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The Barcelona Institute of Science and Technology (BIST)

1 ARTICLES PUBLISHED IN JoVE

Biology

High-Throughput Behavioral Aging and Lifespan Assays Using the Lifespan Machine

Andrea Del Carmen-Fabregat^1,2, Lucia Sedlackova¹, Natasha Oswal^1,2, Nicholas Stroustrup^1,2

¹Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), ²Universitat Pompeu Fabra (UPF)

The imaging platform "The Lifespan Machine" automates the lifelong observation of large populations. We show the steps required to perform lifespan, stress resistance, pathogenesis, and behavioral aging assays. The quality and scope of the data allow researchers to study interventions in aging despite the presence of biological and environmental variation.