Multimodal Cross-Device and Marker-Free Co-Registration of Preclinical Imaging ModalitiesMirko Thamm 1,2, Justin J. Jeffery 3, Yapei Zhang 4, Bryan R. Smith 4, Stephen Marchant 5, Fabian Kiessling 1,6, Felix Gremse 1,2
1Institute for Experimental Molecular Imaging, RWTH Aachen University, 2Gremse-IT GmbH, 3Carbone Cancer Center, University of Wisconsin, 4Department of Biomedical Engineering and Institute for Quantitative Health Science and Engineering, Michigan State University, 5MediLumine Inc., 6Fraunhofer Institute for Digital Medicine MEVIS
The combination of multiple imaging modalities is often necessary to gain a comprehensive understanding of pathophysiology. This approach utilizes phantoms to generate a differential transformation between the coordinate systems of two modalities, which is then applied for co-registration. This method eliminates the need for fiducials in production scans.
