R Adams Cowley Shock Trauma Center
2 ARTICLES PUBLISHED IN JoVE
Medicine
A Novel Microsurgical Model for Heterotopic, En Bloc Chest Wall, Thymus, and Heart Transplantation in Mice
Byoungchol Oh *1, Georg J. Furtmüller *1, Michael Sosin *1, Madeline L. Fryer 1, Lawrence J. Gottlieb 2,3, Michael R. Christy 4, Gerald Brandacher 1,5,6, Amir H. Dorafshar 1,5,6
1Johns Hopkins University School of Medicine, 2Burn and Complex Wound Center, 3Section of Plastic and Reconstructive Surgery, University of Chicago Medical Center, 4Division of Plastic, Reconstructive, and Maxillofacial Surgery, R Adams Cowley Shock Trauma Center, 5Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, 6Vascularized Composite Allotransplantation (VCA) Lab, Johns Hopkins University School of Medicine
To study combined solid organ and vascularized composite allotransplantation, we describe a novel heterotopic en bloc chest wall, thymus, and heart transplant model in mice using a cervical non-suture cuff technique.
Medicine
Development of a Selective Aortic Arch Perfusion System in a Porcine Model of Exsanguination Cardiac Arrest
Marta J. Madurska 1, Hossam Abdou 1, Michael J. Richmond 1, Noha N. Elansary 1, Peng F. Wong 2, Todd E. Rasmussen 3, Thomas M. Scalea 1, Jonathan J. Morrison 1
1R Adams Cowley Shock Trauma Center, 2Department of Vascular Surgery, The James Cook University Hospital, 3Uniformed Services University of the Health Sciences
The goal of this protocol is to demonstrate a porcine exsanguination cardiac arrest model and a specifically built selective aortic arch perfusion circuit for translational research.
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