of Coimbra,

⁶MICC-CNC - Microscopy Imaging Center of Coimbra - CNC, University of Coimbra

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Sara M. Lopes

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}CNC-UC - Center for Neuroscience and Cell Biology,CIBB - Center for Innovative Biomedicine and Biotechnology,IIIUC - Institute for Interdisciplinary Research

University of Coimbra

Isolation of Adeno-Associated Viral Vectors Through a Single-Step and Semi-Automated Heparin Affinity Chromatography Protocol

CNC-UC - Center for Neuroscience and Cell Biology,
CIBB - Center for Innovative Biomedicine and Biotechnology,
IIIUC - Institute for Interdisciplinary Research