Centre for integrative Physiology
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Age-dependent synapse withdrawal at axotomised neuromuscular junctions in Wld(s) mutant and Ube4b/Nmnat transgenic mice.
The Journal of physiology Sep, 2002 | Pubmed ID: 12231635
Ultrastructural correlates of synapse withdrawal at axotomized neuromuscular junctions in mutant and transgenic mice expressing the Wld gene.
Journal of anatomy Sep, 2003 | Pubmed ID: 14529044
Neuroprotection after transient global cerebral ischemia in Wld(s) mutant mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Jan, 2004 | Pubmed ID: 14688617
The relationship of neuromuscular synapse elimination to synaptic degeneration and pathology: insights from WldS and other mutant mice.
Journal of neurocytology Jun-Sep, 2003 | Pubmed ID: 15034273
Axotomy-dependent and -independent synapse elimination in organ cultures of Wld(s) mutant mouse skeletal muscle.
Journal of neuroscience research Apr, 2004 | Pubmed ID: 15048930
Myo-GDNF increases non-functional polyinnervation of reinnervated mouse muscle.
Neuroreport Jan, 2004 | Pubmed ID: 15106825
Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation.
The European journal of neuroscience Dec, 2004 | Pubmed ID: 15579164
The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice.
Brain : a journal of neurology Feb, 2005 | Pubmed ID: 15644421
A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses.
The European journal of neuroscience Jan, 2005 | Pubmed ID: 15654865
Progressive loss of motor neuron function in wasted mice: effects of a spontaneous null mutation in the gene for the eEF1 A2 translation factor.
Journal of neuropathology and experimental neurology Apr, 2005 | Pubmed ID: 15835265
The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells.
Human molecular genetics Feb, 2006 | Pubmed ID: 16403805
Synaptic Ras GTPase activating protein regulates pattern formation in the trigeminal system of mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2006 | Pubmed ID: 16452659
Involvement of protein kinase A in patterning of the mouse somatosensory cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2006 | Pubmed ID: 16707791
Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion.
Brain : a journal of neurology Jun, 2006 | Pubmed ID: 16738060
Synaptic vulnerability in neurodegenerative disease.
Journal of neuropathology and experimental neurology Aug, 2006 | Pubmed ID: 16896307
Differential proteomics analysis of synaptic proteins identifies potential cellular targets and protein mediators of synaptic neuroprotection conferred by the slow Wallerian degeneration (Wlds) gene.
Molecular & cellular proteomics : MCP Aug, 2007 | Pubmed ID: 17470424
Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene.
Molecular neurodegeneration , 2007 | Pubmed ID: 17971231
Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy.
Human molecular genetics Apr, 2008 | Pubmed ID: 18065780
Synaptic changes in the thalamocortical system of cathepsin D-deficient mice: a model of human congenital neuronal ceroid-lipofuscinosis.
Journal of neuropathology and experimental neurology Jan, 2008 | Pubmed ID: 18091563
A neurological phenotype in mice with DNA repair gene Ercc1 deficiency.
DNA repair Feb, 2008 | Pubmed ID: 18221731
VAPB interacts with and modulates the activity of ATF6.
Human molecular genetics Jun, 2008 | Pubmed ID: 18263603
VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S).
Molecular and cellular neurosciences Jul, 2008 | Pubmed ID: 18468455
Rapid loss of motor nerve terminals following hypoxia-reperfusion injury occurs via mechanisms distinct from classic Wallerian degeneration.
Journal of anatomy Jun, 2008 | Pubmed ID: 18510509
Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds).
Genome biology , 2008 | Pubmed ID: 18570652
Identity, developmental restriction and reactivity of extralaminar cells capping mammalian neuromuscular junctions.
Journal of cell science Dec, 2008 | Pubmed ID: 19001504
mGluR5 regulates glutamate-dependent development of the mouse somatosensory cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2008 | Pubmed ID: 19052194
Loss of translation elongation factor (eEF1A2) expression in vivo differentiates between Wallerian degeneration and dying-back neuronal pathology.
Journal of anatomy Dec, 2008 | Pubmed ID: 19094180
The importance of exposure to human material in anatomical education: a philosophical perspective.
Anatomical sciences education Nov-Dec, 2008 | Pubmed ID: 19109856
Protein product of CLN6 gene responsible for variant late-onset infantile neuronal ceroid lipofuscinosis interacts with CRMP-2.
Journal of neuroscience research Jul, 2009 | Pubmed ID: 19235893
Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin.
Molecules and cells Mar, 2009 | Pubmed ID: 19326073
Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease.
Human molecular genetics Nov, 2009 | Pubmed ID: 19640925
Murine cathepsin D deficiency is associated with dysmyelination/myelin disruption and accumulation of cholesteryl esters in the brain.
Journal of neurochemistry Jan, 2010 | Pubmed ID: 19845830
Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy.
Human molecular genetics Feb, 2010 | Pubmed ID: 19884170
Expression of the neuroprotective slow Wallerian degeneration (WldS) gene in non-neuronal tissues.
BMC neuroscience , 2009 | Pubmed ID: 20015399
Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy.
PLoS genetics Dec, 2009 | Pubmed ID: 20019802
Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice.
Acta neuropathologica Oct, 2010 | Pubmed ID: 20602234
SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy.
Human molecular genetics Nov, 2010 | Pubmed ID: 20705736
Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose.
PloS one , 2010 | Pubmed ID: 21124744
The response of neuromuscular junctions to injury is developmentally regulated.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Apr, 2011 | Pubmed ID: 21228222
Induction of cell stress in neurons from transgenic mice expressing yellow fluorescent protein: implications for neurodegeneration research.
PloS one , 2011 | Pubmed ID: 21408118
ApoE isoform-specific regulation of regeneration in the peripheral nervous system.
Human molecular genetics Jun, 2011 | Pubmed ID: 21478199
The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy.
Disease models & mechanisms Jul, 2011 | Pubmed ID: 21708901
Targeting synaptic pathology in multiple sclerosis: fingolimod to the rescue?
British journal of pharmacology Feb, 2012 | Pubmed ID: 21806598
Reversible molecular pathology of skeletal muscle in spinal muscular atrophy.
Human molecular genetics Nov, 2011 | Pubmed ID: 21840928
Morphologic and functional correlates of synaptic pathology in the cathepsin D knockout mouse model of congenital neuronal ceroid lipofuscinosis.
Journal of neuropathology and experimental neurology Dec, 2011 | Pubmed ID: 22082660
Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality?
Journal of anatomy Feb, 2012 | Pubmed ID: 22133357
Development of a supported self-directed learning approach for anatomy education.
Anatomical sciences education Mar-Apr, 2012 | Pubmed ID: 22223487
Altered maturation of the primary somatosensory cortex in a mouse model of fragile X syndrome.
Human molecular genetics May, 2012 | Pubmed ID: 22328088
WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering.
Current biology : CB Apr, 2012 | Pubmed ID: 22425157
Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo.
PLoS genetics , 2012 | Pubmed ID: 22952455
Spinal muscular atrophy: going beyond the motor neuron.
Trends in molecular medicine Jan, 2013 | Pubmed ID: 23228902
Morphological characteristics of motor neurons do not determine their relative susceptibility to degeneration in a mouse model of severe spinal muscular atrophy.
PloS one , 2012 | Pubmed ID: 23285108
Quantitative tractography and tract shape modeling in amyotrophic lateral sclerosis.
Journal of magnetic resonance imaging : JMRI Nov, 2013 | Pubmed ID: 23450730
Effect of limb lengthening on internodal length and conduction velocity of peripheral nerve.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2013 | Pubmed ID: 23467369
Increasing SMN levels using the histone deacetylase inhibitor SAHA ameliorates defects in skeletal muscle microvasculature in a mouse model of severe spinal muscular atrophy.
Neuroscience letters Jun, 2013 | Pubmed ID: 23583590
Studying synapses in human brain with array tomography and electron microscopy.
Nature protocols , 2013 | Pubmed ID: 23787894
Total protein analysis as a reliable loading control for quantitative fluorescent Western blotting.
PloS one , 2013 | Pubmed ID: 24023619
Executive deficits, not processing speed relates to abnormalities in distinct prefrontal tracts in amyotrophic lateral sclerosis.
Brain : a journal of neurology Nov, 2013 | Pubmed ID: 24056536
Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy.
Genome medicine Oct, 2013 | Pubmed ID: 24134804
SMN-dependent intrinsic defects in Schwann cells in mouse models of spinal muscular atrophy.
Human molecular genetics Dec, 2013 | Pubmed ID: 24301677
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