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Peking University School and Hospital of Stomatology

2 ARTICLES PUBLISHED IN JoVE

Medicine

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Xinjia Cai^1,2, Heyu Zhang³, Jianyun Zhang^1,2, Tiejun Li^1,2

¹Department of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, ²Research Unit of Precision Pathologic Diagnosis in Tumors of the Oral and Maxillofacial Regions, Chinese Academy of Medical Sciences (2019RU034), ³Central Laboratory, Peking University School and Hospital of Stomatology

Laser capture microdissection of oral submucous fibrosis tissues allows for precise extraction of cells from histological regions of interest for the analysis of multi-omics data with morphological and spatial information.

Medicine

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Xiaoyan Wang^1,2,3, Yeqing Song⁴, Xinzhe Lou¹, Bingqing Han^5,6,7, Ruiqing Wu¹, Jing Xie^8,9, Xiang Lin^8,9, Hao Wang¹

¹Department of Stomatology, Beijing Tiantan Hospital, Capital Medical University, ²Beijing Laboratory of Oral Health, Capital Medical University, ³Department of Biochemistry and Molecular Biology, School of Basic Medicine, Capital Medical University, ⁴Central Laboratory, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, ⁵Clinical Diagnosis Laboratory of Beijing Tiantan Hospital, Capital Medical University, ⁶Key Laboratory for Quality Control of In Vitro Diagnostics, NMPA, ⁷Beijing Engineering Research Center of Immunological Reagents Clinical Research, ⁸School of Chinese Medicine, The University of Hong Kong, ⁹Department of Rheumatology and Clinical Immunology, Beijing Tiantan Hospital, Capital Medical University

Here, we present a protocol for the examination of oral Candida infection in patients with primary Sjögren's syndrome, which can be used for timely treatment and, thereafter, avoiding related complications.