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Okinawa Institute of Science and Technology

2 ARTICLES PUBLISHED IN JoVE

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Neuroscience

C. elegans Tracking and Behavioral Measurement
Jirapat Likitlersuang 1, Greg Stephens 2,3, Konstantine Palanski 1, William S. Ryu 1,4
1Donnelly Centre, University of Toronto, 2Department of Physics and Astronomy, Vrije Universiteit, 3Okinawa Institute of Science and Technology, 4Department of Physics, University of Toronto

We have developed a video-rate tracking microscope system that can record and quantify C. elegans behavior at high resolution and high speeds. We have also developed computational methods to reduce the dimensionality of the worm images to a fundamental set of measurements that completely describe the shape of the worm.

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Behavior

New Variations for Strategy Set-shifting in the Rat
Sho Aoki 1, Andrew W. Liu 1, Aya Zucca 1, Stefano Zucca 1, Jeffery R. Wickens 1
1Neurobiology Research Unit, Okinawa Institute of Science and Technology

Set-shifting, a form of behavioral flexibility, requires an attentional shift from one stimulus dimension to another. We extended an established rodent set-shifting task1 by requiring attention to different stimuli according to context. The task was combined with specific lesions to identify neuron subtypes underlying a successful shift.

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